APP Gene Cerebral Amyloid Angiopathy, APP Related NGS Genetic Test
Short Name: APP Gene CAA NGS Test
Also known as: APP Gene Mutation Test, CAA Genetic Test, APP Gene NGS Panel
APP Gene Cerebral Amyloid Angiopathy, APP Related NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses NGS Technology on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 weeks from sample receipt. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Pasupathy Arumugam
Consultant Pathologist · Reg: 21521
Last reviewed: September 7, 2026
Overview
The purpose of this test is to identify mutations in the APP gene that are associated with cerebral amyloid angiopathy. It aids in confirming a clinical diagnosis, evaluating genetic predisposition, and enabling informed decision making for patients and families.
- Test Code
- 3947
- ICD Code
- I68.0
- Price
- ₹20,000
- Sample Type
- Blood or Extracted DNA or One drop Blood on FTA Card
- Result Time
- 3 to 4 weeks from sample receipt
- Fasting Required
- No
- Method
- NGS Technology
Sample Collection
No fasting required. A genetic counselling session is recommended to draw a pedigree chart of family members affected with CAA or other neurological disorders.
Method: Venipuncture or Dried Blood Spot
Laboratory Analysis
A small amount of blood will be drawn from a vein in your arm, or a few drops of blood will be placed on an FTA card for dried blood spot analysis.
Report Delivery
You can resume normal activities. There are no restrictions after the sample collection.
Timeline: 3 to 4 weeks from sample receipt
Patient Instructions
About This Test
Who Should Get This Test
The purpose of this test is to identify mutations in the APP gene that are associated with cerebral amyloid angiopathy. It aids in confirming a clinical diagnosis, evaluating genetic predisposition, and enabling informed decision making for patients and families.
How to Prepare
- Please carry a government-issued photo ID
- Provide detailed clinical history and family pedigree
- Inform the lab if you have received a blood transfusion or bone marrow transplant in the past 3 months
Doctor's Notes
Reviewed by Dr Pasupathy Arumugam — MBBS, MD (Pathology) · Reg. No. 21521
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Sample received in improper container
- Insufficient sample quantity
- Sample leaking or unstable
Understanding Your Results
No pathogenic variant detected
Negative for known pathogenic mutations in the APP gene. Risk of APP-related CAA is not elevated based on this gene.
Pathogenic variant detected
Presence of a disease-causing mutation; increased risk for cerebral amyloid angiopathy.
Variant of uncertain significance (VUS)
A genetic change with unclear impact on disease. Further testing of family members may be needed.
Consult a neurologist or clinical geneticist if you have symptoms such as recurrent lobar haemorrhage, unexplained headaches, cognitive decline, or a family history of CAA.
Limitations
- ⚠This test is not intended for prenatal screening
- ⚠May not detect large deletions, insertions, or structural rearrangements
- ⚠A negative result does not exclude all forms of CAA, as other genes or factors may be involved
- ⚠Variants of uncertain significance may require additional family studies
Risks & Considerations
- ●Minor bruising at the injection site
- ●Dizziness or lightheadedness during blood draw
- ●Potential psychological distress from test result
Interfering Factors
- ●Recent bone marrow transplant or allogeneic stem cell transplant
- ●Blood transfusion within the past 3 months may affect DNA analysis
- ●Contaminated or hemolyzed blood samples
Frequently Asked Questions
What is the cost of the APP gene CAA NGS genetic test?
What is the purpose of this test?
Who should consider taking this test?
How is the sample collected?
Do I need to fast before the test?
What is the turnaround time?
How will I receive my report?
Can a positive result confirm I have CAA?
What are the limitations of this test?
Is the test covered by insurance?
Is home sample collection available?
How do I book the test?
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We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
Your Data Privacy
Your medical data is protected under Indian law.
✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.
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