Skip to main content
DNA Labs India

ATP1A2 Gene Familial hemiplegic migraine type 2 NGS Genetic Test

DNA Labs India | ISO 9001:2015 Certified

ATP1A2 Gene Familial hemiplegic migraine type 2 NGS Genetic Test

Short Name: ATP1A2 FHM2 NGS Genetic Test

Also known as: FHM2 Genetic Test, ATP1A2 Mutation Analysis, Hemiplegic Migraine Gene Test

ATP1A2 Gene Familial hemiplegic migraine type 2 NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses NGS Technology on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 Weeks. Free home collection in 300+ cities across India.

NGS Genetic Test🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr SULOCHANA HEMCHANDRA HOLLA

Dr SULOCHANA HEMCHANDRA HOLLA

Consultant Medical Geneticist · Reg: 8532

Last reviewed: September 7, 2026

Overview

The purpose of this test is to detect mutations in the ATP1A2 gene to confirm a diagnosis of Familial Hemiplegic Migraine Type 2, aid in differential diagnosis from other types of migraines or neurological disorders, provide information for genetic counseling, and guide treatment decisions.

Test Code
1618
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
3 to 4 Weeks
Fasting Required
No
Method
NGS Technology
Step 1

Sample Collection

Patient should provide clinical history and undergo genetic counseling. No specific preparation is required.

Method: Venipuncture

Step 2

Laboratory Analysis

A blood sample is collected via venipuncture or a saliva sample is provided.

Step 3

Report Delivery

Sample is sent to the laboratory for analysis. Results are available in 3-4 weeks.

Timeline: 3 to 4 Weeks

Patient Instructions

1
Before the Test:Genetic counseling to discuss implications and family history.
2
During the Test:Sample collection and submission to laboratory.
3
After the Test:Wait for results and schedule follow-up with doctor.

About This Test

Who Should Get This Test

The purpose of this test is to detect mutations in the ATP1A2 gene to confirm a diagnosis of Familial Hemiplegic Migraine Type 2, aid in differential diagnosis from other types of migraines or neurological disorders, provide information for genetic counseling, and guide treatment decisions.

How to Prepare

  • Fast for 8-12 hours if required, but typically not needed for genetic tests
  • Bring valid ID and prescription
  • Wear comfortable clothing for blood draw

Doctor's Notes

Reviewed by — MBBS, MD (Medical Genetics) · Reg. No. 8532

"Genetic testing for FHM2 is essential for accurate diagnosis and helps in family planning and management of symptoms."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card
Sample Volume5 ml
ContainerEDTA tube
Collection MethodVenipuncture

Sample Stability

Blood samples should be stored at 2-8°C and transported within 24 hours
Extracted DNA can be stored at -20°C for longer periods
Sample Rejection Criteria:
  • Hemolyzed or clotted blood samples
  • Insufficient sample volume
  • Contaminated samples

Understanding Your Results

Results indicate the presence or absence of mutations in the ATP1A2 gene. A positive result confirms genetic predisposition to FHM2, while a negative result does not entirely rule out the condition due to possible other genetic factors.
📊

Positive for pathogenic variant

Confirms diagnosis of FHM2. Genetic counseling recommended.

📊

Negative

No mutations detected. Clinical correlation advised.

📊

Variant of uncertain significance

Further testing or family studies may be needed.

⚠️ When to Consult a Doctor:

If you experience recurrent headaches with temporary paralysis, numbness, or other neurological symptoms, consult a neurologist or geneticist for evaluation.

Limitations

  • ⚠May not detect all types of mutations
  • ⚠Results require interpretation by a geneticist
  • ⚠Does not rule out other genetic causes of migraine

Risks & Considerations

  • ●Minimal physical risk from blood draw
  • ●Psychological impact of genetic results
  • ●Risk of misinterpretation without counseling

Interfering Factors

  • ●Sample contamination
  • ●DNA degradation
  • ●Technical errors in sequencing

Compare With Similar Tests

TestATP1A2 Gene Familial hemiplegic migraine type 2 NGS Genetic TestCACNA1A Gene Test for FHM1Migraine Panel
ComparisonATP1A2 Gene Familial hemiplegic migraine type 2 NGS Genetic Test

Frequently Asked Questions

What is Familial Hemiplegic Migraine Type 2 (FHM2)?
FHM2 is a rare genetic disorder characterized by severe migraines with temporary paralysis on one side of the body, caused by mutations in the ATP1A2 gene.
What causes FHM2?
FHM2 is caused by mutations in the ATP1A2 gene, which affects brain cell function and is inherited in an autosomal dominant pattern.
What are the symptoms of FHM2?
Symptoms include hemiplegic attacks, aura with visual disturbances, numbness, speech difficulties, nausea, and sensitivity to light and sound.
How is FHM2 diagnosed?
Diagnosis involves clinical evaluation, family history, and genetic testing such as the ATP1A2 Gene NGS Test to identify mutations.
What is the ATP1A2 Gene NGS Genetic Test?
It is a Next-Generation Sequencing test that analyzes DNA to detect mutations in the ATP1A2 gene for confirming FHM2 diagnosis.
How is the test performed?
The test uses a blood or saliva sample collected non-invasively, which is analyzed using NGS technology in a laboratory.
What is the cost of the test in India?
The cost is approximately INR 20,000, with possible variations by facility. Home collection is available in many cities.
Is the test painful?
The test involves a simple blood draw or saliva collection, causing minimal discomfort similar to a routine blood test.
How long does it take to get results?
Results are typically available within 3 to 4 weeks after sample collection.
Can the test be done at home?
Yes, DNA Labs India offers free home sample collection for online bookings in various cities across India.
Is genetic counseling required before the test?
Yes, genetic counseling is recommended to discuss test implications, family history, and result interpretation.
What if the test result is positive?
A positive result confirms FHM2 diagnosis, enabling appropriate treatment, management, and family counseling. Consult a healthcare provider for next steps.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

Related Tests

Angelman Syndrome Test

₹10,000

Duchenne / Becker Muscular Dystrophy (DMD / BMD) Gene Mutation Test

₹14,000

Episodic Ataxia Type 1 Hotspot Test

₹11,500

Episodic Ataxia Comprehensive Profile Hotspot Test

₹16,000

Megalencephalic Leukoencephalopathy with Subcortical Cysts Van Der Knaap and Nalband MLC Gene Hotspot Mutation Test

₹7,500

Analyzer 18 SMA 18 Test Panel

₹1,755
For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

Book Your Test

Enter your details and we'll connect you within 15 minutes.

🧬

Quick Connect

Enter your mobile number and we’ll connect you with the team.

+91

✅ Connecting you now...

🔒 Your number is used to respond to this request.