WNT4 Gene SERKAL syndrome NGS Genetic Test
Short Name: SERKAL Syndrome NGS Test
Also known as: WNT4-related syndrome
WNT4 Gene SERKAL syndrome NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 Weeks. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
The purpose of the WNT4 Gene SERKAL Syndrome NGS Genetic Test is to detect mutations in the WNT4 gene, enabling accurate diagnosis of SERKAL Syndrome. This helps in confirming the condition, guiding clinical management, and providing genetic counseling for affected individuals and their families.
- Test Code
- 2647
- Price
- ₹20,000
- Sample Type
- Blood or Extracted DNA or One drop Blood on FTA Card
- Result Time
- 3 to 4 Weeks
- Fasting Required
- No
- Method
- Next-Generation Sequencing (NGS)
Sample Collection
Clinical history review and genetic counseling session recommended to draw a pedigree chart of affected family members.
Method: Blood Draw or FTA Card
Laboratory Analysis
Standard blood draw via venipuncture or collection using an FTA card, following sterile techniques.
Report Delivery
Sample is labeled, stored at ambient room temperature, and transported to the laboratory for analysis.
Timeline: 3 to 4 Weeks
Patient Instructions
About This Test
Who Should Get This Test
The purpose of the WNT4 Gene SERKAL Syndrome NGS Genetic Test is to detect mutations in the WNT4 gene, enabling accurate diagnosis of SERKAL Syndrome. This helps in confirming the condition, guiding clinical management, and providing genetic counseling for affected individuals and their families.
How to Prepare
- Ensure proper patient identification and sample labeling
- Use sterile collection equipment
- Follow laboratory-specific protocols for blood or FTA card collection
- Avoid hemolysis during blood draw
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"Genetic testing is crucial for accurate diagnosis of SERKAL Syndrome to guide management and family planning."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed or clotted blood samples
- Insufficient sample volume
- Improper labeling or documentation
- Contaminated samples
Understanding Your Results
Pathogenic variant detected
Consistent with a diagnosis of SERKAL Syndrome. Clinical correlation and genetic counseling are recommended.
No pathogenic variant detected
SERKAL Syndrome is unlikely based on genetic analysis, but clinical evaluation should continue if symptoms persist.
Variant of uncertain significance (VUS)
Further testing or family studies may be needed for clarification. Consult a genetic specialist.
Consult a doctor if symptoms such as kidney abnormalities, genital anomalies, infertility, or delayed puberty are present, or for family planning advice if there is a family history of SERKAL Syndrome.
Limitations
- ⚠May not detect all types of mutations, such as large deletions or intronic variants
- ⚠Requires genetic counseling for interpretation
- ⚠Results may have psychological or familial implications
Risks & Considerations
- ●Minimal risk from blood draw, such as bruising or infection
- ●Potential psychological impact of genetic results
- ●Implications for family members regarding inheritance
Interfering Factors
- ●Sample degradation
- ●Contamination during collection or processing
- ●Technical errors in sequencing
Compare With Similar Tests
| Test | WNT4 Gene SERKAL syndrome NGS Genetic Test | Sanger Sequencing | Renal Function Panel | Hormonal Assay |
|---|---|---|---|---|
| Comparison | WNT4 Gene SERKAL syndrome NGS Genetic Test |
Frequently Asked Questions
What is SERKAL Syndrome?
What causes SERKAL Syndrome?
What are the common symptoms of SERKAL Syndrome?
How is SERKAL Syndrome diagnosed?
What is the NGS Genetic Test for SERKAL Syndrome?
What is the cost of the WNT4 Gene SERKAL Syndrome NGS Genetic Test?
Is home sample collection available for this test?
How long does it take to get the test results?
What do the test results indicate?
Is genetic counseling recommended before or after the test?
Can this test be used for prenatal diagnosis?
What are the risks associated with the genetic test?
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