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FGF14 Gene Spinocerebellar ataxia type 27, autosomal dominant NGS Genetic Test

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FGF14 Gene Spinocerebellar ataxia type 27, autosomal dominant NGS Genetic Test

Short Name: SCA27 NGS Test

Also known as: SCA27 Genetic Test, FGF14-related Ataxia Test, Spinocerebellar Ataxia Type 27 Gene Test

FGF14 Gene Spinocerebellar ataxia type 27, autosomal dominant NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses NGS Technology on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 weeks. Free home collection in 300+ cities across India.

NGS Genetic TestAdults🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr SULOCHANA HEMCHANDRA HOLLA

Dr SULOCHANA HEMCHANDRA HOLLA

Consultant Medical Geneticist · Reg: 8532

Last reviewed: September 7, 2026

Overview

The purpose of the FGF14 Gene NGS Genetic Test is to diagnose Spinocerebellar ataxia type 27 by identifying mutations in the FGF14 gene, enabling accurate clinical management and genetic counseling.

Test Code
1835
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
3 to 4 weeks
Fasting Required
No
Method
NGS Technology
Step 1

Sample Collection

No specific preparation required. Ensure patient has provided informed consent and clinical history.

Method: Venipuncture for blood

Step 2

Laboratory Analysis

Blood sample collected via venipuncture using standard aseptic techniques. For FTA card, a drop of blood is applied.

Step 3

Report Delivery

Sample labeled correctly and transported to the laboratory at ambient temperature.

Timeline: 3 to 4 weeks

Patient Instructions

1
Before the Test:Genetic counseling session to discuss implications, family history, and consent.
2
During the Test:Blood sample collection; NGS analysis in laboratory.
3
After the Test:Results reviewed by geneticist; counseling provided for interpretation and next steps.

About This Test

Who Should Get This Test

The purpose of the FGF14 Gene NGS Genetic Test is to diagnose Spinocerebellar ataxia type 27 by identifying mutations in the FGF14 gene, enabling accurate clinical management and genetic counseling.

How to Prepare

  • Use EDTA tube for blood samples
  • Store samples at room temperature
  • Avoid hemolysis during collection
  • For FTA card, allow blood to dry completely before packaging

Doctor's Notes

Reviewed by — MBBS, MD (Medical Genetics) · Reg. No. 8532

"Early genetic testing for spinocerebellar ataxia type 27 can facilitate timely diagnosis, management, and genetic counseling for affected families."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card
Sample Volume3-5 mL
ContainerEDTA tube or FTA card
Collection MethodVenipuncture for blood

Sample Stability

Blood samples stable for 48 hours at room temperature
Extracted DNA stable for longer periods if stored properly
Sample Rejection Criteria:
  • Hemolyzed or clotted samples
  • Insufficient sample volume
  • Improperly labeled samples
  • Contaminated samples

Understanding Your Results

Results indicate the presence or absence of pathogenic mutations in the FGF14 gene associated with Spinocerebellar ataxia type 27.
📊

Pathogenic variant detected

Confirms diagnosis of SCA27; genetic counseling recommended

📊

No pathogenic variant detected

SCA27 unlikely; consider other etiologies

📊

Variant of uncertain significance

Further testing and clinical correlation needed

📊

Heterozygous mutation

Autosomal dominant inheritance confirmed

⚠️ When to Consult a Doctor:

Consult a neurologist or geneticist if symptoms of ataxia appear, family history of SCA27, or for genetic counseling regarding test results.

Limitations

  • ⚠May not detect all possible mutations in the FGF14 gene
  • ⚠Results require interpretation by a geneticist or neurologist
  • ⚠Does not exclude other causes of ataxia
  • ⚠Genetic counseling is recommended before and after testing

Risks & Considerations

  • ●Minor bruising or discomfort at blood draw site
  • ●Rare risk of infection
  • ●Psychological impact of genetic results

Interfering Factors

  • ●Sample contamination
  • ●DNA degradation due to improper storage
  • ●Hemolyzed or lipemic blood samples
  • ●Insufficient sample volume

Compare With Similar Tests

TestFGF14 Gene Spinocerebellar ataxia type 27, autosomal dominant NGS Genetic TestSCA1 Genetic TestSCA2 Genetic TestComprehensive Ataxia PanelFGF14 Sequencing Test
ComparisonFGF14 Gene Spinocerebellar ataxia type 27, autosomal dominant NGS Genetic Test

Frequently Asked Questions

What is Spinocerebellar ataxia type 27?
SCA27 is a rare genetic disorder causing progressive cerebellar ataxia, inherited in an autosomal dominant pattern due to FGF14 gene mutations.
How is SCA27 inherited?
SCA27 follows autosomal dominant inheritance; a single mutated gene copy from either parent can cause the disorder.
What are the common symptoms of SCA27?
Symptoms include uncoordinated movements, balance issues, tremors, slurred speech, difficulty swallowing, vision problems, and cognitive decline.
How is SCA27 diagnosed?
Diagnosis involves clinical evaluation, family history, and genetic testing, specifically NGS for FGF14 gene mutations.
What is NGS genetic testing?
Next-Generation Sequencing is a high-throughput method to analyze multiple DNA regions rapidly, detecting mutations accurately.
How accurate is the FGF14 gene test?
The NGS test has high accuracy for detecting known mutations, but genetic counseling is essential for result interpretation.
What is the cost of the FGF14 Gene NGS Test in India?
The test costs INR 20,000 with free home sample collection available across India.
Is home sample collection available for this test?
Yes, DNA Labs India offers free home sample collection for online bookings in many cities across India.
How long does it take to get results?
Results are typically available within 3 to 4 weeks after sample collection.
Can children undergo this genetic test?
While symptoms typically appear in adulthood, testing can be done at any age if clinically indicated, with genetic counseling.
What should I do if the test is positive for SCA27?
A positive result confirms SCA27; consult a neurologist for management and a geneticist for family counseling.
Is genetic counseling recommended before testing?
Yes, genetic counseling is strongly recommended to discuss implications, family history, and psychological support.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

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Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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