TRIOBP Gene Deafness, autosomal recessive type 28 NGS Genetic Test
Short Name: TRIOBP DFNB28 NGS Test
Also known as: DFNB28 Deafness, TRIOBP-Related Hearing Loss
TRIOBP Gene Deafness, autosomal recessive type 28 NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses NGS Technology on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 weeks. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Pasupathy Arumugam
Consultant Pathologist · Reg: 21521
Last reviewed: September 7, 2026
Overview
To detect mutations in the TRIOBP gene that cause autosomal recessive deafness type 28, aiding in accurate diagnosis, genetic counseling, family planning, and management of hereditary hearing loss.
- Test Code
- 2330
- Price
- ₹20,000
- Sample Type
- Blood or Extracted DNA or One drop Blood on FTA Card
- Result Time
- 3 to 4 weeks
- Fasting Required
- No
- Method
- NGS Technology
Sample Collection
Genetic counseling session to discuss family history and obtain informed consent.
Method: Venipuncture
Laboratory Analysis
Blood sample collected via venipuncture by trained phlebotomist.
Report Delivery
Sample processed for NGS analysis; results reviewed by geneticist.
Timeline: 3 to 4 weeks
Patient Instructions
About This Test
Who Should Get This Test
To detect mutations in the TRIOBP gene that cause autosomal recessive deafness type 28, aiding in accurate diagnosis, genetic counseling, family planning, and management of hereditary hearing loss.
How to Prepare
- No fasting required
- Provide detailed clinical and family history
- Bring valid identification
- Ensure proper labeling of sample
Doctor's Notes
Reviewed by Dr Pasupathy Arumugam — MBBS, MD (Pathology) · Reg. No. 21521
"Genetic testing for TRIOBP mutations is essential for accurate diagnosis, family counseling, and management of hereditary deafness, enabling targeted interventions and informed decision-making."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed or clotted sample
- Insufficient sample volume
- Improperly labeled or contaminated sample
Understanding Your Results
Positive
Pathogenic variant detected in TRIOBP gene, confirming diagnosis of DFNB28. Genetic counseling recommended for family implications.
Negative
No pathogenic variants detected in TRIOBP gene. Consider other genetic causes or environmental factors for hearing loss.
Variant of Uncertain Significance
A variant identified but clinical significance unknown. Further testing and consultation advised.
If you experience symptoms of hearing loss, have a family history of deafness, or receive a positive genetic test result, consult a geneticist or ENT specialist for management.
Limitations
- ⚠Only detects mutations in TRIOBP gene
- ⚠May not identify all genetic causes of deafness
- ⚠Results require genetic counseling for interpretation
Risks & Considerations
- ●Minimal risk from blood draw (bruising, infection)
- ●Psychological impact of genetic results
- ●Potential for incidental findings
Interfering Factors
- ●Poor sample quality
- ●DNA contamination
- ●Hemolyzed blood sample
Compare With Similar Tests
| Test | TRIOBP Gene Deafness, autosomal recessive type 28 NGS Genetic Test | GJB2 Gene Deafness NGS Test | SLC26A4 Gene Deafness NGS Test | Comprehensive Hearing Loss Gene Panel | Usher Syndrome Genetic Test |
|---|---|---|---|---|---|
| Comparison | TRIOBP Gene Deafness, autosomal recessive type 28 NGS Genetic Test | Targets GJB2 gene mutations, another common cause of hereditary deafness. | Detects mutations in SLC26A4 gene, associated with Pendred syndrome and deafness. | Tests multiple genes for hearing loss, providing broader coverage. | Diagnoses Usher syndrome, which includes hearing loss and vision impairment. |
Frequently Asked Questions
What is TRIOBP gene deafness?
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What is the cost of the TRIOBP gene deafness test in India?
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Is home sample collection available?
What are the symptoms of TRIOBP gene deafness?
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₹20,000Reference Laboratory Services
We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
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