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ACTC1 Gene Cardiomyopathy, dilated type 1R NGS Genetic Test

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ACTC1 Gene Cardiomyopathy, dilated type 1R NGS Genetic Test

Short Name: ACTC1 DCM 1R Test

Also known as: ACTC1-related cardiomyopathy, DCM Type 1R, Alpha-cardiac actin cardiomyopathy

ACTC1 Gene Cardiomyopathy, dilated type 1R NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS), Genetic Sequencing on Blood samples. Results in 3 to 4 Weeks. Free home collection in 300+ cities across India.

NGS Genetic Test🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr Pasupathy Arumugam

Dr Pasupathy Arumugam

Consultant Pathologist · Reg: 21521

Last reviewed: September 7, 2026

Overview

To diagnose mutations in the ACTC1 gene that cause dilated cardiomyopathy type 1R, enabling early intervention, family screening, and personalized treatment plans.

Test Code
5221
Price
₹20,000
Sample Type
Blood
Result Time
3 to 4 Weeks
Fasting Required
No
Method
Next-Generation Sequencing (NGS), Genetic Sequencing
Step 1

Sample Collection

No specific preparation required. Provide clinical history and family pedigree during genetic counseling.

Method: Venipuncture

Step 2

Laboratory Analysis

A blood sample is drawn from a vein in the arm using standard venipuncture techniques.

Step 3

Report Delivery

Apply pressure to the puncture site to prevent bleeding. Resume normal activities unless advised otherwise.

Timeline: 3 to 4 Weeks

Patient Instructions

1
Before the Test:Undergo genetic counseling to understand the test implications and provide family history.
2
During the Test:Blood sample collection; the test involves NGS sequencing in the laboratory.
3
After the Test:Wait for results (3-4 weeks); follow up with a healthcare provider for interpretation and next steps.

About This Test

Who Should Get This Test

To diagnose mutations in the ACTC1 gene that cause dilated cardiomyopathy type 1R, enabling early intervention, family screening, and personalized treatment plans.

How to Prepare

  • Ensure proper identification of the patient
  • Use sterile equipment for blood collection
  • Label the sample correctly with patient details
  • Transport the sample to the lab within the specified stability period

Doctor's Notes

Reviewed by — MBBS, MD (Pathology) · Reg. No. 21521

"Genetic testing for ACTC1 mutations is crucial for early diagnosis, family screening, and personalized management of dilated cardiomyopathy."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood
Sample Volume5-10 mL
ContainerEDTA tube
Collection MethodVenipuncture

Sample Stability

Room temperature24-48 hours
RefrigeratedUp to 7 days
Sample Rejection Criteria:
  • Hemolyzed or clotted samples
  • Insufficient sample volume
  • Incorrect labeling or missing patient information

Understanding Your Results

Results indicate the presence or absence of pathogenic mutations in the ACTC1 gene. A positive result confirms genetic predisposition to dilated cardiomyopathy type 1R.
📊

Positive for pathogenic variant

Confirms diagnosis; recommend genetic counseling and family screening

📊

Negative for pathogenic variant

No mutation detected; clinical correlation needed if symptoms persist

📊

Variant of uncertain significance

Further testing and monitoring may be required

⚠️ When to Consult a Doctor:

Consult a cardiologist or geneticist immediately if you experience symptoms like shortness of breath, chest pain, or if you have a family history of heart disease. After testing, discuss results with a healthcare provider for appropriate management.

Limitations

  • ⚠May not detect all genetic variants or mutations
  • ⚠Results require interpretation by a genetic counselor or specialist
  • ⚠Does not replace clinical evaluation and other diagnostic tests

Risks & Considerations

  • ●Minimal risks from blood draw, such as bruising or infection
  • ●Psychological impact of genetic results, including anxiety
  • ●Potential for incidental findings unrelated to cardiomyopathy

Interfering Factors

  • ●Poor sample quality or contamination
  • ●Recent blood transfusions may affect DNA analysis
  • ●Inadequate sample volume or improper storage

Compare With Similar Tests

TestACTC1 Gene Cardiomyopathy, dilated type 1R NGS Genetic TestTTN Gene Cardiomyopathy TestLMNA Gene Cardiomyopathy TestMYH7 Gene Cardiomyopathy TestCardiac MRI
ComparisonACTC1 Gene Cardiomyopathy, dilated type 1R NGS Genetic Test

Frequently Asked Questions

What is ACTC1 gene cardiomyopathy, dilated type 1R?
It is a rare form of dilated cardiomyopathy caused by mutations in the ACTC1 gene, which affects heart muscle contraction.
How is the ACTC1 gene test performed?
The test uses Next-Generation Sequencing (NGS) to analyze the entire ACTC1 gene from a blood sample.
What is the cost of the ACTC1 gene test in India?
The test costs INR 20,000, with free home sample collection available across India.
Is home sample collection available for this test?
Yes, DNA Labs India offers free home sample collection for online bookings in numerous cities.
How long does it take to get the test results?
Results are typically available within 3 to 4 weeks after sample collection.
What do positive test results mean?
A positive result indicates a pathogenic mutation in the ACTC1 gene, confirming genetic predisposition to dilated cardiomyopathy.
Is genetic counseling required before testing?
Yes, a genetic counseling session is recommended to draw a family pedigree and discuss test implications.
Can this test be used for family screening?
Yes, if a mutation is identified, family members can be tested for early detection and management.
What are the risks of the genetic test?
Risks are minimal, primarily related to blood draw, but psychological impacts of results should be considered.
Is the test covered by insurance schemes like PMJAY?
Coverage varies; it is advisable to check with your insurance provider for specific details.
How accurate is the NGS genetic test for ACTC1?
NGS is highly accurate for detecting mutations, but results should be interpreted in clinical context.
What should I do if I test positive for an ACTC1 mutation?
Consult a cardiologist or geneticist for personalized management, which may include monitoring, medication, or lifestyle changes.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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