DNASE1L3 Gene Systemic lupus erythematosus type 16 NGS Genetic Test
Short Name: DNASE1L3 SLE NGS Test
Also known as: SLE Type 16, DNASE1L3-related SLE
DNASE1L3 Gene Systemic lupus erythematosus type 16 NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses NGS Technology on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 weeks. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
To identify mutations in the DNASE1L3 gene and other genetic variants associated with systemic lupus erythematosus type 16, aiding in diagnosis, risk assessment, and personalized treatment planning.
- Test Code
- 5143
- Price
- ₹20,000
- Sample Type
- Blood or Extracted DNA or One drop Blood on FTA Card
- Result Time
- 3 to 4 weeks
- Fasting Required
- No
- Method
- NGS Technology
Sample Collection
No special preparation required. Provide clinical history and undergo genetic counseling.
Method: Blood Draw
Laboratory Analysis
A blood sample will be drawn by a trained phlebotomist using sterile equipment.
Report Delivery
Apply pressure to the puncture site to stop bleeding. Keep the area clean.
Timeline: 3 to 4 weeks
Patient Instructions
About This Test
Who Should Get This Test
To identify mutations in the DNASE1L3 gene and other genetic variants associated with systemic lupus erythematosus type 16, aiding in diagnosis, risk assessment, and personalized treatment planning.
How to Prepare
- Ensure proper patient identification
- Use sterile collection tubes
- Label samples with patient details
- Transport samples at ambient temperature
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"This genetic test is crucial for identifying hereditary risk factors for SLE, enabling early intervention and family planning."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed samples
- Insufficient volume
- Improper labeling
Understanding Your Results
Positive for DNASE1L3 mutation
Increased genetic risk for systemic lupus erythematosus; clinical correlation and further evaluation recommended.
Negative for DNASE1L3 mutation
No pathogenic variants detected, but clinical symptoms may require additional testing.
If symptoms of SLE are present, such as fatigue, joint pain, or rash, or if there is a family history of autoimmune diseases, consult a rheumatologist or geneticist.
Limitations
- ⚠May not detect all genetic variants
- ⚠Results require clinical correlation
Risks & Considerations
- ●Bruising at puncture site
- ●Minor infection risk
- ●Fainting during blood draw
Interfering Factors
- ●Contaminated sample
- ●Degraded DNA
Compare With Similar Tests
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| Comparison | DNASE1L3 Gene Systemic lupus erythematosus type 16 NGS Genetic Test |
Frequently Asked Questions
What is the DNASE1L3 gene?
How is DNASE1L3 related to SLE?
What does the NGS Genetic Test involve?
What are the symptoms of SLE?
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Is home sample collection available?
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Is genetic counseling required?
Can this test be used for other autoimmune diseases?
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Reference Laboratory Services
We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
Your Data Privacy
Your medical data is protected under Indian law.
✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.
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