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AFF3 Gene Rheumatoid arthritis, susceptibility to NGS Genetic Test

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AFF3 Gene Rheumatoid arthritis, susceptibility to NGS Genetic Test

Also known as: AFF3 Gene RA Susceptibility Test, Rheumatoid Arthritis Genetic Test

AFF3 Gene Rheumatoid arthritis, susceptibility to NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses NGS on Blood samples. Results in 3 to 4 Weeks. Free home collection in 300+ cities across India.

NGS Genetic Test🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr Pasupathy Arumugam

Dr Pasupathy Arumugam

Consultant Pathologist · Reg: 21521

Last reviewed: September 7, 2026

Overview

The purpose of the AFF3 Gene Rheumatoid Arthritis Susceptibility NGS Genetic Test is to identify genetic variations in the AFF3 gene that may increase an individual's risk of developing rheumatoid arthritis, enabling early risk assessment and personalized healthcare planning.

Test Code
2463
Price
₹20,000
Sample Type
Blood
Result Time
3 to 4 Weeks
Fasting Required
No
Method
NGS
Step 1

Sample Collection

Provide clinical history and undergo genetic counseling to draw a pedigree chart of family members affected with rheumatoid arthritis or related conditions.

Method: Blood draw

Step 2

Laboratory Analysis

A small blood sample is collected via venipuncture by a trained phlebotomist.

Step 3

Report Delivery

Apply pressure to the puncture site to prevent bruising; resume normal activities unless otherwise advised.

Timeline: 3 to 4 Weeks

Patient Instructions

1
Before the Test:Provide clinical history and undergo genetic counseling to draw a pedigree chart of family members affected with rheumatoid arthritis or related conditions.
2
During the Test:A small blood sample is collected via venipuncture by a trained phlebotomist.
3
After the Test:Apply pressure to the puncture site to prevent bruising; resume normal activities unless otherwise advised.

About This Test

Who Should Get This Test

The purpose of the AFF3 Gene Rheumatoid Arthritis Susceptibility NGS Genetic Test is to identify genetic variations in the AFF3 gene that may increase an individual's risk of developing rheumatoid arthritis, enabling early risk assessment and personalized healthcare planning.

How to Prepare

  • No special preparation required
  • Bring valid ID and doctor's prescription if available
  • Inform staff of any medications or health conditions

Doctor's Notes

Reviewed by — MBBS, MD (Pathology) · Reg. No. 21521

"Early genetic testing for AFF3 gene variants can aid in personalized risk assessment and management strategies for rheumatoid arthritis."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood
Collection MethodBlood draw

Understanding Your Results

Results indicate the presence or absence of genetic variations in the AFF3 gene associated with rheumatoid arthritis susceptibility.
📊

Positive for pathogenic variants

Increased genetic susceptibility to rheumatoid arthritis; recommend consultation with a rheumatologist for further evaluation.

📊

Negative for pathogenic variants

No increased genetic susceptibility detected based on current knowledge; however, RA risk may involve other factors.

⚠️ When to Consult a Doctor:

Consult a doctor if you experience symptoms of rheumatoid arthritis, have a family history of the disease, or receive a positive genetic test result for risk assessment and management.

Risks & Considerations

  • ●Minor bruising or discomfort at the blood draw site
  • ●Rare risk of infection or fainting

Frequently Asked Questions

What is the AFF3 gene?
The AFF3 gene is located on chromosome 2 and plays a role in regulating the immune system. Variations in this gene have been linked to increased susceptibility to rheumatoid arthritis.
How is the NGS Genetic Test performed?
The test involves collecting a small blood or saliva sample, which is analyzed using Next-Generation Sequencing technology to identify genetic variations in the AFF3 gene.
What does a positive test result mean?
A positive result indicates the presence of genetic variations in the AFF3 gene that may increase your risk of developing rheumatoid arthritis, but it does not diagnose the disease.
Is the test painful?
The test involves a standard blood draw, which may cause minor discomfort or bruising, but it is generally not painful.
How long does it take to get results?
Results are typically available within 3 to 4 weeks after sample collection.
Is home sample collection available?
Yes, DNA Labs India offers free home sample collection for this test across many cities in India.
What is the cost of the test?
The test costs INR 20000.0, with a special discounted price available for online bookings.
Who should consider taking this test?
Individuals with a family history of rheumatoid arthritis, symptoms of joint issues, or those interested in genetic risk assessment for RA.
Can this test diagnose rheumatoid arthritis?
No, this test assesses genetic susceptibility only. Diagnosis of RA requires clinical evaluation, imaging, and blood tests for antibodies like RF and anti-CCP.
What are the risks of the test?
Risks are minimal and include minor bruising or discomfort from the blood draw. Serious complications are rare.
How accurate is the NGS Genetic Test?
The test uses advanced sequencing technology for high accuracy in detecting genetic variations, but results should be interpreted in conjunction with clinical assessment.
What should I do after receiving the results?
Consult a healthcare provider, such as a rheumatologist or genetic counselor, to discuss the results and appropriate next steps for risk management or treatment.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

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Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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