CR2 Gene Immunodeficiency, common variable type 7 NGS Genetic Test
Short Name: CR2 Gene CVID7 NGS Test
Also known as: CVID7, Common Variable Immunodeficiency Type 7, CR2 Gene Mutation Test
CR2 Gene Immunodeficiency, common variable type 7 NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 weeks from sample receipt. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
The purpose of the CR2 Gene Immunodeficiency NGS Genetic Test is to identify mutations in the CR2 gene that cause common variable immunodeficiency type 7 (CVID7). This test aids in confirming diagnosis, guiding treatment decisions, assessing family risk, and enabling personalized medical management for individuals with suspected immunodeficiency disorders.
- Test Code
- 2594
- Price
- ₹20,000
- Sample Type
- Blood or Extracted DNA or One drop Blood on FTA Card
- Result Time
- 3 to 4 weeks from sample receipt
- Fasting Required
- No
- Method
- Next-Generation Sequencing (NGS)
Sample Collection
No specific preparation required. Ensure clinical history and family pedigree information are available for genetic counseling.
Method: Venipuncture
Laboratory Analysis
Blood sample collected via venipuncture or one drop on FTA card by a trained phlebotomist.
Report Delivery
Sample labeled correctly and transported to the laboratory under ambient room temperature conditions.
Timeline: 3 to 4 weeks from sample receipt
Patient Instructions
About This Test
Who Should Get This Test
The purpose of the CR2 Gene Immunodeficiency NGS Genetic Test is to identify mutations in the CR2 gene that cause common variable immunodeficiency type 7 (CVID7). This test aids in confirming diagnosis, guiding treatment decisions, assessing family risk, and enabling personalized medical management for individuals with suspected immunodeficiency disorders.
How to Prepare
- Use sterile collection tubes or FTA cards
- Label samples with patient details and test information
- Avoid hemolysis during blood collection
- Store samples at room temperature if not processed immediately
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"Early genetic testing for CR2 mutations is essential for diagnosing CVID7, guiding personalized treatment plans, and managing recurrent infections effectively."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed or clotted blood samples
- Insufficient sample volume
- Incorrectly labeled or unlabeled samples
Understanding Your Results
Positive for pathogenic CR2 mutation
Confirms diagnosis of common variable immunodeficiency type 7 (CVID7). Genetic counseling and immunological management recommended.
Negative for pathogenic CR2 mutation
No detectable mutations in the CR2 gene. Clinical correlation and further testing may be needed if symptoms persist.
Variant of uncertain significance (VUS)
A genetic variant was found but its clinical significance is unknown. Repeat testing or family studies may be advised.
Consult a doctor if you experience recurrent infections, chronic diarrhea, autoimmune symptoms, or have a family history of immunodeficiency. Also, seek genetic counseling after receiving test results for proper interpretation and management.
Limitations
- ⚠May not detect all types of genetic variants, such as large deletions or duplications
- ⚠Requires genetic counseling for proper interpretation of results
- ⚠Results should be correlated with clinical symptoms and family history
Risks & Considerations
- ●Minimal risk from blood draw, such as bruising or infection at the puncture site
- ●Psychological impact of genetic results, requiring counseling support
Interfering Factors
- ●Sample contamination during collection or processing
- ●Degraded DNA due to improper storage or handling
- ●Presence of inhibitors in the sample affecting sequencing
Compare With Similar Tests
| Test | CR2 Gene Immunodeficiency, common variable type 7 NGS Genetic Test | BTK Gene Mutation Test | CD40LG Gene Test | IGHM Gene Test |
|---|---|---|---|---|
| Comparison | CR2 Gene Immunodeficiency, common variable type 7 NGS Genetic Test | Detects mutations for X-linked agammaglobulinemia, a different primary immunodeficiency disorder. | Identifies mutations causing hyper-IgM syndrome, another type of immunodeficiency. | Tests for mutations associated with agammaglobulinemia, focusing on immunoglobulin production. |
Frequently Asked Questions
What is CR2 gene immunodeficiency?
What are the symptoms of CR2 gene immunodeficiency?
How is CR2 gene immunodeficiency diagnosed?
What is the cost of the CR2 Gene Immunodeficiency NGS Genetic Test?
How long does it take to get results?
Is fasting required for this test?
What sample types are accepted?
Can this test be done at home?
What does a positive test result mean?
What if the test result is negative?
Is genetic counseling provided with the test?
Are there any risks associated with this test?
Related Tests
Reference Laboratory Services
We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
Your Data Privacy
Your medical data is protected under Indian law.
✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.
Book Your Test
Enter your details and we'll connect you within 15 minutes.