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Beta-2-Microglobulin 24 Hour Urine Test

DNA Labs India | ISO 9001:2015 Certified

Beta-2-Microglobulin 24 Hour Urine Test

Short Name: Beta-2-Microglobulin Urine Test

Also known as: B2M 24Hr Urine Test, Beta-2-Microglobulin Urine Analysis

Beta-2-Microglobulin 24 Hour Urine Test test available at DNA Labs India for ₹1,521. Uses CLIA on Urine samples. Results in Daily reports available after sample receipt.. Free home collection in 300+ cities across India.

Laboratory TestAdults🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr Pasupathy Arumugam

Dr Pasupathy Arumugam

Consultant Pathologist · Reg: 21521

Last reviewed: September 7, 2026

Overview

To detect and monitor elevated levels of beta-2-microglobulin in urine, aiding in the diagnosis of kidney damage, multiple myeloma, lymphoma, autoimmune diseases, and chronic infections.

Test Code
194
Price
₹1,521
Sample Type
Urine
Result Time
Daily reports available after sample receipt.
Fasting Required
No
Method
CLIA
Step 1

Sample Collection

No special preparation required. Inform your doctor about any medications or supplements you are taking.

Method: 24-hour urine collection

Step 2

Laboratory Analysis

Collect all urine over 24 hours in a sterile container. Record the total volume on the container and test request form.

Step 3

Report Delivery

Store the sample refrigerated or frozen. Ship to the laboratory as per instructions.

Timeline: Daily reports available after sample receipt.

Patient Instructions

1
Before the Test:No fasting or special preparation needed. Provide a 24-hour urine sample as instructed.
2
During the Test:The test involves laboratory analysis of the collected urine sample using CLIA method.
3
After the Test:Results are available daily. Access via online portal, email, or WhatsApp.

About This Test

Who Should Get This Test

To detect and monitor elevated levels of beta-2-microglobulin in urine, aiding in the diagnosis of kidney damage, multiple myeloma, lymphoma, autoimmune diseases, and chronic infections.

How to Prepare

  • Start collection after discarding the first morning urine
  • Collect all subsequent urine for 24 hours
  • Store in a sterile screw capped container
  • Do not use preservatives
  • Record 24-hour volume on the container and form
  • Ship refrigerated or frozen

Doctor's Notes

Reviewed by — MBBS, MD (Pathology) · Reg. No. 21521

"Elevated urinary beta-2-microglobulin is a key marker for renal impairment in multiple myeloma and other plasma cell dyscrasias. This test is essential for early detection and management."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeUrine
Sample Volume10 mL (5 mL min.) aliquot of 24-hour urine
ContainerSterile screw capped container
Collection Method24-hour urine collection

Sample Stability

Room Temperature: Not Applicable
Refrigerator: 24 hours
Frozen: 2 weeks
Sample Rejection Criteria:
  • Improper collection or container
  • Use of preservatives
  • Incorrect labeling
  • Sample not stored properly

Understanding Your Results

Results indicate the level of beta-2-microglobulin in urine. Elevated levels may suggest underlying medical conditions requiring further evaluation.
Elevated beta-2-microglobulin in urine may indicate kidney damage, multiple myeloma, lymphoma, or autoimmune diseases
Consult a healthcare professional for proper diagnosis and treatment
Results should be correlated with clinical symptoms and other tests
⚠️ When to Consult a Doctor:

If you experience symptoms like swelling, fatigue, shortness of breath, or have abnormal test results, consult a doctor immediately.

Limitations

  • ⚠Elevated levels may not be specific to one condition; further tests needed for confirmation
  • ⚠Not suitable for point-of-care testing; requires laboratory analysis
  • ⚠Results may vary based on individual kidney function

Risks & Considerations

  • ●Minimal risk associated with urine collection
  • ●Possible discomfort during 24-hour collection
  • ●No significant risks from the test itself

Interfering Factors

  • ●Improper 24-hour urine collection
  • ●Use of preservatives in the container
  • ●Bacterial contamination of the sample
  • ●Recent strenuous physical activity
  • ●Certain medications that may affect protein levels

Frequently Asked Questions

What is the Beta-2-Microglobulin 24 Hour Urine Test?
It is a test that measures the level of beta-2-microglobulin protein in urine collected over 24 hours to help diagnose conditions like kidney damage and multiple myeloma.
Why is this test recommended?
It is recommended when there is suspicion of kidney dysfunction, certain cancers (e.g., multiple myeloma), autoimmune diseases, or for monitoring known conditions.
How do I collect a 24-hour urine sample?
Start by discarding the first morning urine, then collect all urine in a sterile container for 24 hours, record the total volume, and store refrigerated or frozen.
What is the normal range for beta-2-microglobulin in urine?
The normal range is typically less than 0.3 mg/L, but it may vary by laboratory. Always refer to the reference range provided in your report.
What do elevated levels indicate?
Elevated levels may indicate kidney damage, multiple myeloma, lymphoma, autoimmune diseases, or chronic infections. Further tests are needed for diagnosis.
Are there any risks associated with this test?
The test itself has minimal risks, primarily related to urine collection, such as discomfort during the 24-hour period. No significant medical risks.
How long does it take to get the results?
Results are typically available daily after the sample is received at the laboratory.
Is home sample collection available?
Yes, DNA Labs India offers free home sample collection for this test across many cities in India.
What is the cost of the test?
The cost is INR 1521, which includes home collection and report delivery.
Is the test covered by insurance?
Generally, this test is not covered under most health insurance plans in India. Check with your insurance provider for details.
Can this test diagnose multiple myeloma?
It can help in diagnosing and monitoring multiple myeloma by detecting elevated beta-2-microglobulin, but a definitive diagnosis requires additional tests like biopsy and imaging.
What other tests are needed for a complete diagnosis?
Related tests may include serum beta-2-microglobulin, kidney function tests, serum protein electrophoresis, and complete blood count for comprehensive evaluation.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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