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DNA Labs India

F11 Gene Factor XI deficiency NGS Genetic Test

DNA Labs India | ISO 9001:2015 Certified

F11 Gene Factor XI deficiency NGS Genetic Test

Short Name: Factor XI Deficiency NGS Test

Also known as: Hemophilia C, Rosenthal syndrome, Plasma thromboplastin antecedent deficiency

F11 Gene Factor XI deficiency NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 weeks. Free home collection in 300+ cities across India.

NGS Genetic Test🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr SULOCHANA HEMCHANDRA HOLLA

Dr SULOCHANA HEMCHANDRA HOLLA

Consultant Medical Geneticist · Reg: 8532

Last reviewed: September 7, 2026

Overview

To identify pathogenic mutations in the F11 gene that cause Factor XI deficiency, enabling accurate diagnosis, carrier testing, and informed clinical management.

Test Code
2583
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
3 to 4 weeks
Fasting Required
No
Method
Next-Generation Sequencing (NGS)
Step 1

Sample Collection

No specific preparation required. Provide clinical history and family pedigree during genetic counseling.

Method: Venipuncture or finger-prick

Step 2

Laboratory Analysis

Blood sample collected via venipuncture or finger-prick. For FTA card, a single drop of blood is applied.

Step 3

Report Delivery

Apply pressure to the puncture site to prevent bruising. Store sample as per instructions.

Timeline: 3 to 4 weeks

Patient Instructions

1
Before the Test:Genetic counseling session to discuss test implications and draw a family pedigree.
2
During the Test:Sample collection procedure as per standard protocols.
3
After the Test:Report delivery and follow-up counseling to discuss results and next steps.

About This Test

Who Should Get This Test

To identify pathogenic mutations in the F11 gene that cause Factor XI deficiency, enabling accurate diagnosis, carrier testing, and informed clinical management.

How to Prepare

  • Ensure proper labeling of sample
  • Use sterile collection equipment
  • Transport sample at ambient temperature

Doctor's Notes

Reviewed by — MBBS, MD (Medical Genetics) · Reg. No. 8532

"This genetic test is crucial for diagnosing Factor XI deficiency, especially in patients with unexplained bleeding or family history. Early detection guides management and genetic counseling."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card
Sample Volume3-5 mL
ContainerEDTA tube or FTA card
Collection MethodVenipuncture or finger-prick

Sample Stability

Blood sample stable for 48 hours at room temperature
Extracted DNA stable for longer periods if stored properly
Sample Rejection Criteria:
  • Hemolyzed or clotted sample
  • Insufficient sample volume
  • Incorrect sample type or container

Understanding Your Results

Results indicate the presence or absence of mutations in the F11 gene. A positive result confirms Factor XI deficiency, while a negative result may require further testing if symptoms persist.
📊

Pathogenic variant detected

Confirms Factor XI deficiency; refer to hematologist for management.

📊

No pathogenic variant detected

Factor XI deficiency unlikely; consider other causes of bleeding.

📊

Variant of uncertain significance

Further testing or family studies recommended.

⚠️ When to Consult a Doctor:

Consult a hematologist or genetic counselor if results are positive, or if bleeding symptoms persist despite negative results.

Limitations

  • ⚠May not detect all types of mutations (e.g., large deletions)
  • ⚠Requires genetic counseling for interpretation
  • ⚠Not a substitute for functional clotting assays

Risks & Considerations

  • ●Minor bruising at puncture site
  • ●Rare risk of infection
  • ●Psychological impact of genetic results

Interfering Factors

  • ●Recent blood transfusion
  • ●Contaminated sample
  • ●Degraded DNA

Frequently Asked Questions

What is Factor XI deficiency?
Factor XI deficiency is a rare bleeding disorder caused by mutations in the F11 gene, leading to impaired blood clotting and excessive bleeding.
How is the F11 Gene Factor XI Deficiency NGS Genetic Test performed?
The test uses next-generation sequencing (NGS) to analyze the F11 gene from a blood or DNA sample, identifying mutations that cause Factor XI deficiency.
Who should consider this test?
Individuals with symptoms like easy bruising, heavy menstrual periods, or a family history of bleeding disorders should consider this test.
What is the cost of the test?
The test costs INR 20000, including home sample collection across India.
How long does it take to get results?
Results are typically available within 3 to 4 weeks after sample collection.
Is fasting required for this test?
No, fasting is not required for the F11 Gene Factor XI Deficiency NGS Genetic Test.
What sample types are accepted?
Blood, extracted DNA, or one drop of blood on an FTA card are accepted.
Can this test detect carriers of Factor XI deficiency?
Yes, the test can identify carriers who have one mutated copy of the F11 gene.
What are the limitations of the test?
The test may not detect all mutation types, and genetic counseling is recommended for result interpretation.
Is the test available in my city?
Yes, home sample collection is available in numerous cities across India, including Mumbai, Delhi, Bangalore, and more.
What should I do if my test results are positive?
Consult a hematologist or genetic counselor for management options, which may include avoiding certain medications or treatments.
Is genetic counseling included with the test?
Yes, a genetic counseling session is included to draw a family pedigree and discuss test implications.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

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Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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