BCR-ABL Quantitative MRD Monitor Test
Short Name: BCR-ABL Quantitative MRD Monitor
Also known as: BCR-ABL MRD Test, Minimal Residual Disease Monitor
BCR-ABL Quantitative MRD Monitor Test test available at DNA Labs India for ₹8,200. Uses Real-Time PCR on Whole Blood / Bone Marrow samples. Results in Reports are typically available within 1-2 days after sample receipt at the laboratory, delivered via online portal, email, or WhatsApp.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Pasupathy Arumugam
Consultant Pathologist · Reg: 21521
Last reviewed: September 7, 2026
Overview
To quantify BCR-ABL transcript levels for monitoring treatment response and detecting minimal residual disease in patients with Chronic Myeloid Leukemia.
- Test Code
- 196
- Price
- ₹8,200
- Sample Type
- Whole Blood / Bone Marrow
- Result Time
- Reports are typically available within 1-2 days after sample receipt at the laboratory, delivered via online portal, email, or WhatsApp.
- Fasting Required
- No
- Method
- Real-Time PCR
Sample Collection
Complete and submit the MRD Requisition Form (Form 22) with patient's historical test results and clinical information.
Method: Venipuncture
Laboratory Analysis
Collect 5 mL of whole blood or bone marrow in an EDTA tube via standard venipuncture or aspiration.
Report Delivery
Label the sample properly, refrigerate immediately, and ship to the laboratory on Mon, Wed, or Fri by 9 AM. Do not freeze.
Timeline: Reports are typically available within 1-2 days after sample receipt at the laboratory, delivered via online portal, email, or WhatsApp.
Patient Instructions
About This Test
Who Should Get This Test
To quantify BCR-ABL transcript levels for monitoring treatment response and detecting minimal residual disease in patients with Chronic Myeloid Leukemia.
How to Prepare
- Fill out MRD Requisition Form (Form 22) completely with historical data
- Collect minimum 5 mL sample in Lavender Top EDTA tube
- Refrigerate sample at 2-8°C after collection
- Ship sample on specified days (Mon, Wed, Fri) for timely processing
Doctor's Notes
Reviewed by Dr Pasupathy Arumugam — MBBS, MD (Pathology) · Reg. No. 21521
"Regular monitoring with BCR-ABL quantitative tests is essential for optimizing treatment and achieving deep molecular responses in CML patients."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed or clotted sample
- Insufficient sample volume (<3 mL)
- Missing or incomplete MRD Requisition Form
- Improper sample labeling
- Sample not refrigerated during transport
Understanding Your Results
BCR-ABL ≤0.1% IS
Deep response, continue current treatment with regular monitoring
Level: Major Molecular Response (MMR)
BCR-ABL >0.1% IS and ≤1% IS
Possible loss of response, increase monitoring frequency and consult physician
Level: Warning
BCR-ABL >1% IS
Inadequate response, consider changing therapy or investigating resistance mutations
Level: Treatment Failure
If test results show rising BCR-ABL levels, or if symptoms of CML such as fatigue, bone pain, or splenomegaly persist or worsen.
Limitations
- ⚠Cannot detect all BCR-ABL transcript variants
- ⚠Requires historical test data for accurate interpretation
- ⚠Not suitable for initial diagnosis without clinical context
- ⚠Sensitivity limited by assay technology and sample quality
Risks & Considerations
- ●Minor pain or bruising at the needle site
- ●Rare risk of infection at puncture site
- ●No significant risks associated with the blood test itself
Interfering Factors
- ●Hemolyzed blood sample
- ●Improper sample storage or transportation
- ●Contamination with genomic DNA
- ●Recent blood transfusions or leukapheresis
Compare With Similar Tests
| Test | BCR-ABL Quantitative MRD Monitor Test | BCR-ABL Qualitative PCR | Bone Marrow Biopsy | Cytogenetic Analysis |
|---|---|---|---|---|
| Comparison | BCR-ABL Quantitative MRD Monitor Test | Detects presence or absence of BCR-ABL fusion, but does not quantify transcript levels | Invasive procedure providing cellular details, used for initial diagnosis and staging, not for routine MRD monitoring | Identifies chromosomal abnormalities like Philadelphia chromosome, but less sensitive for MRD detection |
Frequently Asked Questions
What is the BCR-ABL Quantitative MRD Monitor Test?
Why is this test important for CML management?
How is the test performed?
What is the cost of the test at DNA Labs India?
Is home sample collection available?
How often should this test be done?
What do the test results mean?
Are there any risks or side effects?
How should I prepare for the test?
What is the turnaround time for results?
Can this test detect all types of BCR-ABL mutations?
What is Minimal Residual Disease (MRD)?
Related Tests
Reference Laboratory Services
We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
Your Data Privacy
Your medical data is protected under Indian law.
✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.
Book Your Test
Enter your details and we'll connect you within 15 minutes.