FISH - 11q23 or LSI MLL Gene Breakapart Test
Also known as: MLL Gene FISH Test, 11q23 FISH Test, MLL Breakapart FISH
FISH - 11q23 or LSI MLL Gene Breakapart Test test available at DNA Labs India for ₹6,000. Uses Fluorescence In Situ Hybridization (FISH) on Whole blood or Bone Marrow samples. Results in Report available in 4 working days from sample receipt.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
To detect MLL gene rearrangements for diagnosing and prognosing leukemia and lymphoma, guiding treatment decisions and improving patient care.
- Test Code
- 563
- Price
- ₹6,000
- Sample Type
- Whole blood or Bone Marrow
- Result Time
- Report available in 4 working days from sample receipt.
- Fasting Required
- No
- Method
- Fluorescence In Situ Hybridization (FISH)
Sample Collection
Duly filled Chromosome & FISH analysis Requisition Form (Form 17) is mandatory.
Method: Blood draw or bone marrow aspiration by healthcare professional
Laboratory Analysis
Sample collected by a healthcare professional via blood draw or bone marrow aspiration.
Report Delivery
Ship sample at 18-22°C. DO NOT FREEZE.
Timeline: Report available in 4 working days from sample receipt.
Patient Instructions
About This Test
Who Should Get This Test
To detect MLL gene rearrangements for diagnosing and prognosing leukemia and lymphoma, guiding treatment decisions and improving patient care.
How to Prepare
- Use 2 Green Top (Sodium Heparin) tubes for sample collection
- Maintain sample temperature at 18-22°C during transport
- Complete and attach requisition form (Form 17) to the sample
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"This test is vital for identifying MLL gene rearrangements in leukemia, aiding in precise diagnosis and targeted therapy selection for improved patient outcomes."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Improperly labeled or incomplete requisition form
- Insufficient sample volume
- Sample stored frozen or at incorrect temperature
- Contaminated or hemolyzed sample
Understanding Your Results
Positive
MLL gene rearrangement detected – associated with higher-risk leukemia, may require targeted therapy.
Negative
No MLL gene rearrangement detected – normal MLL gene, but clinical correlation needed for diagnosis.
Consult a doctor if symptoms persist, worsen, or for follow-up after a positive test result to discuss treatment options.
Limitations
- ⚠May not detect all variants of MLL gene rearrangements
- ⚠False negatives possible in rare cases
- ⚠Requires specialized laboratory equipment and expertise
Risks & Considerations
- ●Minor pain or bruising at the blood draw site
- ●Rare risk of infection at bone marrow aspiration site
- ●No significant long-term risks associated with the test
Interfering Factors
- ●Inadequate sample volume
- ●Improper sample storage or transportation
- ●Contamination or degraded sample quality
Compare With Similar Tests
| Test | FISH - 11q23 or LSI MLL Gene Breakapart Test | FISH - BCR-ABL1 Test | Flow Cytometry |
|---|---|---|---|
| Comparison | FISH - 11q23 or LSI MLL Gene Breakapart Test |
Frequently Asked Questions
What is the FISH - 11q23 or LSI MLL Gene Breakapart Test?
Why is this test important for leukemia diagnosis?
What sample is required for this test?
How is the test performed?
What does a positive result mean?
What is the cost of the test?
Is home collection available?
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What should I do to prepare for the test?
Can this test detect all types of leukemia?
What if my result is negative?
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