Estrogen Total Serum Test
Short Name: Estrogen Total Serum
Also known as: Total Estrogen Test, Serum Total Estrogen, Total Serum Estrogens Test, Estrogen Panel Serum
Estrogen Total Serum Test test available at DNA Labs India for ₹16,000. Uses Extraction, Radioimmunoassay (RIA) on Serum samples. Results in Results are typically available after 2–3 weeks from the date the sample reaches the reference laboratory. The sample must be submitted by the 7th of the month for batch processing.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Ramarao Paidisetty
Consultant Biochemist · Reg: 21504
Last reviewed: September 7, 2026
Overview
The purpose of the Estrogen Total Serum Test is to measure the total concentration of all estrogen hormones in the blood to help diagnose hormonal imbalances, evaluate reproductive health, assess menopausal status, investigate infertility, and monitor hormone therapy or conditions affecting the endocrine system.
- Test Code
- 542
- ICD Code
- E28.9
- Price
- ₹16,000
- Sample Type
- Serum
- Result Time
- Results are typically available after 2–3 weeks from the date the sample reaches the reference laboratory. The sample must be submitted by the 7th of the month for batch processing.
- Fasting Required
- No
- Method
- Extraction, Radioimmunoassay (RIA)
Sample Collection
No specific fasting is required for this test. A duly filled Test Send Out Consent Form (Form 35) is mandatory. Inform your doctor about any medications, supplements, or hormone therapies you are currently taking. Your doctor may advise testing on a specific day of your menstrual cycle for optimal interpretation.
Method: Venipuncture
Laboratory Analysis
A blood sample of 3 mL (minimum 1.5 mL) will be drawn from a vein in your arm using standard venipuncture technique into an SST (Serum Separator Tube). The procedure takes only a few minutes.
Report Delivery
After sample collection, slight bruising or soreness at the puncture site may occur and typically resolves within a few hours. The sample will be shipped refrigerated or frozen to the reference laboratory for analysis.
Timeline: Results are typically available after 2–3 weeks from the date the sample reaches the reference laboratory. The sample must be submitted by the 7th of the month for batch processing.
Patient Instructions
About This Test
Who Should Get This Test
The purpose of the Estrogen Total Serum Test is to measure the total concentration of all estrogen hormones in the blood to help diagnose hormonal imbalances, evaluate reproductive health, assess menopausal status, investigate infertility, and monitor hormone therapy or conditions affecting the endocrine system.
How to Prepare
- Duly filled Test Send Out Consent Form (Form 35) is mandatory at the time of sample collection
- Inform your doctor about any current medications, HRT, or hormone supplements
- Sample must be collected in an SST (Serum Separator Tube)
- Ship refrigerated or frozen to the reference laboratory
- Sample should reach the reference laboratory by the 7th of the month for batch processing
Doctor's Notes
Reviewed by Dr Ramarao Paidisetty — MBBS, MD (Biochemistry) · Reg. No. 21504
"The Estrogen Total Serum Test provides a comprehensive assessment of all circulating estrogen hormones in the blood. It is particularly valuable when evaluating unexplained symptoms of hormonal imbalance such as irregular menstrual periods, infertility, hot flashes, or fatigue. I recommend this test when a broad evaluation of estrogen status is needed rather than measuring individual estrogen fractions, especially in cases where clinical presentation does not clearly point to a single hormonal cause."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Insufficient sample volume (less than 1.5 mL)
- Hemolyzed or lipemic samples
- Samples not shipped or stored at the required temperature
- Missing or incomplete Test Send Out Consent Form (Form 35)
- Unlabelled or improperly labelled samples
Understanding Your Results
Elevated Total Estrogen
High estrogen levels can cause symptoms including weight gain, bloating, mood changes, irregular menstrual periods, breast tenderness, and may increase the risk of blood clots and certain hormone-sensitive conditions.
Low Total Estrogen
Low estrogen levels can cause symptoms such as hot flashes, vaginal dryness, decreased bone density, mood disturbances, fatigue, and infertility.
Normal Total Estrogen
Normal results suggest that the endocrine system is producing appropriate levels of estrogen. If symptoms persist despite normal results, further evaluation with additional hormonal tests may be warranted.
Consult your endocrinologist or healthcare provider if your Estrogen Total Serum Test results are outside the normal reference range, or if you continue to experience symptoms such as irregular periods, infertility, hot flashes, severe mood swings, unexplained weight gain, or persistent fatigue. Early evaluation and management can help prevent complications related to hormonal imbalances.
Limitations
- ⚠This test measures total estrogen and does not provide separate quantification of E1, E2, and E3 unless individual tests are ordered
- ⚠Results must be interpreted in the context of clinical symptoms, menstrual cycle phase, and other hormonal tests
- ⚠Reference ranges vary based on age, sex, menstrual cycle phase, and the performing laboratory
- ⚠This is a send-out test to a reference laboratory; turnaround time is longer than routine in-house hormone tests
- ⚠Sample must reach the laboratory by the 7th of the month for batch processing
Risks & Considerations
- ●Minor bruising or soreness at the puncture site
- ●Slight risk of infection at the blood draw site
- ●Rarely, lightheadedness or fainting during blood draw
Interfering Factors
- ●Hormone replacement therapy (HRT) or oral contraceptive use may alter estrogen levels
- ●Recent consumption of estrogen-containing supplements or herbal products
- ●Certain medications including corticosteroids, antibiotics, and anti-epileptic drugs
- ●Liver disease may affect estrogen metabolism and circulating levels
- ●Pregnancy significantly elevates estrogen levels and must be considered in interpretation
- ●Obesity can increase peripheral conversion of androgens to estrogens
Compare With Similar Tests
| Test | Estrogen Total Serum Test | Estradiol (E2) Serum Test | Estrone (E1) Serum Test | FSH and LH Test | Progesterone Serum Test |
|---|---|---|---|---|---|
| Comparison | Estrogen Total Serum Test |
Frequently Asked Questions
What is the Estrogen Total Serum Test?
Why is the Estrogen Total Serum Test recommended?
What is the cost of the Estrogen Total Serum Test in India?
How is the Estrogen Total Serum Test performed?
Do I need to fast before the Estrogen Total Serum Test?
What sample is required for the Estrogen Total Serum Test?
How long does it take to get the results of the Estrogen Total Serum Test?
What are normal total estrogen levels?
What does a high total estrogen level indicate?
What does a low total estrogen level indicate?
Is the Estrogen Total Serum Test safe?
Is a consent form required for the Estrogen Total Serum Test?
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