Carbamazepine Free Test
Short Name: CBZ Free Test
Also known as: Carbamazepine Sensitivity Test, CBZ IgE Test, Carbamazepine Free IgE Test
Carbamazepine Free Test test available at DNA Labs India for ₹10,000. Uses LC-MS/MS on Serum samples. Results in Results are typically available 2-3 weeks after sample collection, with the sample to be submitted by the 7th of the month.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SHAILAJA RAGHUNATH MURDESHWAR
Consultant Physician · Reg: 8052
Last reviewed: September 7, 2026
Overview
The primary purpose of the Carbamazepine Free Test is to confirm or rule out hypersensitivity to carbamazepine in individuals showing adverse symptoms during treatment. By quantifying CBZ-specific IgE antibodies, it aids in diagnosing drug-induced allergic reactions, guiding clinical decisions to discontinue or switch medications, and preventing life-threatening complications such as Stevens-Johnson syndrome or toxic epidermal necrolysis.
- Test Code
- 268
- Price
- ₹10,000
- Sample Type
- Serum
- Result Time
- Results are typically available 2-3 weeks after sample collection, with the sample to be submitted by the 7th of the month.
- Fasting Required
- No
- Method
- LC-MS/MS
Sample Collection
Complete and sign the Test Send Out Consent Form (Form 35) as it is mandatory. Inform your doctor about any medications or supplements you are taking.
Method: Venipuncture
Laboratory Analysis
A healthcare professional will collect a blood sample via venipuncture from your arm. The procedure takes a few minutes and may cause minor discomfort.
Report Delivery
Apply pressure to the puncture site to prevent bleeding. Resume normal activities unless advised otherwise. Store the sample as per instructions for stability.
Timeline: Results are typically available 2-3 weeks after sample collection, with the sample to be submitted by the 7th of the month.
Patient Instructions
About This Test
Who Should Get This Test
The primary purpose of the Carbamazepine Free Test is to confirm or rule out hypersensitivity to carbamazepine in individuals showing adverse symptoms during treatment. By quantifying CBZ-specific IgE antibodies, it aids in diagnosing drug-induced allergic reactions, guiding clinical decisions to discontinue or switch medications, and preventing life-threatening complications such as Stevens-Johnson syndrome or toxic epidermal necrolysis.
How to Prepare
- Use 1 Red Top (No Additive) tube for sample collection
- Collect 4 mL of blood (2 mL minimum)
- Do not use SST gel barrier tubes
- Ship sample refrigerated or frozen
- Ensure the Test Send Out Consent Form (Form 35) is duly filled and submitted
Doctor's Notes
Reviewed by Dr SHAILAJA RAGHUNATH MURDESHWAR — MBBS, MD (General Medicine) · Reg. No. 8052
"Carbamazepine hypersensitivity can be severe and life-threatening. This test helps in early detection by measuring specific IgE antibodies, allowing for timely intervention and medication adjustment."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Sample in incorrect tube type (e.g., SST gel barrier tubes)
- Hemolyzed or lipemic samples
- Insufficient sample volume
- Missing consent form
Understanding Your Results
Negative (<0.35 kU/L)
No detectable IgE antibodies; hypersensitivity unlikely, but clinical correlation is needed.
Positive (≥0.35 kU/L)
Presence of IgE antibodies; indicates possible hypersensitivity to carbamazepine. Consult a doctor for further evaluation.
Equivocal (borderline)
Inconclusive; repeat testing or additional clinical assessment may be recommended.
If you experience symptoms such as severe skin rashes, fever, jaundice, or neurological issues while taking carbamazepine, consult your doctor immediately. After receiving test results, discuss them with your healthcare provider for appropriate management.
Limitations
- ⚠This test detects IgE-mediated hypersensitivity only; it may not identify non-IgE reactions
- ⚠False negatives can occur in early sensitization phases
- ⚠Clinical correlation is essential for diagnosis
Risks & Considerations
- ●Minor bruising or swelling at the puncture site
- ●Rare risk of infection
- ●Slight discomfort during blood draw
Interfering Factors
- ●Recent administration of antihistamines or immunosuppressants may affect IgE levels
- ●Cross-reactivity with other aromatic anticonvulsants like phenytoin
- ●Sample hemolysis or improper storage can alter results
Frequently Asked Questions
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