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C1 Esterase Inhibitor Protein Quantitation (C1 Inhibitor Quantitative) Test

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C1 Esterase Inhibitor Protein Quantitation (C1 Inhibitor Quantitative) Test

Short Name: C1 INH Quantitative Test

Also known as: C1 INH Quantitative Test, C1 Esterase Inhibitor Test

C1 Esterase Inhibitor Protein Quantitation (C1 Inhibitor Quantitative) Test test available at DNA Labs India for ₹2,574. Uses Radial Immunodiffusion on Serum samples. Results in Reports are typically available within 4-5 days after sample collection, as indicated for Wednesday samples by 9 am with reports by next Monday.. Free home collection in 300+ cities across India.

Quantitative Immunoassay🏠 Home Collection

Overview

To measure the level of C1 Esterase Inhibitor protein in the blood for the diagnosis and monitoring of Hereditary Angioedema.

Test Code
233
Price
₹2,574
Sample Type
Serum
Result Time
Reports are typically available within 4-5 days after sample collection, as indicated for Wednesday samples by 9 am with reports by next Monday.
Fasting Required
Yes
Method
Radial Immunodiffusion
Step 1

Sample Collection

Overnight fasting is preferred. Inform your doctor about any medications, supplements, or medical conditions.

Method: Venipuncture

Step 2

Laboratory Analysis

A blood sample will be drawn from a vein in your arm using standard venipuncture technique.

Step 3

Report Delivery

Apply pressure to the puncture site to stop bleeding. Resume normal activities unless otherwise advised.

Timeline: Reports are typically available within 4-5 days after sample collection, as indicated for Wednesday samples by 9 am with reports by next Monday.

Patient Instructions

1
Before the Test:Follow overnight fasting instructions. Inform your healthcare provider about all medications and medical history.
2
During the Test:The test involves a simple blood draw from a vein, typically taking a few minutes.
3
After the Test:You can resume normal activities immediately. Monitor the puncture site for any signs of bruising or infection.

About This Test

Who Should Get This Test

To measure the level of C1 Esterase Inhibitor protein in the blood for the diagnosis and monitoring of Hereditary Angioedema.

How to Prepare

  • Do not use SST gel barrier tubes.
  • Separate serum within 1 hour of collection.
  • Ship refrigerated or frozen as per stability guidelines.

Doctor's Notes

"This test is essential for diagnosing Hereditary Angioedema, a potentially life-threatening condition. Early detection enables effective management and prevention of severe swelling episodes."

Test Parameters & Specifications

Sample TypeSerum
Sample Volume2 mL (0.5 mL min.)
ContainerRed Top (No Additive) tube
Collection MethodVenipuncture

Sample Stability

Room Temperature
Refrigerator
Frozen
Sample Rejection Criteria:
  • Hemolyzed samples
  • Improperly labeled or unlabeled samples
  • Insufficient sample volume
  • Use of incorrect collection tube (e.g., SST gel barrier tubes)

Understanding Your Results

The C1 Esterase Inhibitor protein level is crucial for diagnosing Hereditary Angioedema. Low levels typically indicate HAE type I, while dysfunctional protein may suggest type II.
📊

Low C1 INH level

Suggestive of Hereditary Angioedema type I. Further testing recommended for confirmation.

📊

Normal or high C1 INH level with dysfunction

May indicate Hereditary Angioedema type II. Functional assay is advised.

📊

Normal C1 INH level

Less likely to be HAE, but consider other causes of angioedema or repeat testing if symptoms persist.

⚠️ When to Consult a Doctor:

If you experience recurrent swelling, difficulty breathing, severe abdominal pain, or have a family history of HAE, consult a doctor immediately for evaluation.

Limitations

  • May not detect all subtypes of Hereditary Angioedema
  • Should be interpreted in conjunction with clinical symptoms and other diagnostic tests
  • Results can be affected by acute phase reactions

Risks & Considerations

  • Minor bruising or discomfort at the blood draw site
  • Slight risk of infection
  • Rare cases of dizziness or fainting

Interfering Factors

  • Hemolyzed samples
  • Improper sample handling or delayed separation
  • Recent blood transfusion
  • Certain medications (e.g., antifibrinolytics, estrogen therapy)

Compare With Similar Tests

TestC1 Esterase Inhibitor Protein Quantitation (C1 Inhibitor Quantitative) TestC4 Complement TestC1 INH Functional AssayGenetic Testing for HAEComplete Blood Count (CBC)
ComparisonC1 Esterase Inhibitor Protein Quantitation (C1 Inhibitor Quantitative) Test

Frequently Asked Questions

What is the C1 Esterase Inhibitor Protein Quantitation Test?
It is a blood test that measures the level of C1 Esterase Inhibitor protein to help diagnose Hereditary Angioedema (HAE).
Why is this test performed?
To diagnose and monitor Hereditary Angioedema, a genetic disorder causing recurrent swelling episodes.
How is the test conducted?
A blood sample is drawn from a vein, and the serum is analyzed using radial immunodiffusion to quantify the protein.
What are the symptoms of Hereditary Angioedema?
Symptoms include swelling of the face, lips, tongue, throat, genitals, abdominal pain, nausea, vomiting, difficulty breathing, and fatigue.
What is the cost of the test in India?
The cost is approximately INR 2574, with possible variations based on location and laboratory.
Is fasting required for this test?
Yes, overnight fasting is preferred to ensure accurate results.
How long does it take to get the results?
Results are typically available within 4-5 days after sample collection.
Is home sample collection available?
Yes, DNA Labs India offers free home collection in many cities across India.
What if the test results are abnormal?
Abnormal results may indicate Hereditary Angioedema; consult your doctor for further evaluation and management.
Can this test diagnose all types of HAE?
It helps identify type I and II HAE, but additional tests like functional assays or genetic testing may be needed for confirmation.
Is the test covered by insurance?
It is covered by some insurance plans; check with your provider for specific coverage details.
How accurate is the C1 INH Quantitative Test?
The test is reliable when performed correctly, but results should be interpreted alongside clinical symptoms and other diagnostic tests.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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