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DNA Labs India

Cortisone (Compound E) 24 Hour Urine Test

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Cortisone (Compound E) 24 Hour Urine Test

Short Name: Cortisone 24-Hour Urine Test

Also known as: Cortisol Urine Test, Compound E Urine Test, 24-Hour Urine Cortisone Test

Cortisone (Compound E) 24 Hour Urine Test test available at DNA Labs India for ₹30,000. Uses LC-MS/MS on 24-hour urine samples. Results in Reports delivered online or via email/WhatsApp within 2-3 weeks after sample receipt.. Free home collection in 300+ cities across India.

Urine TestAll Ages🏠 Home Collection

🩺 Medically Reviewed By

Overview

To quantify urinary cortisol and cortisone for evaluating adrenal function, aiding in the diagnosis of hormonal imbalances and adrenal disorders.

Test Code
354
Price
₹30,000
Sample Type
24-hour urine
Result Time
Reports delivered online or via email/WhatsApp within 2-3 weeks after sample receipt.
Fasting Required
No
Method
LC-MS/MS
Step 1

Sample Collection

Consult healthcare provider about medications. Ensure proper container with boric acid or plan for refrigeration. Record 24-hour urine volume accurately.

Method: 24-hour urine collection

Step 2

Laboratory Analysis

Collect all urine over 24 hours in a clean container. Keep refrigerated or with preservative. Store in a cool, dark place.

Step 3

Report Delivery

Return sample to lab promptly. Complete test request form with volume details. Ensure specimen is labeled correctly.

Timeline: Reports delivered online or via email/WhatsApp within 2-3 weeks after sample receipt.

Patient Instructions

1
Before the Test:No specific fasting, but follow collection instructions. Avoid vigorous exercise or stress during collection period.
2
During the Test:Collect urine as per protocol. Ensure container is sealed and stored correctly.
3
After the Test:Return sample to lab. Await report, typically available in 2-3 weeks.

About This Test

Who Should Get This Test

To quantify urinary cortisol and cortisone for evaluating adrenal function, aiding in the diagnosis of hormonal imbalances and adrenal disorders.

How to Prepare

  • Use a container with 10g boric acid or keep urine refrigerated during collection.
  • Collect all urine for 24 hours, starting after first void.
  • Record total volume on container and test form.
  • Ship refrigerated or frozen to lab.
  • Submit duly filled Test Send Out Consent Form (Form 35).

Doctor's Notes

Reviewed by — MBBS, MD (General Medicine) · Reg. No. 8052

"This test is crucial for evaluating adrenal function, especially when symptoms suggest cortisol excess or deficiency. Accurate 24-hour collection is key for reliable results."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample Type24-hour urine
Sample Volume10 mL aliquot
ContainerScrew capped container with 10g boric acid or refrigerated
Collection Method24-hour urine collection

Sample Stability

Room Temperature: 4 hours
Refrigerator: 72 hours
Frozen: 60 days
Sample Rejection Criteria:
  • Insufficient sample volume
  • Improper preservation or container
  • Missing consent form or incorrect labeling
  • Sample not shipped under required conditions

Understanding Your Results

Results are interpreted based on reference ranges and clinical symptoms. Elevated levels may indicate Cushing's syndrome, while low levels could suggest Addison's disease.
📊

High cortisol and cortisone levels

📊

Low cortisol and cortisone levels

📊

Levels within reference ranges

⚠️ When to Consult a Doctor:

If test results are abnormal, or if symptoms persist despite normal results, consult an endocrinologist for further evaluation and management.

Limitations

  • Results may vary with individual physiology; interpret in clinical context
  • Not suitable for point-of-care testing; requires lab analysis
  • Does not distinguish between free and bound cortisol fractions without additional tests

Risks & Considerations

  • Non-invasive; no significant risks associated with urine collection
  • Potential for skin irritation if boric acid contacts skin, handle with care

Interfering Factors

  • Improper urine collection timing or volume
  • Use of certain medications like steroids or oral contraceptives
  • Physical stress or acute illness during collection
  • Non-compliance with preservative or refrigeration instructions

Compare With Similar Tests

TestCortisone (Compound E) 24 Hour Urine TestSerum Cortisol TestACTH Stimulation Test
ComparisonCortisone (Compound E) 24 Hour Urine Test

Frequently Asked Questions

What is the cost of the Cortisone 24-hour urine test?
The test costs INR 30000, with free home sample collection available in many cities.
How do I collect the urine sample?
Collect all urine over 24 hours in a container with boric acid or keep refrigerated. Record the total volume.
What conditions does this test diagnose?
It helps diagnose adrenal disorders like Cushing's syndrome and Addison's disease, and assess hormonal imbalances.
Is fasting required for this test?
No, fasting is not required, but follow specific collection instructions.
How long does it take to get results?
Reports are typically available within 2-3 weeks after sample receipt.
Can medications affect the test results?
Yes, certain medications like steroids can interfere. Inform your doctor about all medications.
Is home sample collection available?
Yes, DNA Labs India offers free home collection for online bookings in numerous cities.
What should I do if I miss collecting all urine?
Discard the sample and restart the 24-hour collection to ensure accuracy.
How is the sample preserved during collection?
Use 10g boric acid in the container or keep the urine refrigerated throughout collection.
What are normal cortisol levels in urine?
Typically, 20-90 ?g/24h, but ranges may vary by lab. Refer to your report for specifics.
Can this test be done at any age?
Yes, it is suitable for all ages, but collection methods may differ for children; consult a healthcare provider.
Is the test covered by insurance?
Coverage varies; check with your insurance provider for details.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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