DNASE1 Gene Systemic lupus erythematosus NGS Genetic Test
Short Name: DNASE1 SLE NGS Test
Also known as: Deoxyribonuclease 1 Gene Test, Lupus Genetic Test, SLE NGS Test
DNASE1 Gene Systemic lupus erythematosus NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses NGS Technology on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 Weeks. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
The purpose of the DNASE1 Gene NGS Genetic Test is to identify mutations in the DNASE1 gene that may be associated with Systemic Lupus Erythematosus (SLE). This helps in assessing genetic risk, supporting early diagnosis, and guiding personalized management strategies for autoimmune conditions.
- Test Code
- 5142
- Price
- ₹20,000
- Sample Type
- Blood or Extracted DNA or One drop Blood on FTA Card
- Result Time
- 3 to 4 Weeks
- Fasting Required
- No
- Method
- NGS Technology
Sample Collection
Genetic counselling session and clinical history review are recommended before sample collection.
Method: Venipuncture or FTA Card
Laboratory Analysis
Blood sample is collected via venipuncture or using an FTA card with one drop of blood.
Report Delivery
Sample is processed for NGS analysis; wait for report and consult a healthcare provider for interpretation.
Timeline: 3 to 4 Weeks
Patient Instructions
About This Test
Who Should Get This Test
The purpose of the DNASE1 Gene NGS Genetic Test is to identify mutations in the DNASE1 gene that may be associated with Systemic Lupus Erythematosus (SLE). This helps in assessing genetic risk, supporting early diagnosis, and guiding personalized management strategies for autoimmune conditions.
How to Prepare
- Ensure patient identification and consent
- Use sterile equipment for blood draw
- Label sample correctly with patient details
- Store sample at ambient room temperature if not immediate processing
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"This test is crucial for early detection of genetic predisposition to SLE, especially in patients with family history or symptoms, aiding in personalized management."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed or clotted blood sample
- Insufficient sample volume
- Incorrect labeling or missing information
Understanding Your Results
Pathogenic variant detected
Increased genetic risk for SLE; recommend clinical evaluation and genetic counselling
No pathogenic variant detected
No increased risk from DNASE1 gene; other factors may contribute to SLE
Variant of uncertain significance
Further research needed; monitor symptoms and consult specialist
If symptoms of SLE are present, such as joint pain, rash, fatigue, or if there is a family history of autoimmune diseases, consult a doctor for evaluation and test recommendation.
Limitations
- ⚠Test only analyzes the DNASE1 gene; other SLE-related genes are not covered
- ⚠Results do not alone diagnose SLE; clinical correlation is required
- ⚠Genetic counselling is recommended for interpretation
- ⚠May not detect all genetic variations due to technical limitations
Risks & Considerations
- ●Minimal risk from blood draw, such as bruising or infection
- ●Genetic privacy concerns; ensure data protection
- ●Emotional impact of genetic risk information
Interfering Factors
- ●Sample contamination
- ●Degraded DNA quality
- ●Improper sample storage
Compare With Similar Tests
| Test | DNASE1 Gene Systemic lupus erythematosus NGS Genetic Test | ANA Test | Anti-dsDNA Test | Complement C3/C4 Test | HLA Typing |
|---|---|---|---|---|---|
| Comparison | DNASE1 Gene Systemic lupus erythematosus NGS Genetic Test |
Frequently Asked Questions
What is the DNASE1 Gene NGS Genetic Test?
Why is this test important for SLE?
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Is fasting required before the test?
How long does it take to get results?
What do the results indicate?
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Who should consider this test?
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Reference Laboratory Services
We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
Your Data Privacy
Your medical data is protected under Indian law.
✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.
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