TNNI2 Gene Arthrogryposis, distal, type 2B NGS Genetic Test
Short Name: TNNI2 Arthrogryposis Test
Also known as: Distal Arthrogryposis Type 2B, TNNI2-related arthrogryposis, DA2B
TNNI2 Gene Arthrogryposis, distal, type 2B NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 Weeks. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
The purpose of this test is to identify mutations in the TNNI2 gene that cause distal arthrogryposis type 2B, aiding in accurate diagnosis, prognosis, and personalized medical management.
- Test Code
- 4847
- Price
- ₹20,000
- Sample Type
- Blood or Extracted DNA or One drop Blood on FTA Card
- Result Time
- 3 to 4 Weeks
- Fasting Required
- No
- Method
- Next-Generation Sequencing (NGS)
Sample Collection
No special preparation is required. Provide clinical history and undergo genetic counseling if recommended.
Method: Venipuncture or FTA card spotting
Laboratory Analysis
A blood sample will be drawn from a vein in the arm or a drop of blood will be applied to an FTA card.
Report Delivery
Apply pressure to the puncture site to prevent bleeding. Resume normal activities.
Timeline: 3 to 4 Weeks
Patient Instructions
About This Test
Who Should Get This Test
The purpose of this test is to identify mutations in the TNNI2 gene that cause distal arthrogryposis type 2B, aiding in accurate diagnosis, prognosis, and personalized medical management.
How to Prepare
- Ensure proper identification of the patient
- Use sterile equipment for blood collection
- Label samples correctly with patient details
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"This NGS genetic test is essential for confirming TNNI2 gene mutations in suspected cases of distal arthrogryposis type 2B, enabling early diagnosis, genetic counseling, and tailored management plans."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed or contaminated samples
- Insufficient sample volume
- Incorrect labeling or documentation
Understanding Your Results
Positive for pathogenic variant
Confirms diagnosis of TNNI2-related distal arthrogryposis type 2B. Genetic counseling and management recommended.
Negative for pathogenic variant
No mutations detected in TNNI2 gene. Consider other genetic causes or clinical evaluation.
Variant of uncertain significance
Further testing or family studies may be needed for clarification.
Consult a geneticist or specialist if symptoms of arthrogryposis are present, for family planning if there is a family history, or after receiving test results for guidance.
Limitations
- ⚠May not detect all genetic variants or mutations
- ⚠Requires genetic counseling for interpretation
- ⚠Results should be correlated with clinical findings
Risks & Considerations
- ●Minimal risk from blood draw, such as bruising or infection
- ●No significant risks associated with genetic testing itself
Interfering Factors
- ●Sample contamination
- ●Degraded DNA quality
- ●Incorrect sample collection or storage
Frequently Asked Questions
What is the TNNI2 Gene Arthrogryposis, distal, type 2B NGS Genetic Test?
Who should consider this test?
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What are the symptoms of TNNI2-related arthrogryposis?
Is fasting required for this test?
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What is the cost of the test?
Is home sample collection available?
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Is genetic counseling recommended?
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Reference Laboratory Services
We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
Your Data Privacy
Your medical data is protected under Indian law.
✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.
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