ZIC5 Gene ZIC5 related brain disorders NGS Genetic Test
Short Name: ZIC5 NGS Genetic Test
Also known as: ZIC5 Gene Mutation Test, ZIC5 Sequencing Test, ZIC5 Disorder NGS Test
ZIC5 Gene ZIC5 related brain disorders NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood, Extracted DNA, or One drop Blood on FTA Card samples. Results in 3 to 4 weeks. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
The purpose of the ZIC5 Gene NGS Genetic Test is to detect pathogenic variants in the ZIC5 gene, aiding in the diagnosis of related brain disorders. It helps confirm clinical suspicions, guide treatment decisions, and facilitate genetic counseling for affected families.
- Test Code
- 2824
- Price
- ₹20,000
- Sample Type
- Blood, Extracted DNA, or One drop Blood on FTA Card
- Result Time
- 3 to 4 weeks
- Fasting Required
- No
- Method
- Next-Generation Sequencing (NGS)
Sample Collection
Provide clinical history of the patient and undergo a genetic counseling session to draw a pedigree chart of affected family members.
Method: Venipuncture or FTA card collection
Laboratory Analysis
Sample collected via venipuncture for blood or using an FTA card for one drop of blood. Procedure is minimally invasive.
Report Delivery
Apply pressure to the collection site to prevent bleeding. Store sample as per instructions before transport.
Timeline: 3 to 4 weeks
Patient Instructions
About This Test
Who Should Get This Test
The purpose of the ZIC5 Gene NGS Genetic Test is to detect pathogenic variants in the ZIC5 gene, aiding in the diagnosis of related brain disorders. It helps confirm clinical suspicions, guide treatment decisions, and facilitate genetic counseling for affected families.
How to Prepare
- Ensure patient is relaxed
- Use sterile equipment
- Label sample correctly with patient details
- Transport at ambient room temperature
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"Early genetic testing for ZIC5 mutations is crucial for timely intervention and management of brain disorders, improving patient outcomes and family counseling."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed or clotted samples
- Incorrect labeling
- Insufficient sample volume
Understanding Your Results
Pathogenic variant detected
Confirms ZIC5-related brain disorder; recommend genetic counseling and clinical management.
No pathogenic variant detected
ZIC5 mutations unlikely; consider other genetic or non-genetic causes.
Variant of uncertain significance
Further evaluation needed; may require family studies or additional testing.
Consult a geneticist or neurologist if symptoms persist, for family planning, or to understand test results and management options.
Limitations
- ⚠May not detect all genetic variants, such as large deletions or duplications
- ⚠Requires genetic counseling for interpretation
- ⚠Results should be correlated with clinical findings
Risks & Considerations
- ●Minimal risk from blood draw, such as bruising or infection
- ●Psychological impact of results; counseling provided
Interfering Factors
- ●Poor sample quality
- ●Contamination during collection
- ●Insufficient DNA quantity
Compare With Similar Tests
| Test | ZIC5 Gene ZIC5 related brain disorders NGS Genetic Test | MECP2 Gene Test | FMR1 Gene Test | Chromosomal Microarray | Whole Exome Sequencing |
|---|---|---|---|---|---|
| Comparison | ZIC5 Gene ZIC5 related brain disorders NGS Genetic Test | For Rett syndrome, different gene focus. | For Fragile X syndrome, distinct disorder. | Detects copy number variants, not specific gene sequencing. | Broader analysis, higher cost, for undiagnosed cases. |
Frequently Asked Questions
What is the ZIC5 Gene NGS Genetic Test?
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How is the sample collected?
Is fasting required before the test?
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We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
Your Data Privacy
Your medical data is protected under Indian law.
✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.
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