Anti NMO (Neuromyelitis Optica) Panel CSF Test
Short Name: Anti NMO Panel CSF Test
Also known as: Aquaporin-4 Antibody Test, NMO-IgG Test, Anti-MOG Antibody Test
Anti NMO (Neuromyelitis Optica) Panel CSF Test test available at DNA Labs India for ₹9,000. Uses Cell based assay, Immunofluorescence assay (IFA) on Cerebrospinal Fluid (CSF) samples. Results in Reports are available on the same day if the sample is received by Tuesday or Friday by 9 am.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SHAILAJA RAGHUNATH MURDESHWAR
Consultant Physician · Reg: 8052
Last reviewed: September 7, 2026
Overview
To detect the presence of Anti-Aquaporin-4 (AQP4) and Anti-Myelin Oligodendrocyte Glycoprotein (MOG) antibodies in cerebrospinal fluid for the diagnosis of Neuromyelitis Optica and related disorders.
- Test Code
- 149
- Price
- ₹9,000
- Sample Type
- Cerebrospinal Fluid (CSF)
- Result Time
- Reports are available on the same day if the sample is received by Tuesday or Friday by 9 am.
- Fasting Required
- No
- Method
- Cell based assay, Immunofluorescence assay (IFA)
Sample Collection
No special preparation required. Inform your doctor about any medications, medical conditions, or recent procedures.
Method: Lumbar puncture
Laboratory Analysis
CSF sample is collected via lumbar puncture by a trained healthcare professional under sterile conditions.
Report Delivery
Rest for a few hours post-procedure to minimize the risk of headache. Monitor the puncture site for signs of infection and report any unusual symptoms.
Timeline: Reports are available on the same day if the sample is received by Tuesday or Friday by 9 am.
Patient Instructions
About This Test
Who Should Get This Test
To detect the presence of Anti-Aquaporin-4 (AQP4) and Anti-Myelin Oligodendrocyte Glycoprotein (MOG) antibodies in cerebrospinal fluid for the diagnosis of Neuromyelitis Optica and related disorders.
How to Prepare
- Sample must be collected in a sterile, screw-capped container
- Ship refrigerated or frozen to maintain sample stability
- Minimum volume required is 0.5 mL of cerebrospinal fluid
Doctor's Notes
Reviewed by Dr SHAILAJA RAGHUNATH MURDESHWAR — MBBS, MD (General Medicine) · Reg. No. 8052
"Anti NMO Panel CSF Test is essential for accurate diagnosis of Neuromyelitis Optica, helping to distinguish it from Multiple Sclerosis and guide appropriate immunotherapy."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed sample
- Insufficient sample volume
- Improper container or storage conditions
Understanding Your Results
Positive for Anti-AQP4 Antibody
Highly suggestive of Neuromyelitis Optica. Correlate with clinical symptoms and imaging studies for confirmation.
Positive for Anti-MOG Antibody
Associated with MOG antibody disease, which may present with similar features to NMO. Further evaluation recommended.
Negative for both antibodies
NMO is less likely, but clinical assessment is essential to rule out other conditions like Multiple Sclerosis.
Consult a neurologist if you experience symptoms such as sudden vision loss, limb weakness, severe sensory changes, or bladder/bowel dysfunction, especially if recurrent or worsening.
Limitations
- ⚠False negatives may occur in early disease stages
- ⚠Test does not distinguish between active and past infection
- ⚠Results should be interpreted in conjunction with clinical findings and other diagnostic tests
Risks & Considerations
- ●Post-lumbar puncture headache
- ●Infection at the puncture site
- ●Bleeding or nerve damage (rare)
- ●Low back pain or stiffness
Interfering Factors
- ●Hemolyzed or lipemic samples may affect results
- ●Recent infections or immunosuppressive therapy could influence antibody levels
Compare With Similar Tests
| Test | Anti NMO (Neuromyelitis Optica) Panel CSF Test | Anti NMO Antibody Serum Test | Multiple Sclerosis Panel | MRI Brain and Spine | CSF Analysis for Cell Count and Protein |
|---|---|---|---|---|---|
| Comparison | Anti NMO (Neuromyelitis Optica) Panel CSF Test | Uses a blood sample instead of CSF, which may be less invasive but CSF testing can offer higher specificity for central nervous system involvement. | Helps differentiate NMO from MS by detecting distinct antibody profiles and clinical patterns. | Imaging study to visualize inflammation in optic nerves and spinal cord, often used alongside antibody tests for comprehensive diagnosis. | Provides general information on CSF composition but lacks specificity for NMO antibodies. |
Frequently Asked Questions
What is Neuromyelitis Optica (NMO)?
What does the Anti NMO Panel CSF Test detect?
How is the test performed?
What is the cost of the test at DNA Labs India?
Is home sample collection available?
What are the symptoms that indicate the need for this test?
How should I prepare for the test?
When will I receive the report?
What does a positive result mean?
Can this test differentiate NMO from Multiple Sclerosis?
Are there any risks associated with CSF collection?
How accurate is the test?
Related Tests
Reference Laboratory Services
We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
Your Data Privacy
Your medical data is protected under Indian law.
✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.
Book Your Test
Enter your details and we'll connect you within 15 minutes.