C3 Gene C3 deficiency NGS Genetic Test
Short Name: C3 Deficiency NGS Test
Also known as: Complement C3 Genetic Test, C3 Gene Mutation Analysis, C3 Deficiency Screening
C3 Gene C3 deficiency NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 Weeks. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
To diagnose C3 deficiency by identifying mutations in the C3 gene using NGS technology, aiding in the management of recurrent infections and immune system dysfunction.
- Test Code
- 4865
- Price
- ₹20,000
- Sample Type
- Blood or Extracted DNA or One drop Blood on FTA Card
- Result Time
- 3 to 4 Weeks
- Fasting Required
- No
- Method
- Next-Generation Sequencing (NGS)
Sample Collection
No specific preparation required. Provide clinical history and genetic counseling if needed.
Method: Venipuncture
Laboratory Analysis
Blood sample collected via venipuncture by a trained phlebotomist.
Report Delivery
Apply pressure to the puncture site to prevent bruising. Resume normal activities.
Timeline: 3 to 4 Weeks
Patient Instructions
About This Test
Who Should Get This Test
To diagnose C3 deficiency by identifying mutations in the C3 gene using NGS technology, aiding in the management of recurrent infections and immune system dysfunction.
How to Prepare
- Ensure proper identification of patient
- Use sterile equipment for blood draw
- Label samples correctly
- Transport samples at ambient temperature
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"Genetic testing for C3 deficiency is essential for early diagnosis and management of recurrent infections, especially in patients with a family history or unexplained immunodeficiency symptoms."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed or clotted samples
- Incorrect labeling
- Insufficient sample volume
Understanding Your Results
Negative
No pathogenic variants detected; C3 deficiency unlikely based on genetic analysis.
Positive
Pathogenic variant(s) identified; confirms C3 deficiency diagnosis. Clinical correlation and further testing advised.
Variant of Uncertain Significance (VUS)
Genetic change detected but significance unclear; may require family studies or follow-up.
Consult a doctor if you have recurrent infections, a family history of C3 deficiency, or if test results are positive or uncertain for guidance on management and treatment.
Limitations
- ⚠May not detect all rare variants or deep intronic mutations
- ⚠Results require clinical correlation
- ⚠Not suitable for carrier testing without family history
Risks & Considerations
- ●Minor bruising or discomfort at blood draw site
- ●Rare risk of infection or fainting
Interfering Factors
- ●Sample contamination
- ●Degraded DNA
- ●Incorrect sample storage
Frequently Asked Questions
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Reference Laboratory Services
We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
Your Data Privacy
Your medical data is protected under Indian law.
✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.
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