Chromosomes 18, X & Y Test
Also known as: FISH for Chromosomes 18, X, Y, Chromosome 18 and Sex Chromosome Analysis
Chromosomes 18, X & Y Test test available at DNA Labs India for ₹6,000. Uses FISH (Fluorescence In Situ Hybridization) on Amniotic fluid / Chorionic villi / Cord blood samples. Results in 3-4 days. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
The purpose of Chromosomes 18, X & Y testing is to detect numerical abnormalities in chromosomes 18, X, and Y, which can cause genetic disorders. This aids in diagnosis, prognosis, and informed decision-making for patients and families.
- Test Code
- 2967
- Price
- ₹6,000
- Sample Type
- Amniotic fluid / Chorionic villi / Cord blood
- Result Time
- 3-4 days
- Fasting Required
- No
- Method
- FISH (Fluorescence In Situ Hybridization)
Sample Collection
A doctor's prescription is required for this test, except in cases of surgery, pregnancy, or travel abroad. No specific preparation is needed, but patients should inform their healthcare provider of any medications or conditions.
Method: As per sample type, typically invasive for prenatal samples
Laboratory Analysis
Sample collection is performed by trained professionals. For amniotic fluid or chorionic villi, it is an invasive procedure done under ultrasound guidance.
Report Delivery
After sample collection, apply pressure to the site if needed. Monitor for any signs of infection or discomfort and follow post-procedure instructions from the healthcare provider.
Timeline: 3-4 days
Patient Instructions
About This Test
Who Should Get This Test
The purpose of Chromosomes 18, X & Y testing is to detect numerical abnormalities in chromosomes 18, X, and Y, which can cause genetic disorders. This aids in diagnosis, prognosis, and informed decision-making for patients and families.
How to Prepare
- Ensure sterile collection conditions
- Use appropriate containers as specified
- Label samples correctly with patient details
- Transport samples at ambient or cool temperature as indicated
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"This test is essential for early detection of chromosomal abnormalities, aiding in timely intervention and management for conditions like Trisomy 18 and sex chromosome disorders."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Contaminated samples
- Insufficient sample volume
- Improper labeling or container
Understanding Your Results
Normal
No abnormalities detected in chromosomes 18, X, and Y. Further testing may not be needed unless symptoms persist.
Abnormal - Trisomy 18
Three copies of chromosome 18 detected, indicating Edwards syndrome. Associated with severe developmental issues and often poor prognosis.
Abnormal - Sex Chromosome Aneuploidy
Variations in X or Y chromosomes, such as XXX, XXY, or XYY, which may lead to conditions like Turner or Klinefelter syndrome with variable symptoms.
Consult a doctor if test results are abnormal, if symptoms like developmental delays or recurrent infections persist, or for genetic counseling and management options.
Limitations
- ⚠FISH may not detect all chromosomal abnormalities, such as subtle structural changes
- ⚠Limited to specific chromosomes (18, X, Y); comprehensive karyotyping may be needed for full analysis
Risks & Considerations
- ●For invasive samples: Risk of infection, miscarriage (for amniocentesis), or discomfort
- ●Minimal risks for non-invasive samples like cord blood
Interfering Factors
- ●Sample contamination
- ●Poor sample quality
- ●Technical errors in FISH procedure
Frequently Asked Questions
What is Chromosomes 18, X & Y testing?
Why is this test recommended?
How is the test performed?
What is the cost of the test?
Is fasting required before the test?
How long does it take to get results?
What do abnormal results mean?
Are there any risks associated with the test?
Can this test be done during pregnancy?
Is home sample collection available?
What should I do if I have symptoms of a chromosomal disorder?
How accurate is the FISH method for this test?
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Reference Laboratory Services
We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
Your Data Privacy
Your medical data is protected under Indian law.
✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.
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