ZBTB16 Gene Leukemia, acute promyelocytic, PL2F/RARA type NGS Genetic Test
Short Name: ZBTB16 Gene APL NGS Test
Also known as: PL2F/RARA Fusion Test, ZBTB16 Mutation Analysis
ZBTB16 Gene Leukemia, acute promyelocytic, PL2F/RARA type NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 weeks. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
To detect mutations in the ZBTB16 gene and identify the PL2F/RARA fusion protein for the diagnosis and treatment of Acute Promyelocytic Leukemia (APL).
- Test Code
- 2886
- Price
- ₹20,000
- Sample Type
- Blood or Extracted DNA or One drop Blood on FTA Card
- Result Time
- 3 to 4 weeks
- Fasting Required
- No
- Method
- Next-Generation Sequencing (NGS)
Sample Collection
Clinical history review and genetic counseling session to draw a pedigree chart of family members affected with APL.
Method: Blood Draw
Laboratory Analysis
Blood sample collection via venipuncture or using FTA card.
Report Delivery
Sample is sent to the laboratory for NGS analysis.
Timeline: 3 to 4 weeks
Patient Instructions
About This Test
Who Should Get This Test
To detect mutations in the ZBTB16 gene and identify the PL2F/RARA fusion protein for the diagnosis and treatment of Acute Promyelocytic Leukemia (APL).
How to Prepare
- Bring valid ID and doctor's prescription
- Ensure sample is properly labeled
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"This test is crucial for diagnosing APL and guiding targeted therapy to improve patient outcomes."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed sample
- Insufficient sample volume
- Improperly labeled sample
Understanding Your Results
Positive
Mutation detected in ZBTB16 gene or PL2F/RARA fusion present, indicative of APL. Consult oncologist for treatment.
Negative
No mutation detected in ZBTB16 gene or PL2F/RARA fusion absent. Clinical correlation recommended.
If symptoms of APL are present, such as unexplained bleeding or fatigue, or if test results are positive.
Limitations
- ⚠May not detect all genetic variants
- ⚠Requires confirmation with additional tests
Risks & Considerations
- ●Minimal risk from blood draw, such as bruising or infection
- ●No significant risks associated with NGS testing
Interfering Factors
- ●Sample contamination
- ●Degraded DNA
Compare With Similar Tests
| Test | ZBTB16 Gene Leukemia, acute promyelocytic, PL2F/RARA type NGS Genetic Test | PML-RARA FISH Test | Bone Marrow Biopsy | Complete Blood Count (CBC) | Coagulation Profile |
|---|---|---|---|---|---|
| Comparison | ZBTB16 Gene Leukemia, acute promyelocytic, PL2F/RARA type NGS Genetic Test |
Frequently Asked Questions
What is the ZBTB16 Gene NGS Test?
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