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DNA Labs India

Chromosome Analysis (Karyotype) Couple Blood Test

DNA Labs India | ISO 9001:2015 Certified

Chromosome Analysis (Karyotype) Couple Blood Test

Short Name: Karyotype Couple Test

Also known as: Karyotyping, Chromosome Analysis, Couple Karyotype Test

Chromosome Analysis (Karyotype) Couple Blood Test test available at DNA Labs India for ₹7,600. Uses Cell Culture, Robotic Microscopy, G-banding Karyotyping on Blood samples. Results in 10–12 working days from sample receipt. Free home collection in 300+ cities across India.

Blood TestAdults🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr SULOCHANA HEMCHANDRA HOLLA

Dr SULOCHANA HEMCHANDRA HOLLA

Consultant Medical Geneticist · Reg: 8532

Last reviewed: September 7, 2026

Overview

This test is prescribed to identify structural or numerical chromosomal abnormalities, such as balanced translocations, in couples. These abnormalities may not affect the parents but can lead to miscarriage, genetic disorders in offspring, or infertility. Early detection aids in informed family planning, including PGD or prenatal testing.

Test Code
311
Price
₹7,600
Sample Type
Blood
Result Time
10–12 working days from sample receipt
Fasting Required
No
Method
Cell Culture, Robotic Microscopy, G-banding Karyotyping
Step 1

Sample Collection

Ensure the Chromosome & FISH Analysis Requisition form (Form 17) is duly filled and signed by the referring physician.

Method: Venipuncture

Step 2

Laboratory Analysis

A phlebotomist will collect a blood sample via venipuncture from a vein in the arm.

Step 3

Report Delivery

Apply pressure to the puncture site to prevent bruising. Resume normal activities.

Timeline: 10–12 working days from sample receipt

Patient Instructions

1
Before the Test:Complete mandatory Form 17. No fasting required.
2
During the Test:Blood sample collection takes about 5-10 minutes.
3
After the Test:Mild soreness at puncture site possible. Results delivered in 10-12 working days.

About This Test

Who Should Get This Test

This test is prescribed to identify structural or numerical chromosomal abnormalities, such as balanced translocations, in couples. These abnormalities may not affect the parents but can lead to miscarriage, genetic disorders in offspring, or infertility. Early detection aids in informed family planning, including PGD or prenatal testing.

How to Prepare

  • Complete Form 17 before sample collection.
  • No fasting required.
  • Avoid strenuous exercise before sample collection.
  • Inform the phlebotomist of any bleeding disorders or medications.

Doctor's Notes

Reviewed by — MBBS, MD (Medical Genetics) · Reg. No. 8532

"This test is crucial for couples with recurrent pregnancy loss or infertility to identify chromosomal causes, enabling informed family planning through options like PGD or prenatal testing."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood
Sample Volume5-10 mL
ContainerSodium Heparin Tube
Collection MethodVenipuncture

Sample Stability

Room temperature: 24-48 hours
Refrigerated: Up to 72 hours
Sample Rejection Criteria:
  • Clotted sample
  • Incorrect container or insufficient volume
  • Missing or incomplete requisition form

Understanding Your Results

Karyotype results are analyzed to identify chromosomal abnormalities. A normal result shows 46 chromosomes with no structural issues. Abnormal results indicate deviations that may require genetic counseling for implications.
Normal Karyotype: 46,XX or 46,XY – No abnormalities detected.
Numerical Abnormality: e.g., Trisomy 21 – Extra chromosome 21.
Structural Abnormality: e.g., Balanced Translocation – Altered chromosome structure without loss.
Mosaicism – Presence of two or more cell lines with different karyotypes.
Sex Chromosome Abnormalities: e.g., Turner Syndrome (45,X) or Klinefelter Syndrome (47,XXY).
⚠️ When to Consult a Doctor:

Consult a doctor or genetic counselor if results show abnormalities, if there are recurrent pregnancy losses, or for guidance on family planning options.

Limitations

  • ⚠May not detect small chromosomal deletions or duplications
  • ⚠Cannot identify single-gene disorders
  • ⚠Results may require confirmation with advanced tests like FISH or microarray

Risks & Considerations

  • ●Minimal risk from blood draw: bruising, dizziness, or infection at puncture site.

Interfering Factors

  • ●Contaminated or poorly preserved sample
  • ●Low cell viability in blood sample
  • ●Technical errors in cell culture or microscopy

Compare With Similar Tests

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ComparisonChromosome Analysis (Karyotype) Couple Blood Test

Frequently Asked Questions

Is fasting required for the Chromosome Analysis (Karyotype) Couple Blood Test in India?
No, fasting from food is not required. However, a duly filled Chromosome & FISH Analysis Requisition form (Form 17) is mandatory.
Do you provide help in understanding my genetic test results?
Yes, we offer free post?test telephonic genetic counseling with certified genetic counselors. Call 09395142800 during working hours for a detailed explanation.
How soon will I receive my ISO?certified digital report?
Reports are typically delivered within 10–12 working days via email and WhatsApp. You can also download from our secure patient portal.
Is there an extra charge for home collection in my city?
No, home sample collection is completely free of charge across all our service locations (300+ cities). The price remains ?7,600 inclusive of all costs.
How can I book the Chromosome Analysis test via WhatsApp or Phone?
Simply call 09395142800 or send a message on WhatsApp with your name, location, and preferred date. Our team will guide you on the mandatory requisition form and confirm the free home collection slot.
What is the purpose of the Chromosome Analysis (Karyotype) Couple Blood Test?
This test identifies chromosomal abnormalities in couples to explain recurrent miscarriages, infertility, or assess risks for genetic disorders in offspring, aiding family planning.
Who should consider taking this test?
Couples with recurrent pregnancy loss, difficulty conceiving, family history of chromosomal disorders, or those planning pregnancy with known genetic risks.
What does a karyotype report show?
It shows the number and structure of chromosomes, detecting abnormalities like extra chromosomes, missing chromosomes, or structural rearrangements.
What are the common chromosomal abnormalities detected?
Common abnormalities include balanced translocations, trisomies (e.g., Down syndrome), monosomies, and sex chromosome anomalies like Turner or Klinefelter syndrome.
Is the test safe and what are the risks?
The test involves a standard blood draw, which is generally safe with minimal risks like bruising or dizziness. No significant health risks are associated with the analysis.
Can the test be done for individuals or only couples?
This specific test is designed for couples. Individual karyotype tests are available separately for diagnostic purposes.
What steps should I take after receiving the test results?
Discuss the results with your referring doctor or genetic counselor to understand implications and options such as PGD, prenatal testing, or other family planning strategies.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

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Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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