FASLG Gene Autoimmune lymphoproliferative syndrome type 1B NGS Genetic Test
Short Name: FASLG Gene ALPS Type 1B NGS Test
Also known as: ALPS Type 1B Genetic Test, FASLG Mutation Analysis, Autoimmune Lymphoproliferative Syndrome Type 1B Test
FASLG Gene Autoimmune lymphoproliferative syndrome type 1B NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 Weeks. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Pasupathy Arumugam
Consultant Pathologist · Reg: 21521
Last reviewed: September 7, 2026
Overview
The purpose of this test is to detect mutations in the FASLG gene that cause Autoimmune Lymphoproliferative Syndrome Type 1B. It aids in confirming diagnosis, understanding disease prognosis, and guiding therapeutic interventions such as immunosuppressive therapy and monitoring for autoimmune complications or lymphoma.
- Test Code
- 2370
- Price
- ₹20,000
- Sample Type
- Blood or Extracted DNA or One drop Blood on FTA Card
- Result Time
- 3 to 4 Weeks
- Fasting Required
- No
- Method
- Next-Generation Sequencing (NGS)
Sample Collection
No specific preparation required. Provide clinical history and family pedigree as per pre-test information.
Method: Venipuncture or FTA Card
Laboratory Analysis
A blood sample is drawn from a vein or a saliva sample is collected using standard protocols.
Report Delivery
Apply pressure to the puncture site if blood is drawn. No special aftercare is typically needed.
Timeline: 3 to 4 Weeks
Patient Instructions
About This Test
Who Should Get This Test
The purpose of this test is to detect mutations in the FASLG gene that cause Autoimmune Lymphoproliferative Syndrome Type 1B. It aids in confirming diagnosis, understanding disease prognosis, and guiding therapeutic interventions such as immunosuppressive therapy and monitoring for autoimmune complications or lymphoma.
How to Prepare
- Bring identification and doctor's referral
- Avoid certain medications if advised by the physician
- Ensure proper labeling of samples
Doctor's Notes
Reviewed by Dr Pasupathy Arumugam — MBBS, MD (Pathology) · Reg. No. 21521
"This genetic test is essential for confirming ALPS Type 1B diagnosis, guiding immunosuppressive therapy, and monitoring for complications like lymphoma. Early detection can improve patient outcomes."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed sample
- Insufficient sample volume
- Incorrect sample container or labeling
Understanding Your Results
Pathogenic variant detected
Confirms diagnosis of ALPS Type 1B. Guide treatment with immunosuppressive therapy and recommend family screening.
No pathogenic variant detected
ALPS Type 1B is unlikely. Consider other genetic or clinical causes for symptoms.
Variant of uncertain significance
Further testing, family studies, or clinical correlation may be needed for clarification.
If symptoms of ALPS such as enlarged lymph nodes, recurrent infections, or autoimmune disorders persist, or if there is a family history of ALPS, consult a geneticist or immunologist promptly.
Limitations
- ⚠May not detect all genetic variants
- ⚠Requires genetic counseling for interpretation
- ⚠Does not cover other ALPS-related genes
Risks & Considerations
- ●Minimal physical risk from blood draw, such as bruising or infection
- ●Potential psychological impact of genetic results, including anxiety
- ●Risk of incidental findings unrelated to ALPS
Interfering Factors
- ●Sample contamination
- ●Insufficient DNA quality
- ●Technical errors during sequencing
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Frequently Asked Questions
What is ALPS Type 1B?
How is ALPS Type 1B diagnosed?
What does the FASLG gene test involve?
What is the cost of the FASLG Gene ALPS Type 1B NGS Test in India?
Is home sample collection available for this test?
How long does it take to get results?
What if the test is positive for a mutation?
Can this test be done for children?
Is the test covered by insurance?
What are the symptoms of ALPS Type 1B?
How accurate is NGS testing for ALPS Type 1B?
What is the next step after diagnosis?
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