Factor V Leiden Detection (RNA Detection) Qualitative Test
Short Name: Factor V Leiden RNA Test
Also known as: Factor V Leiden Mutation Test, F5 Gene Mutation Test, Thrombophilia Genetic Test
Factor V Leiden Detection (RNA Detection) Qualitative Test test available at DNA Labs India for ₹6,800. Uses Real-Time PCR on Whole Blood samples. Results in 3 working days for report generation; online access within 36 hours via email.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
The purpose of the Factor V Leiden Detection (RNA Detection) Qualitative Test is to diagnose the presence of the Factor V Leiden mutation, which is a genetic risk factor for abnormal blood clotting. This test helps in identifying individuals at increased risk for thrombotic events such as DVT and PE, enabling timely medical intervention, lifestyle modifications, and prophylactic treatments to prevent complications.
- Test Code
- 3308
- Price
- ₹6,800
- Sample Type
- Whole Blood
- Result Time
- 3 working days for report generation; online access within 36 hours via email.
- Fasting Required
- No
- Method
- Real-Time PCR
Sample Collection
No specific preparation is required. Patients should sign a consent document and bring any relevant clinical history.
Method: Venipuncture
Laboratory Analysis
A blood sample will be drawn from a vein in the arm using standard venipuncture techniques.
Report Delivery
Apply pressure to the puncture site to prevent bleeding. Resume normal activities unless advised otherwise.
Timeline: 3 working days for report generation; online access within 36 hours via email.
Patient Instructions
About This Test
Who Should Get This Test
The purpose of the Factor V Leiden Detection (RNA Detection) Qualitative Test is to diagnose the presence of the Factor V Leiden mutation, which is a genetic risk factor for abnormal blood clotting. This test helps in identifying individuals at increased risk for thrombotic events such as DVT and PE, enabling timely medical intervention, lifestyle modifications, and prophylactic treatments to prevent complications.
How to Prepare
- Sign the consent form before sample collection
- Bring any previous medical reports or clinical history
- Inform the phlebotomist about any medications or supplements being taken
- Stay hydrated and avoid strenuous exercise before the test if possible
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"This test is crucial for patients with a family history of thrombosis or recurrent blood clots, as it helps in early diagnosis and management of thrombophilic disorders."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Incorrectly labeled or unlabeled samples
- Samples collected in wrong container type
- Hemolyzed, clotted, or insufficient sample volume
Understanding Your Results
Mutation Detected
Positive for Factor V Leiden mutation. Indicates increased risk of thrombosis. Consult a hematologist for further evaluation and management.
Action: Consider anticoagulant therapy, lifestyle changes, and regular monitoring.
Mutation Not Detected
Negative for Factor V Leiden mutation. No increased genetic risk from this mutation, but other clotting factors may still be present.
Action: Discuss with physician if symptoms persist; consider other thrombophilia tests.
Consult a doctor immediately if you experience symptoms of DVT (e.g., leg pain, swelling) or PE (e.g., sudden shortness of breath, chest pain), or if you have a family history of clotting disorders.
Limitations
- ⚠This test detects only the Factor V Leiden mutation and not other thrombophilic disorders
- ⚠It is a qualitative test and does not quantify the mutation load
- ⚠Results should be interpreted in conjunction with clinical history and other diagnostic tests
Risks & Considerations
- ●Minor bruising or discomfort at the blood draw site
- ●Rare risk of infection or excessive bleeding
- ●No significant risks associated with the test itself
Interfering Factors
- ●Hemolyzed or lipemic blood samples may affect test accuracy
- ●Recent blood transfusions could interfere with results
- ●Improper sample storage or handling may lead to false negatives
Compare With Similar Tests
| Test | Factor V Leiden Detection (RNA Detection) Qualitative Test | Activated Protein C Resistance Test | Genetic Testing for Other Mutations | Complete Blood Count (CBC) | Prothrombin Time (PT) and aPTT Tests |
|---|---|---|---|---|---|
| Comparison | Factor V Leiden Detection (RNA Detection) Qualitative Test |
Frequently Asked Questions
What is the Factor V Leiden Detection (RNA Detection) Qualitative Test?
Why is this test recommended?
How is the test performed?
What is the cost of the test in India?
Is fasting required before the test?
How long does it take to get results?
What does a positive result mean?
What does a negative result mean?
Is the test covered by insurance?
Are there any risks associated with the test?
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₹4,500Reference Laboratory Services
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