Skip to main content
DNA Labs India

CLN6 Gene Ceroid lipofuscinosis neuronal type 6 NGS Genetic Test

DNA Labs India | ISO 9001:2015 Certified

CLN6 Gene Ceroid lipofuscinosis neuronal type 6 NGS Genetic Test

Short Name: CLN6 NGS Genetic Test

Also known as: CLN6 disease, Neuronal ceroid lipofuscinosis type 6

CLN6 Gene Ceroid lipofuscinosis neuronal type 6 NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 Weeks. Free home collection in 300+ cities across India.

NGS Genetic Test🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr SULOCHANA HEMCHANDRA HOLLA

Dr SULOCHANA HEMCHANDRA HOLLA

Consultant Medical Geneticist · Reg: 8532

Last reviewed: September 7, 2026

Overview

To diagnose Ceroid lipofuscinosis neuronal type 6 by detecting pathogenic mutations in the CLN6 gene using NGS technology, facilitating early intervention and genetic counseling.

Test Code
1910
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
3 to 4 Weeks
Fasting Required
No
Method
Next-Generation Sequencing (NGS)
Step 1

Sample Collection

Provide detailed clinical history of the patient and undergo a genetic counselling session to draw a pedigree chart of family members affected with ceroid lipofuscinosis neuronal type 6.

Method: Venipuncture

Step 2

Laboratory Analysis

Blood sample collected via venipuncture by a trained phlebotomist under sterile conditions.

Step 3

Report Delivery

Apply pressure to the puncture site to prevent bruising; the sample is then sent to the laboratory for analysis.

Timeline: 3 to 4 Weeks

Patient Instructions

1
Before the Test:Complete genetic counselling, provide informed consent, and share clinical and family history.
2
During the Test:Blood sample collection is the only procedure; no active participation required during the test itself.
3
After the Test:Wait for results; schedule genetic counselling to discuss findings and next steps.

About This Test

Who Should Get This Test

To diagnose Ceroid lipofuscinosis neuronal type 6 by detecting pathogenic mutations in the CLN6 gene using NGS technology, facilitating early intervention and genetic counseling.

How to Prepare

  • Complete genetic counselling and pedigree chart
  • No fasting required
  • Collect blood in an EDTA tube
  • Ensure proper labeling and sample integrity

Doctor's Notes

Reviewed by — MBBS, MD (Medical Genetics) · Reg. No. 8532

"Genetic testing for CLN6 is crucial for early diagnosis and family planning, aiding in management and genetic counseling."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card
Sample Volume3-5 ml
ContainerEDTA tube
Collection MethodVenipuncture

Sample Stability

Room temperature48 hours
Refrigerated (2-8°C)7 days
Sample Rejection Criteria:
  • Insufficient sample volume
  • Contaminated or hemolyzed sample
  • Improper labeling or documentation

Understanding Your Results

Results indicate the presence or absence of pathogenic mutations in the CLN6 gene, guiding clinical diagnosis and management.
📊

Pathogenic variant detected

Confirms diagnosis of CLN6 disease

Action: Consult a geneticist for management and family counseling

📊

No pathogenic variant detected

CLN6 disease unlikely based on this gene analysis

Action: Consider other genetic tests if symptoms persist

📊

Variant of uncertain significance (VUS)

Further testing or family studies may be needed for clarification

Action: Genetic counselling recommended for interpretation

⚠️ When to Consult a Doctor:

If you or your child experience symptoms such as progressive vision loss, seizures, intellectual disability, or have a family history of neuronal ceroid lipofuscinosis, consult a healthcare provider for evaluation.

Limitations

  • ⚠May not detect all possible genetic variants
  • ⚠Genetic variants of uncertain significance (VUS) may be reported
  • ⚠Test does not rule out other genetic or metabolic disorders

Risks & Considerations

  • ●Minimal risk of bruising or infection at the blood draw site
  • ●Potential psychological impact from genetic results; genetic counseling provided

Interfering Factors

  • ●Sample contamination
  • ●Degraded DNA
  • ●Incorrect sample handling or storage

Compare With Similar Tests

TestCLN6 Gene Ceroid lipofuscinosis neuronal type 6 NGS Genetic TestCLN3 Gene NGS TestWhole Exome SequencingLysosomal Storage Disorders Panel
ComparisonCLN6 Gene Ceroid lipofuscinosis neuronal type 6 NGS Genetic Test

Frequently Asked Questions

What is CLN6 disease?
CLN6 disease is a rare genetic disorder caused by mutations in the CLN6 gene, leading to neuronal ceroid lipofuscinosis type 6, which affects the nervous system with symptoms like vision loss and seizures.
What are the symptoms of CLN6?
Common symptoms include progressive vision loss, seizures, intellectual disability, loss of motor skills, and speech problems, varying in severity.
How is CLN6 diagnosed?
Diagnosis involves genetic testing, specifically an NGS Genetic Test for the CLN6 gene, to detect mutations confirming the disorder.
What does the NGS Genetic Test involve?
The test uses Next-Generation Sequencing to analyze the CLN6 gene from a blood or DNA sample, identifying pathogenic variants.
What is the cost of the test?
The CLN6 Gene NGS Genetic Test costs INR 20000 at DNA Labs India, including home sample collection.
Is home sample collection available?
Yes, we offer free home sample collection across India for online bookings, ensuring convenience.
How long does it take to get results?
Results are typically available in 3 to 4 weeks after sample collection, delivered via online portal, email, or WhatsApp.
What if a variant of uncertain significance is found?
A variant of uncertain significance may require further testing or family studies; genetic counseling is recommended for interpretation.
Can the test be done on children?
Yes, the test can be performed on individuals of all ages, including children, with parental consent and genetic counseling.
Is genetic counselling included?
Yes, genetic counselling is included to help draw a pedigree chart, discuss results, and provide guidance.
How accurate is the test?
The NGS Genetic Test is highly accurate for detecting mutations in the CLN6 gene, but no test is 100% definitive for all variants.
What are the treatment options for CLN6?
There is no cure for CLN6; management focuses on symptom relief, supportive care, and genetic counseling for families.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

Related Tests

Angelman Syndrome Test

₹10,000

Duchenne / Becker Muscular Dystrophy (DMD / BMD) Gene Mutation Test

₹14,000

Episodic Ataxia Type 1 Hotspot Test

₹11,500

Episodic Ataxia Comprehensive Profile Hotspot Test

₹16,000

Megalencephalic Leukoencephalopathy with Subcortical Cysts Van Der Knaap and Nalband MLC Gene Hotspot Mutation Test

₹7,500

Analyzer 18 SMA 18 Test Panel

₹1,755
For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

Book Your Test

Enter your details and we'll connect you within 15 minutes.

🧬

Quick Connect

Enter your mobile number and we’ll connect you with the team.

+91

✅ Connecting you now...

🔒 Your number is used to respond to this request.