UCP2 Gene Hyperinsulinism, UCP2 related NGS Genetic Test
Short Name: UCP2 NGS Test
Also known as: UCP2 Gene Mutation Test, Hyperinsulinism Genetic Test, NGS for UCP2
UCP2 Gene Hyperinsulinism, UCP2 related NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in Reports are typically available within 3 to 4 weeks after sample receipt at the laboratory.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
The purpose of this test is to detect mutations in the UCP2 gene that cause hyperinsulinism. It aids in confirming diagnosis, understanding genetic inheritance, guiding treatment decisions, and providing genetic counseling for families.
- Test Code
- 2090
- Price
- ₹20,000
- Sample Type
- Blood or Extracted DNA or One drop Blood on FTA Card
- Result Time
- Reports are typically available within 3 to 4 weeks after sample receipt at the laboratory.
- Fasting Required
- No
- Method
- Next-Generation Sequencing (NGS)
Sample Collection
No special preparation required. Provide detailed clinical history and family pedigree during genetic counseling session.
Method: Venipuncture or FTA card collection
Laboratory Analysis
A small blood sample will be collected via venipuncture or a blood drop on an FTA card by a trained professional.
Report Delivery
Apply pressure to the puncture site to prevent bleeding. Resume normal activities immediately.
Timeline: Reports are typically available within 3 to 4 weeks after sample receipt at the laboratory.
Patient Instructions
About This Test
Who Should Get This Test
The purpose of this test is to detect mutations in the UCP2 gene that cause hyperinsulinism. It aids in confirming diagnosis, understanding genetic inheritance, guiding treatment decisions, and providing genetic counseling for families.
How to Prepare
- Fasting is not required for this genetic test
- Ensure proper labeling of the sample with patient details
- Store blood samples at room temperature and transport as per lab guidelines
- Use FTA card for convenient home collection if applicable
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"Early genetic testing for UCP2 mutations can guide treatment and prevent complications in hyperinsulinism, especially in pediatric cases."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed or clotted blood samples
- Insufficient sample volume
- Improperly labeled or contaminated samples
Understanding Your Results
Pathogenic Mutation Detected
Confirms diagnosis of UCP2-related hyperinsulinism. Guides treatment and genetic counseling for families.
Likely Pathogenic Variant
Strong evidence for causality. Clinical correlation and family studies recommended.
Variant of Uncertain Significance (VUS)
Further testing or functional studies may be needed for clarification.
Likely Benign or Benign
Unlikely to cause hyperinsulinism. Consider other diagnostic avenues.
If you or your child experiences symptoms of hypoglycemia, seizures, or has a family history of hyperinsulinism, consult a healthcare provider immediately for evaluation and possible genetic testing.
Limitations
- ⚠May not detect all types of genetic variations
- ⚠Results require clinical correlation with patient history
- ⚠Does not rule out other genetic or metabolic causes of hyperinsulinism
Risks & Considerations
- ●Minimal risk from blood draw, such as bruising or infection at the puncture site
- ●No significant risks associated with FTA card collection
Interfering Factors
- ●Degraded DNA samples
- ●Contamination during sample processing
- ●Technical errors in NGS sequencing
Compare With Similar Tests
| Test | UCP2 Gene Hyperinsulinism, UCP2 related NGS Genetic Test | ABCC8 Gene Test | KCNJ11 Gene Test | Comprehensive Hyperinsulinism Panel | Fasting Glucose Test | Insulin Level Testing |
|---|---|---|---|---|---|---|
| Comparison | UCP2 Gene Hyperinsulinism, UCP2 related NGS Genetic Test |
Frequently Asked Questions
What is UCP2 gene hyperinsulinism?
What are the common symptoms of UCP2 gene hyperinsulinism?
How is UCP2 gene hyperinsulinism diagnosed?
What is NGS genetic testing?
What is the cost of the UCP2 gene hyperinsulinism NGS genetic test in India?
Is home sample collection available for this test?
How long does it take to get the test results?
Is fasting required for the UCP2 gene hyperinsulinism genetic test?
What should I do if the test result is positive?
Can this test be performed on infants?
Is genetic counseling provided with the test?
How accurate is the NGS genetic test for UCP2 hyperinsulinism?
Related Tests
Reference Laboratory Services
We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
Your Data Privacy
Your medical data is protected under Indian law.
✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.
Book Your Test
Enter your details and we'll connect you within 15 minutes.