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DNA Labs India

Alpha-1-Antitrypsin Quantitation (AAT) Test

DNA Labs India | ISO 9001:2015 Certified

Alpha-1-Antitrypsin Quantitation (AAT) Test

Short Name: AAT Test

Also known as: Alpha-1-Antitrypsin Test, AAT Quantitation Test

Alpha-1-Antitrypsin Quantitation (AAT) Test test available at DNA Labs India for ₹3,000. Uses Nephelometry on Serum samples. Results in Reports are available on the same day for samples received by 4 PM on Monday or Thursday.. Free home collection in 300+ cities across India.

Blood TestAll Ages🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr SULOCHANA HEMCHANDRA HOLLA

Dr SULOCHANA HEMCHANDRA HOLLA

Consultant Medical Geneticist · Reg: 8532

Last reviewed: September 7, 2026

Overview

To diagnose Alpha-1-Antitrypsin deficiency by measuring AAT levels in the blood, aiding in the assessment of lung and liver health.

Test Code
85
Price
₹3,000
Sample Type
Serum
Result Time
Reports are available on the same day for samples received by 4 PM on Monday or Thursday.
Fasting Required
No
Method
Nephelometry
Step 1

Sample Collection

No special preparation required.

Method: Venipuncture

Step 2

Laboratory Analysis

A blood sample will be drawn from a vein in your arm by a trained phlebotomist.

Step 3

Report Delivery

Apply pressure to the puncture site with a cotton ball to stop bleeding. You may resume normal activities immediately.

Timeline: Reports are available on the same day for samples received by 4 PM on Monday or Thursday.

Patient Instructions

1
Before the Test:No fasting or special preparation is required before the test.
2
During the Test:The test involves a simple blood draw that takes a few minutes. You may feel a slight prick during needle insertion.
3
After the Test:You can resume normal activities immediately. There is no downtime.

About This Test

Who Should Get This Test

To diagnose Alpha-1-Antitrypsin deficiency by measuring AAT levels in the blood, aiding in the assessment of lung and liver health.

How to Prepare

  • Use 1 Red Top (No Additive) tube
  • Collect 2 mL blood (0.5 mL minimum)
  • Separate serum from cells immediately after collection
  • Ship refrigerated or frozen as per stability guidelines

Doctor's Notes

Reviewed by — MBBS, MD (Medical Genetics) · Reg. No. 8532

"Early diagnosis of Alpha-1-Antitrypsin deficiency is essential for initiating appropriate management and preventing irreversible lung and liver damage."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeSerum
Sample Volume2 mL (0.5 mL min.)
ContainerRed Top (No Additive) tube
Collection MethodVenipuncture

Sample Stability

Room Temperature: Not stable
Refrigerated (2-8°C): 3 days
Frozen (-20°C): 3 months
Sample Rejection Criteria:
  • Hemolyzed or lipemic samples
  • Improperly labeled or contaminated specimens
  • Insufficient sample volume
  • Use of SST gel barrier tubes

Understanding Your Results

Results of the AAT test indicate the level of alpha-1-antitrypsin in your blood, which helps in diagnosing AAT deficiency.
Low AAT levels (below normal range) may indicate AAT deficiency, increasing risk for lung and liver disease.
Normal levels suggest adequate production of AAT and lower likelihood of deficiency.
Elevated levels may occur in acute inflammation, pregnancy, or other conditions, and require clinical correlation.
⚠️ When to Consult a Doctor:

If you experience symptoms like persistent cough, shortness of breath, or jaundice, or if your test results are abnormal, consult your physician for further evaluation and management.

Limitations

  • ⚠Does not specify the genetic variant causing deficiency
  • ⚠May require confirmation with genetic testing or phenotyping
  • ⚠Not a standalone diagnostic for lung or liver disease

Risks & Considerations

  • ●Minor bruising or pain at the puncture site
  • ●Rarely, infection or excessive bleeding
  • ●Dizziness or lightheadedness during blood draw

Interfering Factors

  • ●Acute inflammation or infection may elevate AAT levels
  • ●Liver disease can affect AAT production
  • ●Certain medications may influence results

Frequently Asked Questions

What is the Alpha-1-Antitrypsin Quantitation Test?
It is a blood test that measures the level of alpha-1-antitrypsin protein, which is important for protecting the lungs and liver.
Why is the AAT test recommended?
It is recommended to diagnose AAT deficiency, a genetic condition that can lead to lung and liver damage, especially if you have symptoms or a family history.
How is the AAT test performed?
A small blood sample is drawn from your vein, and the AAT level is measured using nephelometry in a laboratory.
What does a low AAT level indicate?
Low AAT levels may indicate AAT deficiency, increasing the risk for conditions like emphysema and liver disease.
Is fasting required for the AAT test?
No, fasting is not required. No special preparation is needed before the test.
How much does the AAT test cost at DNA Labs India?
The test costs INR 3000, which includes home sample collection and report delivery.
Is home sample collection available for this test?
Yes, DNA Labs India offers free home sample collection for online bookings across many cities in India.
How long does it take to get the test results?
Results are typically available on the same day for samples received by 4 PM on Monday or Thursday.
What are the symptoms of AAT deficiency?
Symptoms include shortness of breath, wheezing, chronic cough, frequent lung infections, jaundice, and swelling in the abdomen.
Can AAT deficiency be treated?
While there is no cure, treatments like augmentation therapy and lifestyle changes can manage symptoms and slow progression.
Is the AAT test covered by insurance?
Coverage varies by insurance plan. It is advisable to check with your provider or insurer for specific details.
How accurate is the AAT test?
The test is accurate when performed in accredited labs, but results should be interpreted by a healthcare professional in clinical context.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

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✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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