APO E Genotyping Test
Also known as: Apolipoprotein E Genotyping, APOE Test, APO E Genetic Test
APO E Genotyping Test test available at DNA Labs India for ₹38,000. Uses PCR Hybridization on Whole blood samples. Results in 10 working days from sample collection. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
The primary purpose of the APO E Genotyping Test is to identify genetic variants in the APO E gene that may increase an individual's risk of developing Alzheimer's disease, cardiovascular disorders, and diabetes. This information supports early diagnosis, risk assessment, and personalized medical management.
- Test Code
- 160
- Price
- ₹38,000
- Sample Type
- Whole blood
- Result Time
- 10 working days from sample collection
- Fasting Required
- No
- Method
- PCR Hybridization
Sample Collection
Duly filled Genomics Clinical Information Requisition Form (Form 20) is mandatory. No fasting required. Inform the lab of any recent medications or blood transfusions.
Method: Venipuncture
Laboratory Analysis
A blood sample of 4 mL will be drawn from a vein in the arm using a sterile needle and collected in an EDTA tube. The process is quick and minimally invasive.
Report Delivery
Apply pressure to the puncture site to prevent bleeding. The sample is refrigerated and shipped to the laboratory for analysis.
Timeline: 10 working days from sample collection
Patient Instructions
About This Test
Who Should Get This Test
The primary purpose of the APO E Genotyping Test is to identify genetic variants in the APO E gene that may increase an individual's risk of developing Alzheimer's disease, cardiovascular disorders, and diabetes. This information supports early diagnosis, risk assessment, and personalized medical management.
How to Prepare
- Use a Lavender top (EDTA) tube for collection
- Collect 4 mL whole blood (2 mL minimum)
- Ship refrigerated; do not freeze
- Ensure the Genomics Clinical Information Requisition Form is completed
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"This test is vital for identifying genetic predispositions to neurological and metabolic disorders, aiding in early intervention and personalized healthcare."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Insufficient sample volume
- Wrong collection tube or improper labeling
- Sample hemolysis or clotting
- Missing or incomplete requisition form
Understanding Your Results
ε3/ε3
Most common genotype with no significantly elevated risk for Alzheimer's or cardiovascular disease.
ε3/ε4
Associated with higher risk for Alzheimer's disease and cardiovascular issues compared to ε3/ε3.
ε4/ε4
Significantly elevates risk for early-onset Alzheimer's disease and coronary artery disease.
ε2/ε2
May offer some protection against Alzheimer's disease but could be linked to other lipid metabolism disorders.
ε2/ε3
Generally associated with reduced risk for Alzheimer's disease.
ε2/ε4
Risk profile may be intermediate; consult a healthcare provider for personalized interpretation.
Consult a doctor if results indicate high-risk genotypes (e.g., ε4/ε4), especially with symptoms like memory loss, high cholesterol, or family history of Alzheimer's or heart disease. Genetic counseling is recommended for interpretation and planning.
Limitations
- ⚠This test indicates genetic risk, not a definitive diagnosis of disease
- ⚠Results should be interpreted in conjunction with clinical history and other diagnostic tests
- ⚠Does not screen for all genetic factors related to Alzheimer's or cardiovascular diseases
- ⚠Ethical considerations regarding genetic information and privacy
Risks & Considerations
- ●Minor bruising or discomfort at the blood draw site
- ●Rare risk of infection or hematoma
- ●Potential anxiety from genetic risk information
Interfering Factors
- ●Hemolyzed or lipemic blood samples
- ●Improper sample storage or handling
- ●Recent blood transfusions
- ●Contamination during collection
Frequently Asked Questions
What is the APO E Genotyping Test?
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How is the test performed?
What do the results indicate?
Is the test painful?
How long does it take to get results?
Is fasting required for this test?
Can this test diagnose Alzheimer's disease?
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Is home collection available?
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We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
Your Data Privacy
Your medical data is protected under Indian law.
✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.
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