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WNT7A Gene Fibular aplasia or hypoplasia, femoral bowing and poly-, syn-, and oligodactyly NGS Genetic Test

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WNT7A Gene Fibular aplasia or hypoplasia, femoral bowing and poly-, syn-, and oligodactyly NGS Genetic Test

Short Name: WNT7A Gene NGS Test

Also known as: WNT7A Gene Mutation Test, Limb Malformation Genetic Test

WNT7A Gene Fibular aplasia or hypoplasia, femoral bowing and poly-, syn-, and oligodactyly NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 Weeks. Free home collection in 300+ cities across India.

Genetic TestPediatric🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr SULOCHANA HEMCHANDRA HOLLA

Dr SULOCHANA HEMCHANDRA HOLLA

Consultant Medical Geneticist · Reg: 8532

Last reviewed: September 7, 2026

Overview

To identify mutations in the WNT7A gene for accurate diagnosis of fibular aplasia, femoral bowing, and poly/syn/oligodactyly, enabling personalized treatment and genetic counseling.

Test Code
5742
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
3 to 4 Weeks
Fasting Required
No
Method
Next-Generation Sequencing (NGS)
Step 1

Sample Collection

Provide clinical history and attend a genetic counseling session to draw a pedigree chart.

Method: Venipuncture or FTA Card

Step 2

Laboratory Analysis

Standard blood draw via venipuncture or collection using an FTA card.

Step 3

Report Delivery

Sample is processed and analyzed using NGS technology.

Timeline: 3 to 4 Weeks

Patient Instructions

1
Before the Test:Genetic counseling and clinical history assessment.
2
During the Test:Blood sample collection and DNA extraction.
3
After the Test:NGS analysis and result interpretation with counseling.

About This Test

Who Should Get This Test

To identify mutations in the WNT7A gene for accurate diagnosis of fibular aplasia, femoral bowing, and poly/syn/oligodactyly, enabling personalized treatment and genetic counseling.

How to Prepare

  • Provide detailed clinical history
  • Attend genetic counseling session
  • Ensure proper sample collection and labeling

Doctor's Notes

Reviewed by — MBBS, MD (Medical Genetics) · Reg. No. 8532

"This test is crucial for early diagnosis and management of rare genetic limb disorders, aiding in personalized treatment plans."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card
Sample Volume5 mL
ContainerEDTA tube or FTA card
Collection MethodVenipuncture or FTA Card

Sample Stability

Stable for 24 hours at room temperature
Long-term storage at -20°C
Sample Rejection Criteria:
  • Hemolyzed sample
  • Insufficient sample volume
  • Improperly labeled sample

Understanding Your Results

Results indicate the presence or absence of pathogenic variants in the WNT7A gene.
📊

Positive for pathogenic variant

Confirms diagnosis of WNT7A-related disorder; genetic counseling recommended.

📊

Negative for pathogenic variant

No mutations detected; clinical correlation advised.

📊

Variant of unknown significance

Further testing or family studies may be needed.

⚠️ When to Consult a Doctor:

If symptoms such as limb abnormalities are present or if there is a family history of genetic disorders.

Limitations

  • ⚠May not detect all genetic variants
  • ⚠Requires genetic counseling for accurate interpretation

Risks & Considerations

  • ●Minimal risks from blood draw (e.g., bruising)
  • ●Psychological impact of genetic results

Interfering Factors

  • ●Hemolyzed sample
  • ●Contaminated sample

Compare With Similar Tests

TestWNT7A Gene Fibular aplasia or hypoplasia, femoral bowing and poly-, syn-, and oligodactyly NGS Genetic TestFGFR3 Gene TestSHH Gene TestBMP Gene PanelSkeletal Dysplasia Panel
ComparisonWNT7A Gene Fibular aplasia or hypoplasia, femoral bowing and poly-, syn-, and oligodactyly NGS Genetic TestFocuses on different skeletal dysplasias.Related to holoprosencephaly and limb defects.Tests multiple genes involved in bone morphogenesis.Comprehensive panel for various bone disorders.

Frequently Asked Questions

What is the WNT7A Gene NGS Genetic Test?
It is a genetic test that uses Next-Generation Sequencing to detect mutations in the WNT7A gene, associated with rare limb malformations.
What conditions does this test diagnose?
It diagnoses fibular aplasia or hypoplasia, femoral bowing, and poly-, syn-, and oligodactyly caused by WNT7A gene mutations.
What are the symptoms of WNT7A-related disorders?
Symptoms include shortening of the leg, femoral bowing, missing or extra digits, abnormal curvature, and pain in the affected limb.
How is the test performed?
The test involves analyzing a blood or DNA sample using NGS technology to identify genetic variants.
What sample is required for the test?
A blood sample, extracted DNA, or one drop of blood on an FTA card.
How long does it take to get results?
Results are typically available in 3 to 4 weeks.
What is the cost of the test?
The cost is INR 20000, which includes testing, interpretation, and genetic counseling.
Is home sample collection available?
Yes, free home sample collection is available for online bookings across India.
What does a positive result mean?
A positive result indicates a pathogenic variant in the WNT7A gene, confirming the diagnosis and guiding treatment.
What should I do if I have a family history of these disorders?
Genetic testing and counseling are recommended to assess risk and plan management.
Are there any risks associated with the test?
Risks are minimal, mainly related to blood draw, but genetic results may have psychological implications.
How can I prepare for the test?
Provide clinical history, attend genetic counseling, and ensure proper sample collection as instructed.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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