UQCC2 Gene Mitochondrial complex III deficiency, nuclear type 7 NGS Genetic Test
Short Name: UQCC2 Gene Test
Also known as: UQCC2-related mitochondrial disorder, Mitochondrial Complex III Deficiency Type 7, Nuclear type 7 complex III deficiency
UQCC2 Gene Mitochondrial complex III deficiency, nuclear type 7 NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 Weeks. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Pasupathy Arumugam
Consultant Pathologist · Reg: 21521
Last reviewed: September 3, 2026
Overview
The purpose of the UQCC2 Gene Mitochondrial Complex III Deficiency NGS Genetic Test is to detect mutations in the UQCC2 gene that cause mitochondrial complex III deficiency, nuclear type 7. This test aids in confirming diagnosis, guiding treatment decisions, and informing family planning for affected individuals.
- Test Code
- 2779
- Price
- ₹20,000
- Sample Type
- Blood or Extracted DNA or One drop Blood on FTA Card
- Result Time
- 3 to 4 Weeks
- Fasting Required
- No
- Method
- Next-Generation Sequencing (NGS)
Sample Collection
Provide detailed clinical history of the patient and undergo a genetic counseling session to draw a pedigree chart of family members affected with mitochondrial disorders.
Method: Venipuncture or FTA Card
Laboratory Analysis
Blood sample collected via venipuncture or one drop on FTA card by a trained phlebotomist.
Report Delivery
Sample is transported to the laboratory under ambient conditions for DNA extraction and NGS analysis.
Timeline: 3 to 4 Weeks
Patient Instructions
About This Test
Who Should Get This Test
The purpose of the UQCC2 Gene Mitochondrial Complex III Deficiency NGS Genetic Test is to detect mutations in the UQCC2 gene that cause mitochondrial complex III deficiency, nuclear type 7. This test aids in confirming diagnosis, guiding treatment decisions, and informing family planning for affected individuals.
How to Prepare
- Provide clinical history of the patient
- Undergo genetic counseling session
- Draw pedigree chart of family members
- Ensure sample is collected in appropriate container
Doctor's Notes
Reviewed by Dr Pasupathy Arumugam — MBBS, MD (Pathology) · Reg. No. 21521
"Genetic testing for UQCC2 mutations is crucial for accurate diagnosis and management of mitochondrial disorders. Consult a genetic counselor for personalized advice on family planning and treatment."
Last medically reviewed: September 3, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed or clotted sample
- Insufficient sample volume
- Improperly labeled sample
Understanding Your Results
Pathogenic variant detected
Confirms diagnosis of UQCC2-related mitochondrial complex III deficiency. Genetic counseling recommended.
No pathogenic variant detected
Reduces likelihood of UQCC2 gene mutation, but does not rule out other genetic causes. Further testing may be needed.
Variant of uncertain significance
Requires additional family studies or functional analysis. Consult genetic counselor for guidance.
Consult a doctor if symptoms such as developmental delay, muscle weakness, seizures, or lactic acidosis are present, especially with a family history of mitochondrial disorders.
Limitations
- ⚠May not detect all types of mutations (e.g., large deletions)
- ⚠Requires genetic counseling for interpretation
- ⚠Results may have variants of uncertain significance
Risks & Considerations
- ●Minimal risk from blood draw (e.g., bruising, infection)
- ●Genetic privacy concerns
- ●Psychological impact of results
Interfering Factors
- ●Sample contamination
- ●Degraded DNA
- ●Hemolyzed blood sample
Frequently Asked Questions
What is the UQCC2 Gene Mitochondrial Complex III Deficiency NGS Genetic Test?
What is the cost of the UQCC2 Gene Test in India?
What are the symptoms of UQCC2 Gene Mitochondrial Complex III Deficiency?
How is the UQCC2 Gene Test performed?
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What sample is required for the test?
Is fasting required before the test?
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What does a positive result mean?
Is the test accurate?
Does DNA Labs India provide raw data with the test?
Is home sample collection available?
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Reference Laboratory Services
We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
Your Data Privacy
Your medical data is protected under Indian law.
✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.
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