Fibroblast Growth Factor (FGF2) Test
Short Name: FGF2 Test
Also known as: Basic Fibroblast Growth Factor Test, bFGF Test, FGF-2 Blood Test, Fibroblast Growth Factor 2 Quantitative Test
Fibroblast Growth Factor (FGF2) Test test available at DNA Labs India for ₹25,000. Uses Immunoassay on Plasma (EDTA) samples. Results in Sample must be submitted by the 7th of the month. Reports are typically available 2–3 weeks after sample acceptance and will be shared via online portal, email, or WhatsApp.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Pasupathy Arumugam
Consultant Pathologist · Reg: 21521
Last reviewed: September 7, 2026
Overview
The primary purpose of the Fibroblast Growth Factor (FGF2) Test is to quantitatively measure the level of FGF2 protein in blood plasma. This measurement aids clinicians, particularly oncologists, in evaluating angiogenic activity associated with certain malignancies. The test serves as a supplementary biomarker that may assist in disease assessment, treatment monitoring, and clinical decision-making when interpreted alongside other diagnostic findings such as imaging, biopsy, and standard tumour markers.
- Test Code
- 557
- CPT Code
- 83520
- ICD Code
- R89.4
- Price
- ₹25,000
- Sample Type
- Plasma (EDTA)
- Result Time
- Sample must be submitted by the 7th of the month. Reports are typically available 2–3 weeks after sample acceptance and will be shared via online portal, email, or WhatsApp.
- Fasting Required
- No
- Method
- Immunoassay
Sample Collection
Ensure the mandatory Test Send Out Consent Form (Form 35) is duly filled and signed prior to sample collection. Inform your healthcare provider about any medications, supplements, or ongoing treatments, particularly anti-angiogenic therapies. No specific fasting is required unless advised by your physician.
Method: Venipuncture
Laboratory Analysis
A trained phlebotomist will collect approximately 2 mL of blood from a vein in your arm into a Lavender Top (EDTA) tube. The procedure typically takes a few minutes and is similar to a routine blood draw.
Report Delivery
The plasma will be separated from the blood within 6 hours of collection using a cold centrifuge and then frozen immediately. The sample must not be thawed at any point during storage or transport. Mild bruising at the puncture site may occur and typically resolves within a few days.
Timeline: Sample must be submitted by the 7th of the month. Reports are typically available 2–3 weeks after sample acceptance and will be shared via online portal, email, or WhatsApp.
Patient Instructions
About This Test
Who Should Get This Test
The primary purpose of the Fibroblast Growth Factor (FGF2) Test is to quantitatively measure the level of FGF2 protein in blood plasma. This measurement aids clinicians, particularly oncologists, in evaluating angiogenic activity associated with certain malignancies. The test serves as a supplementary biomarker that may assist in disease assessment, treatment monitoring, and clinical decision-making when interpreted alongside other diagnostic findings such as imaging, biopsy, and standard tumour markers.
How to Prepare
- Fill and sign the Test Send Out Consent Form (Form 35) before sample collection — this is mandatory
- Blood is collected in a Lavender Top (EDTA) tube (minimum 1 mL plasma required)
- Plasma must be separated within 6 hours of collection using a cold centrifuge
- Freeze the separated plasma immediately after centrifugation
- DO NOT THAW the sample once frozen — ship frozen to the laboratory
- Sample must be submitted by the 7th of the month for processing
Doctor's Notes
Reviewed by Dr Pasupathy Arumugam — MBBS, MD (Pathology) · Reg. No. 21521
"FGF2 is a key mediator of angiogenesis and tumour growth. Elevated circulating FGF2 levels may indicate active disease in certain malignancies and can serve as a supplementary biomarker alongside standard tumour markers. This test is most valuable when interpreted within the full clinical context, including imaging and histopathology. Patients should discuss results with their treating oncologist to determine appropriate next steps."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed samples
- Thawed samples (once frozen, samples must not be thawed)
- Missing or incomplete Test Send Out Consent Form (Form 35)
- Insufficient sample volume (below 1 mL plasma)
- Plasma not separated within 6 hours of collection
- Samples not shipped in frozen condition
Understanding Your Results
FGF2 levels within the laboratory reference range suggest that circulating FGF2 is within expected physiological limits. This does not rule out all disease and should be interpreted with other clinical findings.
Higher-than-reference FGF2 levels may indicate increased angiogenic activity. This has been observed in certain malignancies, cardiovascular conditions, and metabolic disorders such as diabetes. Elevated levels warrant further clinical evaluation by the treating physician or oncologist.
Values near the upper limit of the reference range should be interpreted cautiously and may warrant repeat testing or correlation with additional biomarkers and clinical findings.
Consult your oncologist or treating physician if your FGF2 levels are elevated, if results are inconsistent with your clinical picture, or if you have new or worsening symptoms. Elevated FGF2 may require further investigation with imaging, biopsy, or additional laboratory tests as directed by your healthcare provider.
Limitations
- ⚠This is a send-out test; samples are batched and processed on a specific schedule (by the 7th of each month)
- ⚠Results are available 2–3 weeks after sample acceptance, which may not be suitable for urgent clinical decisions
- ⚠FGF2 levels should not be used as a standalone diagnostic marker for any malignancy
- ⚠Reference ranges may vary between laboratories and should be interpreted in clinical context
- ⚠The test does not provide information about the specific source or type of tumour
Risks & Considerations
- ●Minor bruising or discomfort at the blood draw site
- ●Rarely, slight swelling or infection at the puncture site
- ●Fainting or dizziness during blood collection (uncommon)
Interfering Factors
- ●Hemolyzed blood samples may interfere with accurate FGF2 measurement
- ●Recent surgical procedures, trauma, or acute injury may transiently elevate FGF2 levels
- ●Concurrent use of anti-angiogenic therapies may alter circulating FGF2 concentrations
- ●Improper sample handling, including thawing after freezing, can compromise test accuracy
- ●Delayed separation of plasma beyond the recommended 6-hour window may affect results
- ●Lipemic or severely icteric samples may cause analytical interference
Compare With Similar Tests
| Test | Fibroblast Growth Factor (FGF2) Test | VEGF Test | AFP (Alpha-Fetoprotein) | CEA (Carcinoembryonic Antigen) |
|---|---|---|---|---|
| Comparison | Fibroblast Growth Factor (FGF2) Test |
Frequently Asked Questions
What is the Fibroblast Growth Factor (FGF2) Test?
What is the cost of the FGF2 Test at DNA Labs India?
What sample is required for the FGF2 Test?
Is fasting required before the FGF2 Test?
How long does it take to get FGF2 Test results?
What conditions are associated with elevated FGF2 levels?
Is home sample collection available for the FGF2 Test?
What is the methodology used for the FGF2 Test?
Is the Test Send Out Consent Form (Form 35) mandatory?
Can the FGF2 Test diagnose cancer on its own?
What does a normal FGF2 level mean?
Are there any risks associated with the FGF2 Test?
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