CASP8 Gene Autoimmune lymphoproliferative syndrome type 2B NGS Genetic Test
Short Name: CASP8 ALPS Type 2B NGS Test
Also known as: ALPS Type 2B Genetic Test, CASP8 Mutation Analysis, Autoimmune Lymphoproliferative Syndrome Type 2B NGS Test
CASP8 Gene Autoimmune lymphoproliferative syndrome type 2B NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 weeks. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
To detect mutations in the CASP8 gene for diagnosis of Autoimmune Lymphoproliferative Syndrome Type 2B (ALPS Type 2B).
- Test Code
- 2373
- Price
- ₹20,000
- Sample Type
- Blood or Extracted DNA or One drop Blood on FTA Card
- Result Time
- 3 to 4 weeks
- Fasting Required
- No
- Method
- Next-Generation Sequencing (NGS)
Sample Collection
No specific preparation required. Genetic counseling recommended.
Method: Venipuncture or Blood Drop on FTA Card
Laboratory Analysis
Sample collected by trained phlebotomist at home or lab.
Report Delivery
Sample sent to laboratory for analysis.
Timeline: 3 to 4 weeks
Patient Instructions
About This Test
Who Should Get This Test
To detect mutations in the CASP8 gene for diagnosis of Autoimmune Lymphoproliferative Syndrome Type 2B (ALPS Type 2B).
How to Prepare
- Fast for not required
- Provide clinical history and family pedigree
- Ensure proper labeling of sample
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"NGS-based testing for CASP8 gene provides precise diagnosis for ALPS Type 2B, enabling targeted management and family counseling."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Insufficient sample volume
- Hemolyzed or clotted sample
- Incorrect patient information
Understanding Your Results
If symptoms suggestive of ALPS Type 2B are present, or for genetic counseling after positive result.
Limitations
- ⚠May not detect all types of mutations
- ⚠Variants of uncertain significance may require further analysis
- ⚠Does not rule out other genetic disorders
Risks & Considerations
- ●Minimal physical risk
- ●Potential psychological impact of diagnosis
- ●Risk of incidental findings
Interfering Factors
- ●Poor sample quality
- ●Contamination during collection
- ●Incorrect sample storage
Compare With Similar Tests
| Test | CASP8 Gene Autoimmune lymphoproliferative syndrome type 2B NGS Genetic Test | FAS Gene Mutation Test for ALPS Type 1 |
|---|---|---|
| Comparison | CASP8 Gene Autoimmune lymphoproliferative syndrome type 2B NGS Genetic Test |
Frequently Asked Questions
What is ALPS Type 2B?
What is the CASP8 gene?
What are the symptoms of ALPS Type 2B?
How is ALPS Type 2B diagnosed?
What is the cost of the CASP8 NGS Genetic Test?
Is fasting required for this test?
How is the sample collected?
How long does it take to get results?
Can this test be done for children?
Is home sample collection available?
What if the test shows a variant of uncertain significance?
Who should undergo this test?
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Your Data Privacy
Your medical data is protected under Indian law.
✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.
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