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DNA Labs India

Autoimmune Encephalitis Panel CSF Test

DNA Labs India | ISO 9001:2015 Certified

Autoimmune Encephalitis Panel CSF Test

Short Name: Autoimmune Encephalitis Panel CSF

Also known as: Autoimmune Encephalitis Antibody Panel CSF, AE Panel CSF Test

Autoimmune Encephalitis Panel CSF Test test available at DNA Labs India for ₹24,000. Uses Cell Based Assay, Immunofluorescence Assay (IFA) on CSF (Cerebrospinal Fluid) samples. Results in Reports are typically available same day if sample is received by Tuesday or Friday by 9 AM.. Free home collection in 300+ cities across India.

Diagnostic Test🏠 Home Collection

Overview

The purpose of the Autoimmune Encephalitis Panel CSF Test is to detect specific antibodies in cerebrospinal fluid that are indicative of autoimmune encephalitis. These antibodies include: NMDA (N-methyl-D-aspartate), AMPA (α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid) with GLUR 1 and GLUR 2 subunits, GABA-B (gamma-aminobutyric acid B), LG1 (leucine-rich glioma-inactivated 1), and CASPR2 (contactin-associated protein-like 2). Identification of these antibodies aids in confirming the diagnosis, differentiating between types of autoimmune encephalitis, and guiding appropriate immunotherapy treatments.

Test Code
183
Price
₹24,000
Sample Type
CSF (Cerebrospinal Fluid)
Result Time
Reports are typically available same day if sample is received by Tuesday or Friday by 9 AM.
Fasting Required
No
Method
Cell Based Assay, Immunofluorescence Assay (IFA)
Step 1

Sample Collection

No special preparation required. Inform the healthcare provider about any medications or medical history.

Method: CSF Collection via Lumbar Puncture

Step 2

Laboratory Analysis

CSF is collected via lumbar puncture performed by a trained healthcare professional. The procedure involves inserting a needle into the lower spine to extract fluid.

Step 3

Report Delivery

Store the sample as instructed—ship refrigerated or frozen. Monitor for any post-procedure symptoms like headache.

Timeline: Reports are typically available same day if sample is received by Tuesday or Friday by 9 AM.

Patient Instructions

1
Before the Test:No fasting required. Inform your doctor about all medications and allergies. Discuss the procedure and risks with your healthcare provider.
2
During the Test:The lumbar puncture is performed under sterile conditions. You may experience mild discomfort or pressure during the procedure.
3
After the Test:Rest for a few hours post-procedure. Stay hydrated and monitor for side effects like headache, nausea, or back pain. Seek medical help if severe symptoms occur.

About This Test

Who Should Get This Test

The purpose of the Autoimmune Encephalitis Panel CSF Test is to detect specific antibodies in cerebrospinal fluid that are indicative of autoimmune encephalitis. These antibodies include: NMDA (N-methyl-D-aspartate), AMPA (α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid) with GLUR 1 and GLUR 2 subunits, GABA-B (gamma-aminobutyric acid B), LG1 (leucine-rich glioma-inactivated 1), and CASPR2 (contactin-associated protein-like 2). Identification of these antibodies aids in confirming the diagnosis, differentiating between types of autoimmune encephalitis, and guiding appropriate immunotherapy treatments.

How to Prepare

  • Collect 1 mL CSF (minimum 0.5 mL) in a sterile screw-capped container
  • Ship sample refrigerated or frozen to maintain stability
  • Ensure proper labeling and documentation

Doctor's Notes

"This test is essential for diagnosing autoimmune encephalitis, which can present with diverse neurological symptoms like memory loss, seizures, and behavioral changes. Early detection via antibody testing in CSF improves treatment outcomes."

Test Parameters & Specifications

Sample TypeCSF (Cerebrospinal Fluid)
Sample Volume1 mL (0.5 mL min)
ContainerSterile screw capped container
Collection MethodCSF Collection via Lumbar Puncture

Sample Stability

Room Temperature: 6 hours
Refrigerator: 1 week
Frozen: 2 weeks
Sample Rejection Criteria:
  • Insufficient sample volume
  • Contaminated or hemolyzed sample
  • Improper container or storage conditions

Understanding Your Results

Results of the Autoimmune Encephalitis Panel CSF Test indicate the presence or absence of specific antibodies in cerebrospinal fluid. Positive results suggest autoimmune encephalitis and help identify the subtype, while negative results do not completely rule out the condition and require clinical correlation.
Positive for NMDA antibody: Suggests anti-NMDA receptor encephalitis
Positive for AMPA antibodies: Indicates AMPA receptor encephalitis
Positive for GABA-B antibody: Associated with GABA-B receptor encephalitis
Positive for LG1 or CASPR2 antibodies: Suggests LGI1 or CASPR2 antibody-related disorders
Negative results: May require repeat testing or additional diagnostics if symptoms persist
⚠️ When to Consult a Doctor:

Consult a neurologist immediately if symptoms like memory loss, seizures, or behavioral changes occur. For positive test results, follow up for treatment planning.

Limitations

  • May not detect all subtypes of autoimmune encephalitis
  • Results require correlation with clinical symptoms and other diagnostic tests
  • False negatives possible in early disease stages

Risks & Considerations

  • Headache (post-lumbar puncture)
  • Infection at puncture site
  • Bleeding or nerve damage (rare)
  • Back pain or soreness

Interfering Factors

  • Sample hemolysis or contamination
  • Improper storage or transport of CSF
  • Recent infections or vaccinations may affect antibody levels

Compare With Similar Tests

TestAutoimmune Encephalitis Panel CSF TestEEG (Electroencephalogram)MRI BrainBlood Antibody PanelLumbar Puncture with CSF Analysis
ComparisonAutoimmune Encephalitis Panel CSF Test

Frequently Asked Questions

What is the Autoimmune Encephalitis Panel CSF Test?
This test detects specific antibodies in cerebrospinal fluid (CSF) to diagnose autoimmune encephalitis, a neurological disorder where the immune system attacks brain cells.
What symptoms indicate the need for this test?
Symptoms include memory loss, seizures, behavioral changes, speech difficulties, muscle weakness, visual disturbances, and fever. Consult a neurologist if these occur.
How is the test performed?
The test involves collecting CSF via lumbar puncture and analyzing it for antibodies like NMDA, AMPA, GABA-B, LG1, and CASPR2 using cell-based assay and IFA methods.
What is the cost of the test in India?
The cost is INR 24000 at DNA Labs India, with free home sample collection available across many cities.
Is the test covered by insurance?
Coverage varies by insurance provider and policy. Check with your insurer or government healthcare programs like PMJAY or CGHS for eligibility.
How should I prepare for the test?
No special preparation is required. Inform your doctor about medications and medical history before the procedure.
What are the risks of the lumbar puncture?
Risks include headache, infection, bleeding, or back pain. These are generally rare and manageable with medical care.
How long does it take to get results?
Results are typically available same day if the sample is received on Tuesday or Friday by 9 AM.
What do positive results mean?
Positive results indicate the presence of specific antibodies, suggesting autoimmune encephalitis. This helps determine the subtype and guide treatment.
Can negative results rule out autoimmune encephalitis?
No, negative results do not completely rule out the condition. Clinical correlation and repeat testing may be needed if symptoms persist.
Where can I get this test done?
The test is available at DNA Labs India with home collection in numerous cities including Mumbai, Delhi, Bangalore, Hyderabad, and more across India.
What is the sample stability for CSF?
CSF samples are stable at room temperature for 6 hours, in the refrigerator for 1 week, and frozen for 2 weeks.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

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Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

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