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CACNA1A Gene Familial hemiplegic migraine type 1 NGS Genetic Test

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CACNA1A Gene Familial hemiplegic migraine type 1 NGS Genetic Test

Short Name: CACNA1A Gene FHM1 NGS Test

Also known as: Familial Hemiplegic Migraine Type 1 Genetic Test, CACNA1A Mutation Analysis

CACNA1A Gene Familial hemiplegic migraine type 1 NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood or Extracted DNA samples. Results in 3-4 weeks. Free home collection in 300+ cities across India.

NGS Genetic Test🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr SULOCHANA HEMCHANDRA HOLLA

Dr SULOCHANA HEMCHANDRA HOLLA

Consultant Medical Geneticist · Reg: 8532

Last reviewed: September 7, 2026

Overview

To identify mutations in the CACNA1A gene for diagnosis of Familial Hemiplegic Migraine Type 1.

Test Code
1615
Price
₹20,000
Sample Type
Blood or Extracted DNA
Result Time
3-4 weeks
Fasting Required
No
Method
Next-Generation Sequencing (NGS)
Step 1

Sample Collection

No specific preparation required, but genetic counseling recommended.

Method: Venipuncture or FTA card collection

Step 2

Laboratory Analysis

Blood sample collected via venipuncture or on FTA card.

Step 3

Report Delivery

Apply pressure to puncture site; store sample properly.

Timeline: 3-4 weeks

Patient Instructions

1
Before the Test:Consult with a genetic counselor to discuss implications.
2
During the Test:Blood draw or sample collection as per instructions.
3
After the Test:Wait for 3-4 weeks for results; genetic counseling recommended post-test.

About This Test

Who Should Get This Test

To identify mutations in the CACNA1A gene for diagnosis of Familial Hemiplegic Migraine Type 1.

How to Prepare

  • Use sterile equipment
  • Label samples correctly
  • Follow home collection guidelines if applicable

Doctor's Notes

Reviewed by — MBBS, MD (Medical Genetics) · Reg. No. 8532

"Genetic testing for CACNA1A mutations is crucial for diagnosing familial hemiplegic migraine, especially in families with a history of neurological disorders."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA
Sample VolumeStandard blood volume
ContainerEDTA tube or FTA card
Collection MethodVenipuncture or FTA card collection

Sample Stability

Blood: 7 days at 2-8°C
FTA card: Room temperature for extended periods
Sample Rejection Criteria:
  • Hemolyzed or clotted samples
  • Insufficient volume
  • Unlabeled samples

Understanding Your Results

Genetic test results for CACNA1A mutations indicate the presence or absence of pathogenic variants associated with Familial Hemiplegic Migraine Type 1.
📊

Positive for pathogenic variant

Confirms diagnosis of FHM1; genetic counseling advised.

📊

Negative

No mutation detected; clinical correlation recommended.

📊

Variant of uncertain significance

Further testing or family studies may be needed.

⚠️ When to Consult a Doctor:

If symptoms of hemiplegic migraine occur, or for family members of affected individuals.

Limitations

  • ⚠May not detect all types of mutations (e.g., large deletions)
  • ⚠Results require genetic counseling for interpretation

Risks & Considerations

  • ●Bruising
  • ●Infection (rare)
  • ●Fainting

Interfering Factors

  • ●DNA degradation
  • ●Sample contamination
  • ●Hemolyzed blood sample

Compare With Similar Tests

TestCACNA1A Gene Familial hemiplegic migraine type 1 NGS Genetic Test
ComparisonCACNA1A Gene Familial hemiplegic migraine type 1 NGS Genetic Test

Frequently Asked Questions

What is the CACNA1A Gene Test?
The CACNA1A Gene Test is a genetic test that analyzes the CACNA1A gene for mutations associated with Familial Hemiplegic Migraine Type 1.
Why is this test recommended for Familial Hemiplegic Migraine?
It helps confirm the diagnosis of FHM1 by identifying mutations in the CACNA1A gene, which is a common cause of this disorder.
How is the test performed?
A blood sample or extracted DNA is collected, and next-generation sequencing is used to sequence the entire CACNA1A gene.
What are the symptoms of Familial Hemiplegic Migraine Type 1?
Symptoms include severe headache, nausea, vomiting, sensitivity to light and sound, temporary paralysis on one side, and visual disturbances.
How long does it take to get the test results?
Results are typically available within 3 to 4 weeks after sample collection.
Is home sample collection available for this test?
Yes, DNA Labs India offers free home sample collection for online bookings across India.
What is the cost of the CACNA1A Gene Test?
The test costs INR 20,000 at DNA Labs India.
Can this test be used for prenatal diagnosis?
It is primarily for diagnostic purposes in affected individuals; for prenatal testing, genetic counseling is advised.
What does a positive test result mean?
A positive result indicates the presence of a pathogenic mutation in the CACNA1A gene, confirming a diagnosis of FHM1.
What are the limitations of the test?
The test may not detect all mutation types, and results require interpretation by a genetic counselor.
Is genetic counseling required before taking the test?
Genetic counseling is recommended to discuss the implications of testing and results.
How accurate is the NGS genetic test for CACNA1A?
NGS provides high sensitivity and specificity, making it a reliable method for detecting mutations.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

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We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

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