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ATP1A3 Gene Alternating Hemiplegia of Childhood Type 2 NGS Genetic Test

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ATP1A3 Gene Alternating Hemiplegia of Childhood Type 2 NGS Genetic Test

Short Name: ATP1A3 NGS AHC Type 2 Test

Also known as: ATP1A3 Gene Mutation Analysis, AHC Type 2 Genetic Test, Alternating Hemiplegia of Childhood Type 2 NGS Test

ATP1A3 Gene Alternating Hemiplegia of Childhood Type 2 NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in Reports are delivered within 3 to 4 weeks after the sample is received by the laboratory.. Free home collection in 300+ cities across India.

NGS Genetic TestPediatric🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr SHAILAJA RAGHUNATH MURDESHWAR

Dr SHAILAJA RAGHUNATH MURDESHWAR

Consultant Physician · Reg: 8052

Last reviewed: September 7, 2026

Overview

The purpose of this test is to identify pathogenic variants in the ATP1A3 gene that cause alternating hemiplegia of childhood type 2. It supports diagnosis, prognosis, and genetic counseling for affected families.

Test Code
3864
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
Reports are delivered within 3 to 4 weeks after the sample is received by the laboratory.
Fasting Required
No
Method
Next Generation Sequencing (NGS)
Step 1

Sample Collection

No special preparation is needed. Please provide the patient's clinical history and family pedigree. A genetic counseling session is advised before testing.

Method: Venipuncture or FTA card spot

Step 2

Laboratory Analysis

A blood sample is collected from a vein. For FTA card, one drop of blood is applied to the designated card.

Step 3

Report Delivery

No specific aftercare is required. The patient can resume normal activities immediately.

Timeline: Reports are delivered within 3 to 4 weeks after the sample is received by the laboratory.

Patient Instructions

1
Before the Test:No fasting is required. Bring medical records and any previous genetic test results if available.
2
During the Test:A simple blood draw or FTA card blood spot will be taken. The procedure is quick and usually painless.
3
After the Test:You can return to normal activities. The report will be shared online within 3-4 weeks.

About This Test

Who Should Get This Test

The purpose of this test is to identify pathogenic variants in the ATP1A3 gene that cause alternating hemiplegia of childhood type 2. It supports diagnosis, prognosis, and genetic counseling for affected families.

How to Prepare

  • Blood sample should be collected in an EDTA vacutainer
  • FTA card should be labeled with patient details
  • Ensure proper labeling of the sample

Doctor's Notes

Reviewed by — MBBS, MD (General Medicine) · Reg. No. 8052

"Pediatric neurological expertise is vital for diagnosing AHC and guiding treatment. We provide comprehensive support for families undergoing genetic testing."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card
Sample VolumeOne drop (FTA card) or 2 mL blood
ContainerEDTA tube or FTA Card
Collection MethodVenipuncture or FTA card spot

Sample Stability

Blood: 24 hours at room temperature
FTA card: stable for several months at room temperature
Extracted DNA: stable for years at -20°C
Sample Rejection Criteria:
  • Clotted blood sample
  • Hemolyzed sample
  • Insufficient sample quantity
  • Improperly labeled sample

Understanding Your Results

The ATP1A3 gene NGS test identifies pathogenic variants associated with AHC type 2. A positive result confirms the clinical diagnosis.
Positive: Pathogenic variant detected, confirming diagnosis of AHC type 2
Negative: No pathogenic variant identified; alternative causes should be considered
Variant of Uncertain Significance (VUS): Further testing and family segregation analysis may be recommended
⚠️ When to Consult a Doctor:

Consult a pediatric neurologist or geneticist if your child shows symptoms of alternating hemiplegia or unexplained paroxysmal neurological events.

Limitations

  • ⚠NGS may not detect large deletions or duplications within the ATP1A3 gene
  • ⚠Variants of unknown significance may be reported, requiring further family studies
  • ⚠This test cannot exclude non-ATP1A3 causes of AHC

Risks & Considerations

  • ●Minimal bleeding at the needle site
  • ●Mild soreness or bruising at the collection site
  • ●No significant serious risks associated with blood collection

Interfering Factors

  • ●Maternal cell contamination
  • ●DNA contamination during sample handling
  • ●Recent allogeneic bone marrow transplant

Compare With Similar Tests

TestATP1A3 Gene Alternating Hemiplegia of Childhood Type 2 NGS Genetic Test
ComparisonATP1A3 Gene Alternating Hemiplegia of Childhood Type 2 NGS Genetic Test

Frequently Asked Questions

What is the ATP1A3 gene Alternating Hemiplegia of Childhood Type 2 NGS genetic test?
It is a next-generation sequencing test that analyzes the ATP1A3 gene to identify mutations causing AHC type 2.
What sample is needed for this test?
A blood sample in an EDTA tube, or one drop of blood on an FTA card, or extracted DNA.
Do I need to fast before the test?
No, fasting is not required for this genetic test.
How is the test performed?
DNA is extracted from the sample and sequenced using NGS technology to detect variants in the ATP1A3 gene.
What is the cost of the test?
The test costs INR 20000, which includes sample collection and analysis.
How long does it take to get the reports?
Reports are typically delivered within 3 to 4 weeks.
Is home sample collection available?
Yes, DNA Labs India offers free home sample collection for this test in many cities across India.
Can this test confirm a diagnosis of AHC?
Yes, if a pathogenic variant in ATP1A3 is found, it confirms the diagnosis of AHC type 2.
Who should undergo this genetic test?
Children with recurrent episodes of hemiplegia or other symptoms suggestive of AHC, and family members for genetic counseling.
Does insurance cover this test?
Most insurance plans do not cover this test, but coverage depends on individual policy terms.
What does a negative result mean?
A negative result means no pathogenic variant was found in the ATP1A3 gene. Clinical diagnosis may still be considered based on symptoms.
What is the difference between ATP1A3 gene and AHC type 2?
Mutations in the ATP1A3 gene cause AHC type 2, a specific genetic form of alternating hemiplegia. This test targets that gene.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

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We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

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Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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