Skip to main content
DNA Labs India

C-Peptide Stimulation by Glucagon Test

DNA Labs India | ISO 9001:2015 Certified

C-Peptide Stimulation by Glucagon Test

Also known as: Glucagon Stimulation C-Peptide Test, C-Peptide Glucagon Stimulation Test

C-Peptide Stimulation by Glucagon Test test available at DNA Labs India for ₹5,500. Uses Chemiluminescent Immunoassay on Serum samples. Results in Results are typically available within 24-48 hours after sample collection.. Free home collection in 300+ cities across India.

Hormonal Stimulation TestAdults🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr SHAILAJA RAGHUNATH MURDESHWAR

Dr SHAILAJA RAGHUNATH MURDESHWAR

Consultant Physician · Reg: 8052

Last reviewed: September 7, 2026

Overview

To evaluate pancreatic beta-cell function and insulin production capacity, aiding in the diagnosis and management of diabetes mellitus.

Test Code
366
Price
₹5,500
Sample Type
Serum
Result Time
Results are typically available within 24-48 hours after sample collection.
Fasting Required
Yes (12 hours)
Method
Chemiluminescent Immunoassay
Step 1

Sample Collection

12 hours overnight fasting mandatory. Avoid strenuous exercise prior to test. Inform your doctor about any medications.

Method: Venipuncture

Step 2

Laboratory Analysis

A baseline blood sample will be drawn, followed by an intravenous injection of glucagon. Additional samples will be taken at 5, 10, and 15 minutes post-injection.

Step 3

Report Delivery

Apply pressure to the puncture site to prevent bruising. Resume normal activities as advised by your healthcare provider.

Timeline: Results are typically available within 24-48 hours after sample collection.

Patient Instructions

1
Before the Test:Ensure you have fasted for 12 hours. Inform the healthcare provider of any allergies, medications, or medical conditions.
2
During the Test:The test involves a blood draw, glucagon injection, and subsequent blood draws. You may feel a slight sting from the needle and possibly nausea from the glucagon.
3
After the Test:You may resume normal eating and activities. Some people may experience temporary nausea from the glucagon injection, which typically resolves quickly.

About This Test

Who Should Get This Test

To evaluate pancreatic beta-cell function and insulin production capacity, aiding in the diagnosis and management of diabetes mellitus.

How to Prepare

  • Fast for 12 hours before the test
  • Inform your doctor about any allergies or medical conditions
  • Wear comfortable clothing for easy blood draw

Doctor's Notes

Reviewed by — MBBS, MD (General Medicine) · Reg. No. 8052

"The C-Peptide Stimulation by Glucagon Test is essential for evaluating beta-cell reserve in patients with diabetes, helping to tailor treatment plans effectively."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeSerum
Sample Volume2 mL (0.5 mL min.)
ContainerSerum Separator Tube (SST)
Collection MethodVenipuncture

Sample Stability

Room Temperature: 8 hours
Refrigerated: 24 hours
Frozen: 2 weeks
Sample Rejection Criteria:
  • Hemolyzed or lipemic samples
  • Incorrect sample volume
  • Missing patient information or labels

Understanding Your Results

Results of the C-Peptide Stimulation test indicate the capacity of the pancreas to produce insulin in response to glucagon stimulation.
Normal response: C-peptide levels increase significantly after glucagon injection, indicating adequate beta-cell function.
Low response: May suggest type 1 diabetes or pancreatic damage.
High response: Could indicate insulin resistance or type 2 diabetes.
⚠️ When to Consult a Doctor:

If you experience symptoms such as excessive thirst, frequent urination, unexplained weight loss, or persistent fatigue, consult your doctor for evaluation.

Limitations

  • ⚠Does not directly measure insulin levels
  • ⚠May be affected by renal impairment
  • ⚠Glucagon injection can cause nausea in some patients

Risks & Considerations

  • ●Minor bruising or discomfort at the puncture site
  • ●Nausea or vomiting from glucagon injection
  • ●Rare allergic reaction to glucagon

Interfering Factors

  • ●Recent insulin use
  • ●Presence of insulin antibodies
  • ●Kidney or liver disease
  • ●Certain medications affecting insulin secretion

Compare With Similar Tests

TestC-Peptide Stimulation by Glucagon TestFasting Insulin TestHbA1c Test
ComparisonC-Peptide Stimulation by Glucagon Test

Frequently Asked Questions

What is the purpose of a C-peptide stimulation by glucagon test?
This test evaluates how well your pancreas produces insulin by measuring C-peptide levels after glucagon stimulation, helping diagnose and manage diabetes.
How should I prepare for the test?
You must fast for 12 hours overnight before the test. Avoid strenuous exercise and inform your doctor about any medications.
What are the normal ranges for C-peptide levels?
Normal ranges vary by laboratory; generally, baseline fasting C-peptide is 0.5-2.0 ng/mL, with a significant increase post-glucagon.
How long does the test take?
The test procedure takes about 30-45 minutes, including baseline sampling and post-glucagon blood draws at 5, 10, and 15 minutes.
Are there any side effects of the glucagon injection?
Common side effects include nausea, vomiting, or headache, which usually resolve quickly. Rarely, allergic reactions may occur.
What does a low C-peptide level indicate?
A low C-peptide level after stimulation may suggest insufficient insulin production, commonly seen in type 1 diabetes or pancreatic damage.
Can this test diagnose type 1 diabetes?
Yes, it helps differentiate between type 1 and type 2 diabetes by assessing pancreatic beta-cell function.
Is the test painful?
You may feel a slight needle prick during blood draws and injection, but it is generally well-tolerated.
How accurate is the C-peptide stimulation test?
When performed correctly, it is a reliable indicator of insulin production, but results should be interpreted alongside clinical symptoms and other tests.
What if I forget to fast before the test?
Fasting is mandatory; if you forget, inform the healthcare provider, as the test may need to be rescheduled for accurate results.
How soon will I get my results?
Results are typically available within 24-48 hours after sample collection, accessible via online portal, email, or WhatsApp.
Is home collection available for this test?
Yes, DNA Labs India offers free home sample collection for this test in many cities across India for your convenience.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

Related Tests

17-Hydroxypregnenolone Test

₹15,000

Congenital Hypothyroidism Confirmatory Panel Serum Test

₹900

17-Hydroxy-Corticosteroids & 17-Ketosteroids 24 Hour Urine Test

₹17,500

17-Hydroxyprogesterone (17-OHP) Test

₹1,521

5?-Dihydrotestosterone (5?-DHT) Test

₹4,000

Androgen Index Test

₹4,000
For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

Book Your Test

Enter your details and we'll connect you within 15 minutes.

🧬

Quick Connect

Enter your mobile number and we’ll connect you with the team.

+91

✅ Connecting you now...

🔒 Your number is used to respond to this request.