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DNA Labs India

TPRN Gene Deafness, autosomal recessive type 79 NGS Genetic Test

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TPRN Gene Deafness, autosomal recessive type 79 NGS Genetic Test

Short Name: TPRN Gene Deafness Test

Also known as: DFNB79 Deafness, Autosomal Recessive Deafness Type 79

TPRN Gene Deafness, autosomal recessive type 79 NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses NGS Technology on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 weeks. Free home collection in 300+ cities across India.

NGS Genetic Test🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr SULOCHANA HEMCHANDRA HOLLA

Dr SULOCHANA HEMCHANDRA HOLLA

Consultant Medical Geneticist · Reg: 8532

Last reviewed: September 7, 2026

Overview

This test helps diagnose TPRN gene-related deafness, providing genetic information for treatment, management, and family counseling.

Test Code
4750
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
3 to 4 weeks
Fasting Required
No
Method
NGS Technology
Step 1

Sample Collection

No special preparation required. Genetic counseling is recommended.

Method: Venipuncture or finger prick

Step 2

Laboratory Analysis

A blood sample will be drawn by a trained phlebotomist using sterile techniques.

Step 3

Report Delivery

Apply pressure to the puncture site to stop bleeding. Keep the area clean.

Timeline: 3 to 4 weeks

Patient Instructions

1
Before the Test:Genetic counseling session to discuss family history and test implications.
2
During the Test:Sample collection and processing in the laboratory using NGS technology.
3
After the Test:Report generation, delivery, and follow-up counseling as needed.

About This Test

Who Should Get This Test

This test helps diagnose TPRN gene-related deafness, providing genetic information for treatment, management, and family counseling.

How to Prepare

  • Ensure proper patient identification
  • Use sterile collection equipment
  • Label samples correctly

Doctor's Notes

Reviewed by — MBBS, MD (Medical Genetics) · Reg. No. 8532

"Genetic testing for TPRN gene mutations is crucial for early diagnosis and management of hereditary deafness, aiding in family planning and treatment decisions."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card
Sample Volume5-10 ml blood
ContainerEDTA tube or FTA card
Collection MethodVenipuncture or finger prick

Sample Stability

Blood: Store at 2-8°C for up to 24 hours
FTA card: Stable at room temperature
Sample Rejection Criteria:
  • Hemolyzed or clotted sample
  • Insufficient sample volume
  • Improper labeling

Understanding Your Results

Results indicate the presence or absence of pathogenic variants in the TPRN gene associated with autosomal recessive deafness type 79.
📊

Positive

Pathogenic variant detected, confirming diagnosis of autosomal recessive deafness type 79. Genetic counseling recommended.

📊

Negative

No pathogenic variants detected. Clinical correlation advised if symptoms persist.

📊

Variant of Uncertain Significance

Further testing or family studies may be required for clarification.

⚠️ When to Consult a Doctor:

Consult a geneticist or ENT specialist if you have a family history of deafness, experience hearing loss, or receive positive test results.

Limitations

  • ⚠May not detect all genetic variants
  • ⚠Requires genetic counseling for interpretation
  • ⚠Not a standalone diagnostic tool

Risks & Considerations

  • ●Minimal risk from blood draw (e.g., bruising, infection)
  • ●Genetic privacy and psychological impact

Interfering Factors

  • ●Sample contamination
  • ●Degraded DNA
  • ●Incorrect sample handling

Compare With Similar Tests

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ComparisonTPRN Gene Deafness, autosomal recessive type 79 NGS Genetic Test

Frequently Asked Questions

What is TPRN Gene Deafness?
TPRN Gene Deafness is a genetic condition caused by mutations in the TPRN gene, leading to autosomal recessive deafness type 79 (DFNB79).
What is autosomal recessive type 79 deafness?
It is a form of hereditary hearing loss where two copies of a mutated TPRN gene are inherited, causing deafness from birth or early childhood.
How is the NGS Genetic Test performed?
The test uses Next-Generation Sequencing to analyze the TPRN gene from a blood or DNA sample, identifying pathogenic variants.
What are the symptoms of TPRN Gene Deafness?
Common symptoms include hearing loss from birth, difficulty understanding speech in noise, and tinnitus.
Who should consider this test?
Individuals with congenital hearing loss, family history of hereditary deafness, or unexplained hearing impairment.
What is the cost of the test?
The test costs INR 20,000, with free home sample collection available across India.
How long does it take to get results?
Results are typically available within 3 to 4 weeks after sample collection.
Is home sample collection available?
Yes, DNA Labs India offers free home sample collection for online bookings in numerous cities across India.
What do the test results mean?
Results indicate whether pathogenic TPRN gene variants are detected, aiding in diagnosis and management. Genetic counseling is recommended for interpretation.
Is genetic counseling necessary?
Yes, genetic counseling is recommended before and after testing to understand implications, family risks, and next steps.
Are there any risks associated with the test?
Risks are minimal, primarily related to blood draw (e.g., bruising). Genetic testing may have psychological or privacy implications.
How accurate is the NGS Genetic Test?
NGS technology is highly accurate for detecting genetic variants, but accuracy depends on sample quality and laboratory protocols.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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