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TRPM6 Gene Hypomagnesemia type 1 NGS Genetic Test

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TRPM6 Gene Hypomagnesemia type 1 NGS Genetic Test

Short Name: TRPM6 Hypomagnesemia Type 1 Test

TRPM6 Gene Hypomagnesemia type 1 NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses NGS Technology on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 Weeks. Free home collection in 300+ cities across India.

NGS Genetic Test🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr SULOCHANA HEMCHANDRA HOLLA

Dr SULOCHANA HEMCHANDRA HOLLA

Consultant Medical Geneticist · Reg: 8532

Last reviewed: September 7, 2026

Overview

To diagnose TRPM6 gene hypomagnesemia type 1 by detecting pathogenic mutations in the TRPM6 gene using NGS technology, aiding in clinical management and genetic counseling.

Test Code
2108
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
3 to 4 Weeks
Fasting Required
No
Method
NGS Technology
Step 1

Sample Collection

No specific preparation required. Provide clinical history and undergo genetic counseling if recommended.

Method: Venipuncture or Finger-prick

Step 2

Laboratory Analysis

Sample collected via venipuncture or finger-prick in a sterile environment by a trained phlebotomist.

Step 3

Report Delivery

Apply pressure to the collection site to prevent bruising. Store sample as per lab instructions.

Timeline: 3 to 4 Weeks

Patient Instructions

1
Before the Test:Ensure genetic counseling is scheduled. Provide complete medical history to the physician.
2
During the Test:A blood sample is drawn. The process is quick with minimal discomfort.
3
After the Test:Monitor the collection site for any signs of infection. Results will be available in 3-4 weeks.

About This Test

Who Should Get This Test

To diagnose TRPM6 gene hypomagnesemia type 1 by detecting pathogenic mutations in the TRPM6 gene using NGS technology, aiding in clinical management and genetic counseling.

How to Prepare

  • Use aseptic technique
  • Label sample correctly
  • Transport at ambient room temperature

Doctor's Notes

Reviewed by — MBBS, MD (Medical Genetics) · Reg. No. 8532

"Early genetic testing for TRPM6 mutations is crucial for managing hypomagnesemia, preventing complications, and guiding family planning decisions."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card
ContainerEDTA tube or FTA card
Collection MethodVenipuncture or Finger-prick

Sample Stability

Ambient temperature24 hours
Refrigerated7 days
Sample Rejection Criteria:
  • Hemolyzed or clotted sample
  • Insufficient volume
  • Improper labeling

Understanding Your Results

Test results indicate the presence or absence of pathogenic mutations in the TRPM6 gene. A positive result confirms Hypomagnesemia Type 1, while a negative result suggests no detected mutations, but clinical correlation is advised.
📊

Pathogenic variant detected

Confirms diagnosis of TRPM6 Gene Hypomagnesemia Type 1. Consult a geneticist for management.

📊

No pathogenic variant detected

Mutations not found. Symptoms may be due to other causes; further evaluation recommended.

⚠️ When to Consult a Doctor:

Consult a doctor if you experience symptoms like persistent muscle weakness, seizures, or abnormal heart rhythms, especially with a family history of hypomagnesemia.

Limitations

  • ⚠May not detect all genetic variants or polymorphisms
  • ⚠Results require interpretation by a genetic counselor
  • ⚠Not suitable for prenatal diagnosis

Risks & Considerations

  • ●Minor bruising or pain at needle site
  • ●Rare risk of infection
  • ●Emotional impact of genetic results

Interfering Factors

  • ●Contaminated DNA sample
  • ●Improper sample storage
  • ●Recent blood transfusion

Compare With Similar Tests

TestTRPM6 Gene Hypomagnesemia type 1 NGS Genetic Test
ComparisonTRPM6 Gene Hypomagnesemia type 1 NGS Genetic Test

Frequently Asked Questions

What is TRPM6 Gene Hypomagnesemia Type 1?
It is a rare genetic disorder caused by mutations in the TRPM6 gene, leading to impaired magnesium absorption, which can cause symptoms like muscle weakness and seizures.
What are the symptoms of this disorder?
Common symptoms include muscle weakness, cramps, seizures, tetany, abnormal heart rhythm, low calcium levels, and osteoporosis.
How is the test performed?
The test uses NGS technology to analyze the TRPM6 gene from a blood or DNA sample, detecting mutations associated with the disorder.
What is the cost of the test?
The test costs INR 20000 in India, with free home sample collection available.
Is home sample collection available?
Yes, free home sample collection is offered for online bookings across many cities in India.
How long does it take to get results?
Results are typically available in 3 to 4 weeks, delivered via online portal, email, or WhatsApp.
What do the test results mean?
A positive result confirms mutations in the TRPM6 gene, indicating Hypomagnesemia Type 1. A negative result means no mutations were detected, but clinical correlation is advised.
Is the test covered by insurance?
Genetic tests are often not covered by insurance in India. Check with your provider for specific policies.
Are there any risks to the test?
Risks are minimal, including minor bruising from blood draw and potential emotional impact of genetic results.
What should I do before the test?
Provide your clinical history and undergo genetic counseling if recommended. No fasting is required.
Can the test be done on children?
Yes, the test is suitable for all age groups, including children, when clinically indicated.
What are the treatment options after diagnosis?
Treatment includes magnesium and calcium supplements, vitamin D, bisphosphonate therapy for osteoporosis, and lifestyle changes as guided by a physician.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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