TMC1 Gene Deafness, autosomal recessive type 7 NGS Genetic Test
Short Name: TMC1 Deafness Test
TMC1 Gene Deafness, autosomal recessive type 7 NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in Results are available within 3 to 4 weeks after sample receipt.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
The purpose of this test is to diagnose mutations in the TMC1 gene that cause autosomal recessive deafness type 7. It helps in confirming the genetic basis of hearing loss, guiding treatment decisions, and providing information for family planning and genetic counseling.
- Test Code
- 4747
- Price
- ₹20,000
- Sample Type
- Blood or Extracted DNA or One drop Blood on FTA Card
- Result Time
- Results are available within 3 to 4 weeks after sample receipt.
- Fasting Required
- No
- Method
- Next-Generation Sequencing (NGS)
Sample Collection
No specific preparation required. Provide clinical history and family pedigree if available.
Method: Venipuncture for blood sample or FTA card collection
Laboratory Analysis
A blood sample will be collected by a trained phlebotomist. For FTA card, a drop of blood is applied.
Report Delivery
Apply pressure to the puncture site. Resume normal activities.
Timeline: Results are available within 3 to 4 weeks after sample receipt.
Patient Instructions
About This Test
Who Should Get This Test
The purpose of this test is to diagnose mutations in the TMC1 gene that cause autosomal recessive deafness type 7. It helps in confirming the genetic basis of hearing loss, guiding treatment decisions, and providing information for family planning and genetic counseling.
How to Prepare
- Ensure proper identification
- Use sterile equipment
- Label samples correctly
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"Genetic testing for TMC1 mutations is essential for families with a history of hearing loss, enabling early intervention and informed family planning."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Insufficient sample volume
- Contaminated sample
- Incorrect labeling
Understanding Your Results
Pathogenic variant detected
Confirms diagnosis of TMC1-related deafness. Genetic counseling recommended.
No pathogenic variant detected
TMC1 gene mutation not found. Consider other genetic tests or clinical evaluation.
If you have a family history of hearing loss or experience symptoms of deafness, consult a geneticist or ENT specialist for evaluation and testing.
Limitations
- ⚠May not detect all types of mutations in the TMC1 gene
- ⚠Results require interpretation by a geneticist
- ⚠Does not rule out other genetic causes of deafness
Risks & Considerations
- ●Minimal risk from blood draw, such as bruising or infection
- ●Psychological impact of genetic results
Interfering Factors
- ●Sample contamination
- ●Degraded DNA
- ●Technical errors in sequencing
Compare With Similar Tests
| Test | TMC1 Gene Deafness, autosomal recessive type 7 NGS Genetic Test | GJB2 Gene Test | SLC26A4 Gene Test | Whole Exome Sequencing |
|---|---|---|---|---|
| Comparison | TMC1 Gene Deafness, autosomal recessive type 7 NGS Genetic Test | Tests for connexin 26 mutations, common cause of genetic deafness. | For Pendred syndrome and related deafness. | Broader analysis of all genes, more comprehensive but costly. |
Frequently Asked Questions
What is TMC1 gene deafness?
How is the TMC1 gene deafness test performed?
What is the cost of the TMC1 gene deafness NGS genetic test?
Is home sample collection available for this test?
How long does it take to get the test results?
What do the test results indicate?
Can this test be used for family planning purposes?
Are there any risks associated with the test?
How accurate is NGS technology for this test?
What should I do if the test result is positive?
Can children undergo this genetic test?
Is genetic counseling provided with the test?
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₹20,000Reference Laboratory Services
We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
Your Data Privacy
Your medical data is protected under Indian law.
✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.
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