Skip to main content
DNA Labs India

TUBA1A Gene Lissencephaly type 3 NGS Genetic Test

DNA Labs India | ISO 9001:2015 Certified

TUBA1A Gene Lissencephaly type 3 NGS Genetic Test

TUBA1A Gene Lissencephaly type 3 NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 Weeks. Free home collection in 300+ cities across India.

PediatricsPediatric🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr Pasupathy Arumugam

Dr Pasupathy Arumugam

Consultant Pathologist · Reg: 21521

Last reviewed: September 7, 2026

Overview

To diagnose TUBA1A gene mutations associated with lissencephaly type 3, enabling accurate identification of the genetic cause of the disorder for proper management and genetic counseling.

Test Code
2753
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
3 to 4 Weeks
Fasting Required
No
Method
Next-Generation Sequencing (NGS)
Step 1

Sample Collection

Clinical history of the patient and a genetic counseling session to draw a pedigree chart of family members affected with TUBA1A gene lissencephaly type 3.

Step 2

Laboratory Analysis

Standard blood draw or sample collection procedure as per laboratory guidelines.

Step 3

Report Delivery

Sample is processed and analyzed using NGS technology; results are reviewed and reported.

Timeline: 3 to 4 Weeks

Patient Instructions

1
Before the Test:Clinical history of the patient and a genetic counseling session to draw a pedigree chart of family members affected with TUBA1A gene lissencephaly type 3.
2
During the Test:Blood sample or extracted DNA is collected and sent for NGS analysis.
3
After the Test:Results are reviewed, and a clinical report is generated with raw data files provided.

About This Test

Who Should Get This Test

To diagnose TUBA1A gene mutations associated with lissencephaly type 3, enabling accurate identification of the genetic cause of the disorder for proper management and genetic counseling.

How to Prepare

  • Provide detailed clinical history of the patient.
  • Undergo genetic counseling to assess family history and draw a pedigree chart.
  • Ensure sample is collected in appropriate container and stored at ambient room temperature.

Doctor's Notes

Reviewed by — MBBS, MD (Pathology) · Reg. No. 21521

"Early genetic testing for TUBA1A mutations is crucial for accurate diagnosis and management of lissencephaly type 3, aiding in personalized care and genetic counseling."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card

Understanding Your Results

Results from the TUBA1A Gene Lissencephaly Type 3 NGS Genetic Test indicate the presence or absence of mutations in the TUBA1A gene. Interpretation should be done by a qualified geneticist or healthcare provider.
📊

No pathogenic variants detected

Normal result; no mutations in TUBA1A gene identified. Clinical correlation recommended if symptoms persist.

📊

Pathogenic variant(s) identified

Abnormal result; confirms genetic diagnosis of lissencephaly type 3. Genetic counseling and management planning advised.

⚠️ When to Consult a Doctor:

Consult a doctor if an individual exhibits symptoms such as developmental delay, seizures, or microcephaly, or if there is a family history of lissencephaly or related neurological disorders.

Limitations

  • ⚠This test only analyzes the TUBA1A gene and may not detect mutations in other genes associated with lissencephaly or similar disorders.

Risks & Considerations

  • ●Minor bruising or discomfort at the blood draw site
  • ●Rare risk of infection

Frequently Asked Questions

What is TUBA1A Gene Lissencephaly Type 3?
It is a rare genetic disorder caused by mutations in the TUBA1A gene, leading to abnormal brain development characterized by a smooth brain surface (lissencephaly).
What are the common symptoms of this disorder?
Symptoms include severe developmental delay, intellectual disability, seizures, poor muscle tone, difficulty swallowing, abnormal muscle stiffness, scoliosis, and small head size.
How is the TUBA1A Gene Lissencephaly Type 3 NGS Genetic Test performed?
The test uses Next-Generation Sequencing (NGS) to analyze a DNA sample from blood or extracted DNA to detect mutations in the TUBA1A gene.
What is the cost of the test in India?
The cost is INR 20,000 at DNA Labs India, which may include home sample collection.
Is the test covered by insurance?
Genetic testing for this condition is not typically covered by insurance, but financial assistance programs may be available.
How long does it take to get the test results?
Results are usually available within 3 to 4 weeks after sample collection.
What sample is required for the test?
The test can be performed using blood, extracted DNA, or one drop of blood on an FTA card.
Is home sample collection available?
Yes, DNA Labs India offers free home sample collection for online bookings across many cities in India.
What does a positive test result mean?
A positive result indicates the presence of pathogenic mutations in the TUBA1A gene, confirming a diagnosis of lissencephaly type 3.
Can this test be used for prenatal diagnosis?
This test is primarily for postnatal diagnosis; prenatal testing may require different methods and genetic counseling.
What is the accuracy of NGS testing for this condition?
NGS is a highly accurate and sensitive method for detecting genetic mutations, even in cases where other tests are inconclusive.
How should I prepare for the test?
No special preparation is needed, but providing clinical history and undergoing genetic counseling is recommended before testing.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

Related Tests

Amino Acids Qualitative Two Dimensional Urine Test

₹1,439

Succinylacetone Urine Test

₹5,000

RXFP2 Gene Cryptorchidism NGS Genetic Test

₹20,000

EFNB1 Gene Craniofrontonasal syndrome NGS Genetic Test

₹20,000

MNX1 Gene Currarino syndrome NGS Genetic Test

₹20,000

FGFR1 Gene Craniosynostosis, FGFR1 related NGS Genetic Test

₹20,000
For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

Book Your Test

Enter your details and we'll connect you within 15 minutes.

🧬

Quick Connect

Enter your mobile number and we’ll connect you with the team.

+91

✅ Connecting you now...

🔒 Your number is used to respond to this request.