TP63 Gene Ectodactyly, ectodermal dysplasia, and cleft lip/palate syndrome type 3 NGS Genetic Test
Short Name: TP63 Gene NGS Test
Also known as: EEC Syndrome Type 3, TP63-Related Disorders
TP63 Gene Ectodactyly, ectodermal dysplasia, and cleft lip/palate syndrome type 3 NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses NGS (Next Generation Sequencing) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 Weeks. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
The purpose of the TP63 Gene NGS Genetic Test is to detect mutations in the TP63 gene that cause EEC syndrome type 3, enabling definitive diagnosis, guiding clinical management, facilitating genetic counseling for families, and supporting research into genetic disorders.
- Test Code
- 2729
- Price
- ₹20,000
- Sample Type
- Blood or Extracted DNA or One drop Blood on FTA Card
- Result Time
- 3 to 4 Weeks
- Fasting Required
- No
- Method
- NGS (Next Generation Sequencing)
Sample Collection
Provide clinical history of the patient and undergo a genetic counseling session to draw a pedigree chart of affected family members. No fasting is required.
Method: Venipuncture
Laboratory Analysis
A blood sample is collected via venipuncture from a vein in the arm, or a drop of blood is placed on an FTA card. The procedure is quick and minimally invasive.
Report Delivery
The sample is labeled, stored at ambient room temperature, and transported to the laboratory for DNA extraction and NGS analysis.
Timeline: 3 to 4 Weeks
Patient Instructions
About This Test
Who Should Get This Test
The purpose of the TP63 Gene NGS Genetic Test is to detect mutations in the TP63 gene that cause EEC syndrome type 3, enabling definitive diagnosis, guiding clinical management, facilitating genetic counseling for families, and supporting research into genetic disorders.
How to Prepare
- Ensure the patient is relaxed and hydrated
- Use sterile equipment for blood collection
- Label the sample correctly with patient details
- For FTA cards, allow blood to dry completely before packaging
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"Early genetic testing for TP63 mutations is crucial for diagnosing EEC syndrome type 3, enabling timely intervention, management of symptoms, and informed family planning decisions."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed or clotted blood samples
- Insufficient sample volume
- Incorrect labeling or missing patient information
Understanding Your Results
Positive for pathogenic variant
Confirms diagnosis of EEC syndrome type 3. Genetic counseling and multidisciplinary management are recommended.
Negative for pathogenic variant
No mutations detected in the TP63 gene. Clinical correlation and additional testing may be needed if symptoms persist.
Variant of uncertain significance (VUS)
A genetic variant was found, but its clinical significance is unknown. Follow-up testing and family studies may be advised.
Consult a doctor if you or your child exhibit symptoms such as missing fingers/toes, cleft lip/palate, abnormal nails/teeth, or skin/hair issues, especially with a family history of genetic disorders.
Limitations
- ⚠May not detect all types of genetic variants, such as large deletions or duplications
- ⚠Results require interpretation by a genetic specialist
- ⚠Does not rule out other genetic conditions with similar symptoms
Risks & Considerations
- ●Minor bruising or discomfort at the blood draw site
- ●Very low risk of infection
- ●Emotional impact of genetic results, requiring counseling support
Interfering Factors
- ●Poor sample quality or insufficient DNA
- ●Contamination during sample collection or processing
- ●Recent blood transfusions may affect DNA analysis
Frequently Asked Questions
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We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
Your Data Privacy
Your medical data is protected under Indian law.
✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.
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