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ADGRV1 Gene Febrile seizures, familial, type 4 NGS Genetic Test

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ADGRV1 Gene Febrile seizures, familial, type 4 NGS Genetic Test

Short Name: ADGRV1 FEB4 NGS Test

Also known as: FEB4 Genetic Test, ADGRV1 Mutation Analysis, Familial Febrile Seizures Type 4 Genetic Test

ADGRV1 Gene Febrile seizures, familial, type 4 NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS), Genetic Sequencing on Blood samples. Results in 3 to 4 Weeks. Free home collection in 300+ cities across India.

NGS Genetic TestPediatric and All Ages🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr SULOCHANA HEMCHANDRA HOLLA

Dr SULOCHANA HEMCHANDRA HOLLA

Consultant Medical Geneticist · Reg: 8532

Last reviewed: September 7, 2026

Overview

The purpose of this test is to detect pathogenic mutations in the ADGRV1 gene for the diagnosis of familial febrile seizures type 4, aiding in clinical management, family planning, and genetic counselling.

Test Code
1608
Price
₹20,000
Sample Type
Blood
Result Time
3 to 4 Weeks
Fasting Required
No
Method
Next-Generation Sequencing (NGS), Genetic Sequencing
Step 1

Sample Collection

A genetic counselling session to draw a pedigree chart of family members affected with FEB4. Provide clinical history of the patient.

Method: Venipuncture

Step 2

Laboratory Analysis

Blood sample collection via venipuncture by a trained phlebotomist. No fasting required.

Step 3

Report Delivery

Apply pressure to the puncture site to prevent bruising. Sample is processed in the laboratory for NGS analysis.

Timeline: 3 to 4 Weeks

Patient Instructions

1
Before the Test:Genetic counselling and clinical history review are required before testing.
2
During the Test:Blood sample is drawn and sent for NGS analysis in the laboratory.
3
After the Test:Results are available in 3-4 weeks, followed by a counselling session to discuss findings.

About This Test

Who Should Get This Test

The purpose of this test is to detect pathogenic mutations in the ADGRV1 gene for the diagnosis of familial febrile seizures type 4, aiding in clinical management, family planning, and genetic counselling.

How to Prepare

  • Ensure patient identification is correct
  • Use aseptic technique for blood draw
  • Label the sample properly
  • Transport to lab at ambient room temperature

Doctor's Notes

Reviewed by — MBBS, MD (Medical Genetics) · Reg. No. 8532

"This genetic test aids in diagnosing familial febrile seizures, supporting family planning and early intervention strategies."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood
Sample VolumeAs required
ContainerEDTA Tube
Collection MethodVenipuncture

Sample Stability

Store blood at 2-8°C if delayed
Process within 24 hours for optimal results
Sample Rejection Criteria:
  • Hemolyzed or lipemic sample
  • Insufficient sample volume
  • Incorrectly labeled sample
  • Contaminated sample

Understanding Your Results

Results indicate the presence or absence of mutations in the ADGRV1 gene. Positive results confirm a genetic basis for febrile seizures, while negative results may require further testing.
Positive for pathogenic variant: Confirms diagnosis of FEB4, consider family screening
Negative result: Does not rule out other genetic or non-genetic causes
Variant of uncertain significance (VUS): Requires additional evaluation and family studies
⚠️ When to Consult a Doctor:

Consult a doctor if seizures persist, worsen, or are accompanied by developmental delays. Seek genetic counselling for family planning and management guidance.

Limitations

  • ⚠May not detect all genetic variants or mutations
  • ⚠Requires genetic counselling for interpretation
  • ⚠Not a standalone diagnostic tool; clinical correlation is needed

Risks & Considerations

  • ●Minimal risk from blood draw, such as slight pain or bruising
  • ●Possible anxiety from test results

Interfering Factors

  • ●Contaminated or degraded DNA sample
  • ●Hemolyzed blood sample
  • ●Improper sample storage or handling

Compare With Similar Tests

TestADGRV1 Gene Febrile seizures, familial, type 4 NGS Genetic Test
ComparisonADGRV1 Gene Febrile seizures, familial, type 4 NGS Genetic Test

Frequently Asked Questions

What is the ADGRV1 Gene Febrile Seizures Test?
It is an NGS genetic test to detect mutations in the ADGRV1 gene, associated with familial febrile seizures type 4 (FEB4).
Who should consider this test?
Children with recurrent febrile seizures, family history of FEB4, or associated symptoms like developmental delay.
How is the test performed?
A blood sample is collected and analyzed using next-generation sequencing to identify genetic mutations.
What is the cost of the test in India?
The test costs INR 20,000, with free home sample collection available across India.
How long does it take to get results?
Results are typically available within 3 to 4 weeks after sample collection.
Is home collection available?
Yes, free home sample collection is offered for online bookings in many cities across India.
What are the symptoms of Familial Febrile Seizures Type 4?
Main symptoms include recurrent febrile seizures, developmental delay, intellectual disability, and sometimes autism spectrum disorder.
How accurate is the genetic test?
The test uses NGS technology for high accuracy in detecting mutations, but clinical correlation is essential.
What do positive test results mean?
Positive results confirm a genetic mutation in ADGRV1, indicating FEB4, which can guide treatment and family counselling.
Is genetic counselling provided?
Yes, a genetic counselling session is included to draw a pedigree chart and discuss implications.
Are there any risks or side effects?
Risks are minimal, limited to potential bruising from blood draw; emotional impact from results may occur.
How should I prepare for the test?
No special preparation is needed, but provide clinical history and undergo pre-test genetic counselling.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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