Immunophenotyping by Flow Cytometry CD138 Test
Short Name: CD138 Flow Cytometry
Also known as: CD138 Immunophenotyping, Syndecan-1 Flow Cytometry
Immunophenotyping by Flow Cytometry CD138 Test test available at DNA Labs India for ₹3,500. Uses Flow Cytometry on Whole blood in EDTA and Sodium Heparin tubes or Bone marrow in Sodium Heparin tube samples. Results in Same-day report available for samples received by 9 am.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Pasupathy Arumugam
Consultant Pathologist · Reg: 21521
Last reviewed: September 7, 2026
Overview
The purpose of the CD138 Flow Cytometry test is to detect the presence and quantify CD138-positive plasma cells, aiding in the diagnosis of multiple myeloma and other plasma cell disorders. It helps in assessing disease severity, monitoring treatment response, and differentiating between benign and malignant conditions.
- Test Code
- 1065
- Price
- ₹3,500
- Sample Type
- Whole blood in EDTA and Sodium Heparin tubes or Bone marrow in Sodium Heparin tube
- Result Time
- Same-day report available for samples received by 9 am.
- Fasting Required
- No
- Method
- Flow Cytometry
Sample Collection
Provide a brief clinical history and specify time, date, and clinical details on the test request form. No fasting required.
Method: Venipuncture for blood; Bone marrow aspiration for marrow sample
Laboratory Analysis
For blood sample: venipuncture to collect into EDTA and Sodium Heparin tubes. For bone marrow: aspiration under local anesthesia.
Report Delivery
Ship immediately at 18-22°C. DO NOT REFRIGERATE OR FREEZE. Resume normal activities; monitor bone marrow site if applicable.
Timeline: Same-day report available for samples received by 9 am.
Patient Instructions
About This Test
Who Should Get This Test
The purpose of the CD138 Flow Cytometry test is to detect the presence and quantify CD138-positive plasma cells, aiding in the diagnosis of multiple myeloma and other plasma cell disorders. It helps in assessing disease severity, monitoring treatment response, and differentiating between benign and malignant conditions.
How to Prepare
- Collect 3 mL whole blood in EDTA tube and 3 mL in Sodium Heparin tube, or 2 mL bone marrow in Sodium Heparin tube.
- Label samples correctly with patient details.
- Maintain room temperature during transport.
Doctor's Notes
Reviewed by Dr Pasupathy Arumugam — MBBS, MD (Pathology) · Reg. No. 21521
"The CD138 Flow Cytometry test is essential for diagnosing and monitoring multiple myeloma, helping to guide personalized treatment strategies and improve patient outcomes."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Incorrect sample type or container
- Hemolyzed or lipemic samples
- Insufficient volume
- Missing clinical details
Understanding Your Results
Possible multiple myeloma, plasma cell leukemia, or other neoplastic conditions; further evaluation recommended.
Range: High CD138 expression (>5%)
No significant abnormality detected; correlate with clinical symptoms.
Range: Normal CD138 expression (1-5%)
May indicate other conditions; clinical context required.
Range: Low or absent expression
If test results are abnormal or if symptoms such as bone pain, fatigue, or infections persist, consult an oncologist or hematologist immediately for further diagnosis and management.
Limitations
- ⚠Cannot solely distinguish between reactive and neoplastic conditions without clinical correlation
- ⚠Requires specialized equipment and trained personnel
- ⚠Results may vary based on laboratory protocols
Risks & Considerations
- ●Minimal risk for blood draw: bruising or infection at puncture site
- ●Bone marrow aspiration may cause temporary pain or bleeding; rare infection risk
Interfering Factors
- ●Hemolyzed or clotted samples
- ●Improper sample storage or transport
- ●Contamination with other cells
Compare With Similar Tests
| Test | Immunophenotyping by Flow Cytometry CD138 Test | Bone Marrow Biopsy | Serum Protein Electrophoresis |
|---|---|---|---|
| Comparison | Immunophenotyping by Flow Cytometry CD138 Test | More invasive but provides detailed histological analysis of bone marrow architecture. | Detects monoclonal proteins in blood but does not specifically identify plasma cell markers like CD138. |
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