Zinc 24 Hour Urine Test
Short Name: Zinc 24h Urine
Also known as: 24-Hour Urine Zinc, Urine Zinc Test, Zinc Excretion Test, 24hr Urine Zinc Level
Zinc 24 Hour Urine Test test available at DNA Labs India for ₹2,106. Uses ICP-MS (Inductively Coupled Plasma Mass Spectrometry) on 24-Hour Urine samples. Results in Reports are typically available the next day after sample receipt. Daily sample collection is accepted, and reports are delivered via online portal, email, and WhatsApp.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Ramarao Paidisetty
Consultant Biochemist · Reg: 21504
Last reviewed: September 7, 2026
Overview
The Zinc 24 Hour Urine Test is ordered to diagnose zinc deficiency or toxicity, to monitor zinc levels in patients receiving zinc supplementation or parenteral nutrition, to investigate the cause of abnormal serum zinc levels, and to assess occupational or environmental zinc exposure. It is also useful in evaluating patients with symptoms suggestive of zinc dysregulation such as unexplained hair loss, impaired wound healing, recurrent infections, growth retardation in children, and taste disturbances. The test helps physicians identify whether abnormal serum zinc is due to dietary insufficiency, malabsorption, excessive renal loss, or excessive zinc ingestion.
- Test Code
- 1469
- CPT Code
- 84630
- ICD Code
- E60
- Price
- ₹2,106
- Sample Type
- 24-Hour Urine
- Result Time
- Reports are typically available the next day after sample receipt. Daily sample collection is accepted, and reports are delivered via online portal, email, and WhatsApp.
- Fasting Required
- No
- Method
- ICP-MS (Inductively Coupled Plasma Mass Spectrometry)
Sample Collection
Patients should avoid sea and freshwater fish for at least 3 days (72 hours) prior to specimen collection. If Gadolinium or Iodine-containing contrast media has been administered, the specimen should not be collected for at least 96 hours. Inform your physician about any zinc supplements, denture adhesives, or medications you are taking. Ensure you have the acid-washed (metal-free) container kit provided by the laboratory. Use powderless gloves during the entire collection process.
Method: 24-Hour Urine Collection
Laboratory Analysis
Begin the 24-hour urine collection by discarding the first morning urine on Day 1. Collect all subsequent urine produced over the next 24 hours in the provided acid-washed (metal-free) container. Store the container refrigerated or on ice during the collection period. On Day 2, collect the first morning urine and add it to the container to complete the 24-hour period. Mix the urine thoroughly. Measure and record the total 24-hour urine volume on the vial and the test request form. Transfer a 10 mL aliquot (minimum 5 mL) to the vial provided in the kit.
Report Delivery
Seal the aliquot vial securely and label it with your name, date, and total urine volume. Ship the sample refrigerated or frozen to the laboratory. The collected specimen should reach the lab as soon as possible to ensure sample integrity. Your report will typically be available the next day after sample receipt.
Timeline: Reports are typically available the next day after sample receipt. Daily sample collection is accepted, and reports are delivered via online portal, email, and WhatsApp.
Patient Instructions
About This Test
Who Should Get This Test
The Zinc 24 Hour Urine Test is ordered to diagnose zinc deficiency or toxicity, to monitor zinc levels in patients receiving zinc supplementation or parenteral nutrition, to investigate the cause of abnormal serum zinc levels, and to assess occupational or environmental zinc exposure. It is also useful in evaluating patients with symptoms suggestive of zinc dysregulation such as unexplained hair loss, impaired wound healing, recurrent infections, growth retardation in children, and taste disturbances. The test helps physicians identify whether abnormal serum zinc is due to dietary insufficiency, malabsorption, excessive renal loss, or excessive zinc ingestion.
How to Prepare
- Use only the acid-washed (metal-free) container kit provided by the laboratory
- Wear powderless gloves throughout the collection process
- Discard the first morning urine on Day 1 and begin collecting from the next void
- Collect all urine over the next 24 hours including the first morning urine on Day 2
- Store the container refrigerated during the entire collection period
- Record the total 24-hour urine volume on the vial and test request form
- Mix urine thoroughly and transfer 10 mL aliquot to the provided vial
- Avoid sea and freshwater fish for 3 days before collection
- Do not collect for 96 hours after Gadolinium or Iodine contrast administration
Doctor's Notes
Reviewed by Dr Ramarao Paidisetty — MBBS, MD (Biochemistry) · Reg. No. 21504
"Zinc is an essential trace element involved in over 300 enzymatic reactions. A 24-hour urine zinc measurement helps clinicians assess zinc homeostasis when serum levels are equivocal or when excessive zinc exposure or renal loss is suspected. This test should always be interpreted alongside serum zinc, dietary history, and clinical symptoms. Patients must use metal-free collection containers and avoid seafood for at least 72 hours before collection to prevent false results. If you experience unexplained hair loss, impaired wound healing, recurrent infections, or taste disturbances, discuss zinc testing with your physician."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Sample collected in non-acid-washed or non-metal-free containers
- Incomplete 24-hour urine collection (no total volume recorded)
- Sample received without proper labeling or requisition form
- Sample collected within 96 hours of Gadolinium or Iodine contrast media administration
- Sample contaminated with blood, stool, or foreign material
- Sample shipped at room temperature exceeding 24 hours
Understanding Your Results
Low urinary zinc excretion may suggest zinc deficiency, poor dietary intake, or malabsorption. Correlate with serum zinc and clinical symptoms. Physicians may recommend dietary modification or zinc supplementation.
Status: Below Normal
Range: Below 150 µg/24 hours
Urinary zinc excretion is within the normal reference range for adults. This suggests adequate zinc status. Continue maintaining a balanced diet rich in zinc-containing foods such as meat, shellfish, legumes, nuts, and seeds.
Status: Normal
Range: 150–1200 µg/24 hours
Elevated urinary zinc excretion may indicate zinc toxicity, excessive zinc supplementation, increased tissue catabolism, or proximal renal tubular dysfunction. Excessive zinc can impair copper absorption leading to hypocupremia. Consult your physician for further evaluation.
Status: Above Normal
Range: Above 1200 µg/24 hours
Consult your physician if your Zinc 24 Hour Urine Test results are outside the normal reference range. Additionally, seek medical advice if you experience symptoms such as persistent hair loss, chronic diarrhoea, unexplained weight loss, frequent infections, slow wound healing, loss of appetite, or impaired taste and smell. Children with growth retardation or delayed sexual development should also be evaluated. If you are on long-term zinc supplementation or parenteral nutrition and your levels are abnormal, your physician may need to adjust your treatment plan.
Limitations
- ⚠A single 24-hour urine zinc measurement may not reflect chronic zinc status; serial measurements may be needed
- ⚠Urine zinc excretion can vary with dietary intake, stress, and physiological state
- ⚠Results must be interpreted alongside serum zinc, serum copper, albumin levels, and clinical presentation
- ⚠The test does not distinguish between dietary zinc insufficiency and malabsorption as causes of deficiency
- ⚠Normal reference ranges may vary slightly between laboratories and populations
Risks & Considerations
- ●No physical risks associated with urine collection
- ●Incorrect timing or incomplete collection may yield inaccurate results and require repeat testing
- ●False results may occur if collection instructions are not followed precisely
Interfering Factors
- ●Recent consumption of sea or freshwater fish within 72 hours of collection may falsely elevate zinc levels
- ●Administration of Gadolinium or Iodine-containing contrast media within 96 hours can interfere with ICP-MS analysis
- ●Use of galvanized or non-acid-washed collection containers can contaminate the sample with exogenous zinc
- ●Zinc-containing supplements, denture adhesives, or topical zinc preparations may affect results
- ●Haemolysis or contamination of urine with blood can lead to falsely elevated results
- ●Incomplete 24-hour urine collection will yield inaccurate results
- ●Use of rubber gloves (instead of powderless gloves) during collection may introduce zinc contamination
Compare With Similar Tests
| Test | Zinc 24 Hour Urine Test | Serum Zinc Test | RBC Zinc Test | Hair Zinc Analysis |
|---|---|---|---|---|
| Comparison | Zinc 24 Hour Urine Test |
Frequently Asked Questions
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