DCC Gene Mirror movements type 1 NGS Genetic Test
Short Name: DCC Gene Mirror Movements NGS
Also known as: DCC Gene Mirror Movements Type 1 NGS Genetic DNA Test, Mirror Movements Type 1 DCC Gene Test, DCC Gene Mutation Analysis
DCC Gene Mirror movements type 1 NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in Reports are delivered within 3 to 4 weeks from sample receipt.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
The purpose of this test is to detect pathogenic or likely pathogenic variants in the DCC gene using Next-Generation Sequencing technology, helping confirm a diagnosis of Mirror Movements Type 1 and providing information for clinical management and family genetic counseling.
- Test Code
- 4298
- Price
- ₹20,000
- Sample Type
- Blood or Extracted DNA or One drop Blood on FTA Card
- Result Time
- Reports are delivered within 3 to 4 weeks from sample receipt.
- Fasting Required
- No
- Method
- Next-Generation Sequencing (NGS)
Sample Collection
Please share your clinical history and any family pedigree information during the pre-test genetic counseling session. No fasting is required.
Method: Blood draw / FTA card spot
Laboratory Analysis
A trained phlebotomist or home collection technician will collect a blood sample into an EDTA tube; alternatively, one drop of blood may be placed on an FTA card.
Report Delivery
You may resume normal activities immediately after sample collection. The laboratory will process the sample and share the report in 3 to 4 weeks.
Timeline: Reports are delivered within 3 to 4 weeks from sample receipt.
Patient Instructions
About This Test
Who Should Get This Test
The purpose of this test is to detect pathogenic or likely pathogenic variants in the DCC gene using Next-Generation Sequencing technology, helping confirm a diagnosis of Mirror Movements Type 1 and providing information for clinical management and family genetic counseling.
How to Prepare
- No fasting is required
- Patient should carry a valid ID and test requisition form
- Inform the sample collector about any history of organ or stem cell transplant
- Ensure clinical history and pedigree chart are available for genetic counseling
- The sample may be collected at any time of the day
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"Targeted DCC gene analysis by NGS is a robust approach for patients presenting with congenital mirror movements. The test result should be correlated with clinical examination and family pedigree by the treating neurologist and genetic counselor."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Improperly labeled sample
- Highly hemolyzed or clotted blood unsuitable for DNA extraction
- FTA card exposed to contamination or moisture
- Sample received in an unapproved container
Understanding Your Results
Positive
A pathogenic or likely pathogenic variant in the DCC gene was detected. Clinical correlation and genetic counseling are recommended.
Negative
No pathogenic variant was detected in the tested regions of the DCC gene. This reduces but does not exclude the diagnosis.
Variant of Uncertain Significance
A DNA change of unknown clinical significance was found. Additional family studies may be required to clarify its role.
Benign or Likely Benign Variant
A variant unlikely to be associated with disease was detected. No significant clinical impact is expected.
Consult a clinical geneticist, neurologist, or genetic counselor if the test result is positive, if a variant of uncertain significance is reported, or if the family history suggests a hereditary movement disorder.
Limitations
- ⚠NGS may not detect large deletions or duplications, deep intronic variants, or repeat expansions
- ⚠A negative result does not completely rule out DCC-associated Mirror Movements Type 1
- ⚠A variant of uncertain significance may require additional family segregation studies
- ⚠This test is targeted to the DCC gene and does not assess all genetic causes of mirror movements
Risks & Considerations
- ●Physical risks are minimal and limited to slight pain or bruising at the blood collection site
- ●Genetic test results may reveal information with implications for other family members
- ●A variant of uncertain significance may cause anxiety and may require additional family testing
Interfering Factors
- ●Poor DNA quality or degraded extracted DNA
- ●Contamination during sample collection or processing
- ●Sample mix-up or incorrect labeling
- ●Allogeneic bone marrow or stem cell transplant can complicate germline interpretation
- ●Rare intronic or structural variants that are not detected by standard NGS bioinformatics
Compare With Similar Tests
| Test | DCC Gene Mirror movements type 1 NGS Genetic Test | |||
|---|---|---|---|---|
| Comparison | DCC Gene Mirror movements type 1 NGS Genetic Test |
Frequently Asked Questions
What is the DCC Gene Mirror Movements Type 1 NGS Genetic Test?
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What type of sample is required?
Is fasting required before the test?
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How long does it take to receive the report?
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Why is genetic counseling recommended before the test?
Can this NGS test detect all genetic causes of mirror movements?
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