chr. 15q11 Gene Prader-Willi syndrome NGS Genetic Test
Short Name: Prader-Willi Syndrome NGS Test
Also known as: Prader-Willi Syndrome NGS Panel, 15q11 Gene Sequencing, PWS Genetic Test
chr. 15q11 Gene Prader-Willi syndrome NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in Results are typically delivered in 3 to 4 weeks from sample receipt.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
The purpose of this test is to identify genetic variants in chromosome 15q11 that cause Prader-Willi syndrome using Next Generation Sequencing, enabling accurate diagnosis and appropriate clinical management.
- Test Code
- 4483
- Price
- ₹20,000
- Sample Type
- Blood or Extracted DNA or One drop Blood on FTA Card
- Result Time
- Results are typically delivered in 3 to 4 weeks from sample receipt.
- Fasting Required
- No
- Method
- Next Generation Sequencing (NGS)
Sample Collection
A genetic counselling session is required prior to testing. Clinical history of the patient and a family pedigree chart should be provided.
Method: Peripheral blood draw / FTA card spot
Laboratory Analysis
A small blood sample is collected by a trained phlebotomist. If using an FTA card, a few drops of blood are placed on the card.
Report Delivery
The sample is sent to the laboratory for analysis. Results will be available in 3 to 4 weeks.
Timeline: Results are typically delivered in 3 to 4 weeks from sample receipt.
Patient Instructions
About This Test
Who Should Get This Test
The purpose of this test is to identify genetic variants in chromosome 15q11 that cause Prader-Willi syndrome using Next Generation Sequencing, enabling accurate diagnosis and appropriate clinical management.
How to Prepare
- Fasting is not required
- Inform the laboratory if the patient has received a bone marrow transplant
- A valid doctor's prescription and genetic counseling may be required
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"This genetic test is valuable for families with a history of Prader-Willi syndrome. Genetic counseling provides critical support to address the psychological and medical aspects of the diagnosis."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Improperly labelled sample
- Hemolyzed blood sample
- Inadequate sample volume
Understanding Your Results
Positive for a pathogenic variant in 15q11
Confirms the diagnosis of Prader-Willi syndrome. Genetic counseling is recommended.
Negative for pathogenic variants
No genetic cause identified; other causes should be considered.
Variant of uncertain significance
Additional testing and family studies may be needed.
Consult your doctor if you notice symptoms of Prader-Willi syndrome such as poor feeding in infancy, persistent hypotonia, developmental delay, or excessive hunger with weight gain.
Limitations
- ⚠NGS may not detect large chromosomal deletions or uniparental disomy affecting the entire chromosome; additional testing may be required.
- ⚠Variants of uncertain significance may need further family studies.
- ⚠This test only covers the specified gene region and may not identify all causes of Prader-Willi syndrome.
Risks & Considerations
- ●Minimal risk of bleeding or hematoma at puncture site
- ●Dizziness or fainting during blood draw
- ●No direct medical risks associated with genetic testing
Interfering Factors
- ●Recent bone marrow transplantation
- ●Blood sample contamination or hemolysis
- ●DNA degradation due to improper storage
- ●Previous allogeneic transplantation
Frequently Asked Questions
What is Prader-Willi syndrome?
What does this NGS genetic test detect?
What sample is required for the test?
Is fasting required?
How long will the results take?
What is the cost of the test?
Is home sample collection available?
Why is genetic counseling needed before the test?
How accurate is this NGS test?
Are there any risks associated with the test?
Can this test be done for children?
Will insurance cover this test?
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We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
Your Data Privacy
Your medical data is protected under Indian law.
✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.
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