ARHGEF10 Gene Slowed nerve conduction velocity, autosomanal dominant NGS Genetic Test
Short Name: ARHGEF10 Gene NGS Test
Also known as: ARHGEF10 gene mutation analysis, ARHGEF10 sequencing, Autosomal dominant NGS genetic test for ARHGEF10, Slow nerve conduction velocity genetic test
ARHGEF10 Gene Slowed nerve conduction velocity, autosomanal dominant NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in Reports are typically available within 3 to 4 weeks from the date the sample is received at the laboratory.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
To identify pathogenic mutations in the ARHGEF10 gene associated with autosomal dominant slowed nerve conduction velocity, aiding in diagnosis, prognosis, and genetic counseling.
- Test Code
- 4505
- Price
- ₹20,000
- Sample Type
- Blood or Extracted DNA or One drop Blood on FTA Card
- Result Time
- Reports are typically available within 3 to 4 weeks from the date the sample is received at the laboratory.
- Fasting Required
- No
- Method
- Next Generation Sequencing (NGS)
Sample Collection
No fasting is required. Please drink adequate water before sample collection. A genetic counseling session is recommended prior to testing.
Method: Blood draw or FTA card spot
Laboratory Analysis
Blood sample collection takes about 5 minutes. For FTA card, follow the provided instructions carefully.
Report Delivery
No specific precautions are required after sample collection. You may resume normal activities immediately.
Timeline: Reports are typically available within 3 to 4 weeks from the date the sample is received at the laboratory.
Patient Instructions
About This Test
Who Should Get This Test
To identify pathogenic mutations in the ARHGEF10 gene associated with autosomal dominant slowed nerve conduction velocity, aiding in diagnosis, prognosis, and genetic counseling.
How to Prepare
- Collect blood in an EDTA vacutainer; mix gently by inverting.
- For FTA card, place one drop of blood on the marked circle and allow to dry at room temperature.
- Label the sample container with patient name, date of birth, and collection date.
- Ensure the sample is shipped to the laboratory within 24-48 hours if transported at ambient temperature.
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"This genetic test helps identify the underlying genetic cause of slowed nerve conduction velocity, enabling accurate diagnosis and family counseling."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed or clotted blood sample
- Insufficient sample volume
- Mislabelled or unlabeled sample
- Sample leaked during transport
Understanding Your Results
Positive for a pathogenic/likely pathogenic variant
Confirms genetic cause; autosomal dominant inheritance; consult neurologist and genetic counselor.
Negative (no pathogenic variant detected)
Does not rule out a genetic cause; other genes or mechanisms may be involved.
Variant of Uncertain Significance (VUS)
A variant was found but its clinical significance is unknown; further family studies may be needed.
Consult a neurologist or clinical geneticist if you experience persistent neurological symptoms or if you are considering genetic testing for hereditary neuropathy.
Limitations
- ⚠Test detects mutations in coding regions and splice sites; mutations in regulatory regions may be missed.
- ⚠Large deletions, duplications, or structural variants may not be detected by standard NGS panels.
- ⚠False negative results may occur if the mutation is low-level mosaic or not covered by the assay.
Risks & Considerations
- ●Minor bruising or discomfort at the blood draw site
- ●Fainting or dizziness during or after collection
Interfering Factors
- ●Maternal cell contamination in sample
- ●Degraded DNA due to improper storage
- ●Prior allogeneic hematopoietic stem cell transplant
Compare With Similar Tests
| Test | ARHGEF10 Gene Slowed nerve conduction velocity, autosomanal dominant NGS Genetic Test | Peripheral Neuropathy NGS Panel | Charcot-Marie-Tooth (CMT) Genetic Panel |
|---|---|---|---|
| Comparison | ARHGEF10 Gene Slowed nerve conduction velocity, autosomanal dominant NGS Genetic Test |
Frequently Asked Questions
What is the ARHGEF10 gene?
What is slowed nerve conduction velocity?
What does autosomal dominant inheritance mean?
Who should consider this ARHGEF10 gene NGS test?
What is the cost of the ARHGEF10 gene NGS test in India?
How is the ARHGEF10 gene NGS test performed?
What sample type is required for this test?
Is fasting required before the ARHGEF10 gene test?
How long will it take to get the test results?
What does a positive result mean?
What does a negative result mean?
Are there any risks associated with this test?
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We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
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